Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Ralf, Takors"'
Autor:
Carlos Castillo‐Saldarriaga, Christine N. S. Santos, Stephen Sarria, Parayil K. Ajikumar, Ralf Takors
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Yeast extract (YE) is a complex nutritional source associated with high performance on microbial production processes. However, its inherent compositional variability challenges its scalability. While prior efforts have focused on growth‐a
Externí odkaz:
https://doaj.org/article/388e1bbcf1754c809bb68f94e409f427
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 11, Pp n/a-n/a (2024)
Abstract Microorganisms in large‐scale bioreactors are exposed to heterogeneous environmental conditions due to physical mixing constraints. Nutritional gradients can lead to transient expression of energetically wasteful stress responses and as a
Externí odkaz:
https://doaj.org/article/e533765a5fcb4a8eb15efc97cbf7e125
Publikováno v:
Engineering in Life Sciences, Vol 24, Iss 10, Pp n/a-n/a (2024)
ABSTRACT The L‐tryptophan–derived purple pigment violacein (VIO) is produced in recombinant bacteria and studied for its versatile applications. Microbial synthetic co‐cultures are gaining more importance as efficient factories for synthesizing
Externí odkaz:
https://doaj.org/article/72d9cc89b98f4b42abb85335a15c542a
Publikováno v:
Bioengineering, Vol 11, Iss 9, p 892 (2024)
In recent years, the design–build–test–learn (DBTL) cycle has become a key concept in strain engineering. Modern biofoundries enable automated DBTL cycling using robotic devices. However, both highly automated facilities and semi-automated faci
Externí odkaz:
https://doaj.org/article/780a77adf7f84ce9bd4d210c0f1a87e6
Autor:
Susana Matamouros, Thomas Gensch, Martin Cerff, Christian C. Sachs, Iman Abdollahzadeh, Johnny Hendriks, Lucas Horst, Niklas Tenhaef, Julia Tenhaef, Stephan Noack, Michaela Graf, Ralf Takors, Katharina Nöh, Michael Bott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Bacterial growth rate (µ) depends on the protein synthesis capacity of the cell and thus on the number of active ribosomes and their translation elongation rate. The relationship between these fundamental growth parameters have only been de
Externí odkaz:
https://doaj.org/article/d800cd80ff224159a7ef89ec11071962
Autor:
Felix Werner, Lynn S. Schwardmann, Daniel Siebert, Christian Rückert-Reed, Jörn Kalinowski, Marie-Theres Wirth, Katharina Hofer, Ralf Takors, Volker F. Wendisch, Bastian Blombach
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Background Fatty acid-derived products such as fatty alcohols (FAL) find growing application in cosmetic products, lubricants, or biofuels. So far, FAL are primarily produced petrochemically or through chemical conversion of bio-based feedst
Externí odkaz:
https://doaj.org/article/ac35811c877845a69566f0fec14b7f96
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract l‐Methionine (l‐Met) has gained remarkable interest due to its multifaceted and versatile applications in the fields of nutrition, pharmaceuticals and clinical practice. In this study, the fluxes of the challenging l‐Met biosynthesis i
Externí odkaz:
https://doaj.org/article/553988aca0404f729118f466003165e7
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 1, Pp 148-168 (2023)
Abstract In fed‐batch operated industrial bioreactors, glucose‐limited feeding is commonly applied for optimal control of cell growth and product formation. Still, microbial cells such as yeasts and bacteria are frequently exposed to glucose star
Externí odkaz:
https://doaj.org/article/c7e010e723c340e0a14dcc83603e09a1
Publikováno v:
Engineering in Life Sciences, Vol 22, Iss 2, Pp 70-84 (2022)
Abstract CRISPR interference (CRISPRi) was applied to enable the aerobic production of pyruvate in Escherichia coli MG1655 under glucose excess conditions by targeting the promoter regions of aceE or pdhR. Knockdown strains were cultivated in aerobic
Externí odkaz:
https://doaj.org/article/584e977260dd4e57a07a82ab771d8fc9
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 1, Pp n/a-n/a (2023)
Abstract In nature, microorganisms often reside in symbiotic co‐existence providing nutrition, stability, and protection for each partner by applying “division of labor.” This principle may also be used for the overproduction of targeted compou
Externí odkaz:
https://doaj.org/article/556ace944693474193aae60df30690fd