Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ralf Bohnensack"'
Publikováno v:
Biochemical and Biophysical Research Communications. 379:909-913
The endocytic protein Numb3 was found to bind to the cytosolic tail of the leukocyte adhesion receptor P-selectin. The N-terminal phosphotyrosine-binding (PTB) domain of Numb3 is responsible for this activity. An alanine scan revealed the FTNAAFD seq
Autor:
Thomas Schlüter, Ralf Bohnensack, Martin Czubayko, Heidi Hahn, Volker Florian, Susan Schreckenberger, Cornelia Kirsch, Peter Knauth
Publikováno v:
Journal of Molecular Biology. 347:813-825
SNX17 is a member of the sorting nexin family (SNX), a group of hydrophilic proteins whose common characteristic property is a phox homology (PX) domain. The PX domain directs SNXs to phosphatidylinositides containing membranes of the endosomal compa
Autor:
Ross Williams, Thomas Schlüter, Peter Knauth, Marnie S. Roberts, Daniel F. Cutler, Ralf Bohnensack
Publikováno v:
Molecular Biology of the Cell. 15:3095-3105
The transient appearance of P-selectin on the surface of endothelial cells helps recruit leukocytes into sites of inflammation. The tight control of cell surface P-selectin on these cells depends on regulated exocytosis of Weibel-Palade bodies where
Publikováno v:
Journal of Bioenergetics and Biomembranes. 36:241-248
The inner membrane of freshly isolated mammalian mitochondria is poorly permeable to Cl(-). Low, nonlytic concentrations (or =30 microM) of long-chain fatty acids or their branched-chain derivatives increase permeation of Cl(-) as indicated from rapi
Publikováno v:
Biochemical and Biophysical Research Communications. 281:1045-1050
P-selectin is a cell adhesion molecule found in platelets and endothelial cells mediating binding of leukocytes. It is stored in secretory granules and expressed at the plasma membrane after cell activation. After rapid internalisation P-selectin rec
Autor:
Thomas Schlüter, Ralf Bohnensack
Publikováno v:
Biochemical Pharmacology. 57:1191-1197
Endothelial cells are able to synthesize von Willebrand factor (vWf) protein, which is then either secreted in a constitutive way or stored within specific cellular secretory granules, the Weibel-Palade bodies. Stimulated secretion of vWf from these
Autor:
Heinz C. Schröder, Werner Geurtsen, Hua Zhu, Werner E.G. Müller, Bernd Lorenz, Ralf Bohnensack, Gabriele Leyhausen
Publikováno v:
Journal of Bone and Mineral Research. 13:803-812
Significant amounts of inorganic polyphosphates and of polyphosphate-degrading exopolyphosphatase activity were detected in human mandibular-derived osteoblast-like cells. The amount of both soluble and insoluble long-chain polyphosphate in unstimula
Autor:
Siegfried Ansorge, Thomas Schlüter, Simone Fritz, Peter Schönfeld, Dirk Reinhold, Ralf Bohnensack, Frank Striggow
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1312(3):255-261
The effect of phorbol 12-myristate 13-acetate (PMA) on the expression and shedding of intercellular adhesion molecule-1 (ICAM-1) was investigated on the hematopoietic cell lines K 562 and U 937 using flow cytometry, fluorescence microscopy and ELISA
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1273(3):223-230
A one-step perifusion technique is described for studying the regulation of energy metabolism in intact hepatocytes and in mitochondria of the same cells after their permeabilization by digitonin. Cell count and activities of glutamate dehydrogenase,
Autor:
Peter Schönfeld, Ralf Bohnensack
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1232(1-2):75-80
The perinatal development of the adenine nucleotide translocation in isolated rat brain mitochondria was studied. For that purpose the content of the adenine nucleotide translocase (ANT), the activity of adenine nucleotide translocation and the contr