Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Ralf Janknecht"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
How the function of the JMJD2D epigenetic regulator is regulated or whether it plays a role in prostate cancer has remained elusive. We found that JMJD2D was overexpressed in prostate tumors, stimulated prostate cancer cell growth and became methylat
Externí odkaz:
https://doaj.org/article/98703971f8d74952b58ab49316928a02
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
The histone demethylase JMJD2A/KDM4A facilitates prostate cancer development, yet how JMJD2A function is regulated has remained elusive. Here, we demonstrate that SET7/9-mediated methylation on 6 lysine residues modulated JMJD2A. Joint mutation of th
Externí odkaz:
https://doaj.org/article/1ea3cc7f1fc84d68b67000cd14f5e2f5
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BHLHE40 is a transcription factor, whose role in colorectal cancer has remained elusive. We demonstrate that the BHLHE40 gene is upregulated in colorectal tumors. Transcription of BHLHE40 was jointly stimulated by the DNA-binding ETV1 protein and two
Externí odkaz:
https://doaj.org/article/913b3fdb76b44d3bb5c53d942bd2482e
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000454 (2019)
[This corrects the article DOI: 10.1371/journal.pbio.2006145.].
Externí odkaz:
https://doaj.org/article/19a2f5a4c9594f1b9a0416a316c4369f
Autor:
Tomomi Matsukura, Chisako Inaba, Esther A. Weygant, Daiki Kitamura, Ralf Janknecht, Hiroyuki Matsumoto, Deborah P. Hyink, Shosaku Kashiwada, Tomoko Obara
Publikováno v:
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Abstract Treatment modalities for kidney disease caused by long‐term exposure to heavy metals, such as cadmium (Cd), are limited. Often, chronic, long‐term environmental exposure to heavy metal is not recognized in the early stages; therefore, ch
Externí odkaz:
https://doaj.org/article/2d64f640c9824dffb9452fafebd66176
Autor:
Sabira Mohammed, Nidheesh Thadathil, Phoebe Ohene-Marfo, Albert L. Tran, Michael Van Der Veldt, Constantin Georgescu, Sangphil Oh, Evan H. Nicklas, Dawei Wang, Nair Hariprasad Haritha, Wenyi Luo, Ralf Janknecht, Benjamin F. Miller, Jonathan D. Wren, Willard M. Freeman, Sathyaseelan S. Deepa
Publikováno v:
Molecular Cancer Research.
Nonalcoholic fatty liver disease (NAFLD) is one of the etiologies that contribute to hepatocellular carcinoma (HCC), and chronic inflammation is one of the proposed mediators of HCC. Since necroptosis is a cell death pathway that induces inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb369dfd6959633eac83e70b2262a747
https://doi.org/10.1158/1541-7786.mcr-22-0820
https://doi.org/10.1158/1541-7786.mcr-22-0820
Correlation between JMJD1 mRNA levels in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e0ce9b1b7940165d6b7f52955805ce
https://doi.org/10.1158/1541-7786.22526895.v1
https://doi.org/10.1158/1541-7786.22526895.v1
Autor:
Sukyung Woo, Kai Ding, Sanam Husain, Resham Bhattacharya, Shailendra Kumar Dhar Dwivedi, Ralf Janknecht, Marie Claire Mukashyaka, Pharavee Jaiprasart, Bharat Devapatla, Samrita Dogra, Deepika Neelakantan
Antibody dilutions used for Western blot and Immunohistochemical analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fa8c0e9a40e3a5fe9531f6a9284ec4
https://doi.org/10.1158/1541-7786.22512820
https://doi.org/10.1158/1541-7786.22512820
Autor:
Sukyung Woo, Kai Ding, Sanam Husain, Resham Bhattacharya, Shailendra Kumar Dhar Dwivedi, Ralf Janknecht, Marie Claire Mukashyaka, Pharavee Jaiprasart, Bharat Devapatla, Samrita Dogra, Deepika Neelakantan
High mortality rates in ovarian cancer are due to late-stage diagnosis when extensive metastases are present, coupled with the eventual development of resistance to standard chemotherapy. There is, thus, an urgent need to identify targetable pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5b9aecfcd6dd53a4c6ff3220347ca3
https://doi.org/10.1158/1541-7786.c.6540346.v1
https://doi.org/10.1158/1541-7786.c.6540346.v1
Autor:
Sukyung Woo, Kai Ding, Sanam Husain, Resham Bhattacharya, Shailendra Kumar Dhar Dwivedi, Ralf Janknecht, Marie Claire Mukashyaka, Pharavee Jaiprasart, Bharat Devapatla, Samrita Dogra, Deepika Neelakantan
ML221 dose-response curves in OvCa cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036cc9e326f52bae8127914a6cfbb7a3
https://doi.org/10.1158/1541-7786.22512835.v1
https://doi.org/10.1158/1541-7786.22512835.v1