Zobrazeno 1 - 10
of 1 452
pro vyhledávání: '"Ralf, Paus"'
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Abstract is missing (Short communication)
Externí odkaz:
https://doaj.org/article/2172a3dbe58249598dd45e6d8b0d9978
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Abstract is missing (Short communication)
Externí odkaz:
https://doaj.org/article/b972c799d63e4c4fa28c3c24c7645281
Publikováno v:
Skin Health and Disease, Vol 3, Iss 5, Pp n/a-n/a (2023)
Abstract Background Vascular Endothelial Growth Factor (VEGF)‐A‐mediated angiogenesis participates in the pathogenesis of psoriasis, thus inviting the hypothesis that anti‐VEGF‐A therapy could be beneficial in psoriasis. While anti‐angiogen
Externí odkaz:
https://doaj.org/article/8da86720ec2f4bd2bdef4620da79002d
Publikováno v:
eLife, Vol 12 (2023)
Here, we have explored the involvement of innate lymphoid cells-type 1 (ILC1) in the pathogenesis of alopecia areata (AA), because we found them to be significantly increased around lesional and non-lesional HFs of AA patients. To further explore the
Externí odkaz:
https://doaj.org/article/887e81b5b7b24413a71eab069a83f27b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Hair follicles (HFs) are unique, multi-compartment, mini-organs that cycle through phases of active hair growth and pigmentation (anagen), apoptosis-driven regression (catagen) and relative quiescence (telogen). Anagen HFs have high demands
Externí odkaz:
https://doaj.org/article/e1e71ba6201c426fad695017a9e3361c
Autor:
Kinga Linowiecka, Andrzej T. Slominski, Russel J. Reiter, Markus Böhm, Kerstin Steinbrink, Ralf Paus, Konrad Kleszczyński
Publikováno v:
Antioxidants, Vol 12, Iss 6, p 1155 (2023)
The pineal gland-derived indoleamine hormone, melatonin, regulates multiple cellular processes, ranging from chronobiology, proliferation, apoptosis, and oxidative damage to pigmentation, immune regulation, and mitochondrial metabolism. While melaton
Externí odkaz:
https://doaj.org/article/4b82846600af4b0998b6ccf6964ab092
Publikováno v:
JID Innovations, Vol 2, Iss 3, Pp 100113- (2022)
Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are primary, lymphocytic cicatricial hair loss disorders. These model epithelial stem cell (SC) diseases are thought to result from a CD8+ T-cell‒dominated immune attack on the hair fol
Externí odkaz:
https://doaj.org/article/b6ab5c0f331944b09254f7065f2db80f
Autor:
Ayelet M Rosenberg, Shannon Rausser, Junting Ren, Eugene V Mosharov, Gabriel Sturm, R Todd Ogden, Purvi Patel, Rajesh Kumar Soni, Clay Lacefield, Desmond J Tobin, Ralf Paus, Martin Picard
Publikováno v:
eLife, Vol 10 (2021)
Background: Hair greying is a hallmark of aging generally believed to be irreversible and linked to psychological stress. Methods: Here, we develop an approach to profile hair pigmentation patterns (HPPs) along individual human hair shafts, producing
Externí odkaz:
https://doaj.org/article/35d0dd96c5ff465ebd75a8acc8547e1f
Autor:
Talveen S Purba, Kayumba Ng'andu, Lars Brunken, Eleanor Smart, Ellen Mitchell, Nashat Hassan, Aaron O'Brien, Charlotte Mellor, Jennifer Jackson, Asim Shahmalak, Ralf Paus
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 10, Pp 1-16 (2019)
Abstract Taxanes are a leading cause of severe and often permanent chemotherapy‐induced alopecia. As the underlying pathobiology of taxane chemotherapy‐induced alopecia remains poorly understood, we investigated how paclitaxel and docetaxel damag
Externí odkaz:
https://doaj.org/article/90d9a44b6fc04a7aba33604064c0b735
Publikováno v:
Experimental Dermatology. 32:684-693
It remains unclear how the multifunctional indoleamine neurohormone, melatonin, alters melanin production and melanocytes within intact human epidermis under physiologically relevant conditions. In the current pilot study, we aimed to clarify this in