Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ralf Bogumil"'
Autor:
Souhaila Bouatra, Farid Aziat, Rupasri Mandal, An Chi Guo, Michael R Wilson, Craig Knox, Trent C Bjorndahl, Ramanarayan Krishnamurthy, Fozia Saleem, Philip Liu, Zerihun T Dame, Jenna Poelzer, Jessica Huynh, Faizath S Yallou, Nick Psychogios, Edison Dong, Ralf Bogumil, Cornelia Roehring, David S Wishart
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73076 (2013)
Urine has long been a "favored" biofluid among metabolomics researchers. It is sterile, easy-to-obtain in large volumes, largely free from interfering proteins or lipids and chemically complex. However, this chemical complexity has also made urine a
Externí odkaz:
https://doaj.org/article/7c98e2038b39406aab29f536252abb90
Autor:
Karsten Suhre, Ralf Bogumil, Cornelia Röhring, Cornelia Prehn, Werner Römisch-Margl, Jerzy Adamski
Publikováno v:
Metabolomics. 8:133-142
Reproducible quantification of metabolites in tissue samples is of high importance for characterization of animal models and identification of metabolic changes that occur in different tissue types in specific diseases. However, the extraction of met
Autor:
Arno Buckendahl, Herbert Tomaso, Ralf Bogumil, Sascha Al Dahouk, Wolf D. Splettstoesser, Sonja Vorderwülbecke, Eric Seibold
Publikováno v:
FEMS Immunology & Medical Microbiology. 49:364-373
Francisella tularensis, the causative agent of tularaemia, is a potential agent of bioterrorism. The phenotypic discrimination of the closely related F. tularensis subspecies and individual strains with traditional methods is difficult and time consu
Publikováno v:
Biotechnology and Bioengineering. 98:440-450
A feasibility study to couple high throughput screening of packed bed chromatography with mass spectrometric detection by SELDI-TOF MS is presented. As model system monoclonal antibodies (mAb) versus host cell protein (HCP) from an industrial cultiva
Autor:
Noelle Potier, Laurent Miguet, Laurent Mauvieux, Raoul Herbrecht, Ralf Bogumil, Alain Van Dorsselaer, Philippe Decloquement
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2006, 5 (9), pp.2258-2269. ⟨10.1021/pr060058y⟩
Journal of Proteome Research, American Chemical Society, 2006, 5 (9), pp.2258-2269. ⟨10.1021/pr060058y⟩
The accurate diagnosis of the different forms of chronic mature B-cell lymphocytic malignancies is of primary importance to determine an appropriate and efficient treatment. Usually, the diagnosis is achieved by morphology and immunophenotyping. Neve
Autor:
Günther Ernst, Annett Bleul, Ferdinand von Eggeling, Christian Melle, Bettina Schimmel, Ralf Bogumil
Publikováno v:
PROTEOMICS. 6:2600-2608
Although colorectal cancer is one of the best-characterized tumors with regard to the multistep progression, it remains one of the most frequent and deadly neoplasms. For a better understanding of the molecular mechanisms behind the process of tumori
Autor:
Claudia A. Mueller, Ralf Bogumil, Gerhard A. Mueller, Cornelia Thedieck, Thomas Flad, Ludmila Mueller, Alexander Beck, Veneta Grigorova, Hubert Kalbacher, Hassan Dihazi
Publikováno v:
PROTEOMICS. 6:364-374
In this study, we describe a differential mass spectrometric technique for the immuno-proteomic analysis of the major histocompatibility complex (MHC) peptides of a renal cell carcinoma (RCC) biopsy compared with the healthy kidney tissue of the same
Autor:
Syrus Karsai, Martina Schnölzer, Matthias Nees, Ralf Bogumil, Franz X. Bosch, Andreas Dietz, Ira Mägele, Mariana Roesch Ely, A. Ruess, Sonja Vorderwülbecke
Publikováno v:
European Journal of Cell Biology. 84:431-444
The calcium-binding proteins of the S100 and the annexin protein families have been implicated in a variety of important physiological functions including membrane remodeling, calcium-related intracellular signaling, cytoskeleton dynamics, tissue hom
Autor:
Gerhard A. Mueller, Markus Kuczyk, Hartmut Kratzin, Hermann Beck, Elke Brunst, Martin Deeg, Ralf Bogumil, Jonathan Tolson, Thomas Flad, Raimund Elsner, Claudia A. Mueller, Andreas Humeny
Publikováno v:
Laboratory Investigation. 84:845-856
The molecular analysis of serum is an important field for the definition of potential diagnostic markers or disease-related protein alterations. Novel proteomic technologies such as the mass spectrometric-based surface-enhanced laser desorption/ioniz
Autor:
Andreas Wiesner, Ferdinand von Eggeling, Sven Koscielny, Christian Melle, Ursula Möller, Günther Ernst, Dirk Osterloh, Bettina Schimmel, Annett Bleul, Ralf Bogumil, Karl-Jürgen Halbhuber
Publikováno v:
Cancer Research. 64:4099-4104
Biomarkers are needed to elucidate the biological background and to improve the detection of cancer. Therefore, we have analyzed laser-microdissected cryostat sections from head and neck tumors and adjacent mucosa on ProteinChip arrays. Two different