Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ralf, Kriehuber"'
Autor:
Sherry Freiesleben, Marcus Unverricht-Yeboah, Lea Gütebier, Dagmar Waltemath, Ralf Kriehuber, Olaf Wolkenhauer
Publikováno v:
Frontiers in Systems Biology, Vol 2 (2022)
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are involved in the modulation of the DNA-damage response (DDR) and upon exposure to ionizing radiation (IR), their expression fluctuates. In this study, we propose a workflow that enables the cre
Externí odkaz:
https://doaj.org/article/30a2b70de52447eba1e731dc71d2354d
Autor:
Monika Rabenstein, Marcus Unverricht-Yeboah, Meike Hedwig Keuters, Anton Pikhovych, Joerg Hucklenbroich, Sabine Ulrike Vay, Stefan Blaschke, Anne Ladwig, Helene Luise Walter, Magdalena Beiderbeck, Gereon Rudolf Fink, Michael Schroeter, Ralf Kriehuber, Maria Adele Rueger
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Despite its extensive use in clinical studies, the molecular mechanisms underlying the effects of transcranial direct current stimulation (tDCS) remain to be elucidated. We previously described subacute effects of tDCS on immune- and stem cells in th
Externí odkaz:
https://doaj.org/article/9be52276a1c549fca88fa92fbf69d7f1
Publikováno v:
International Journal of Radiation Biology. 99:64-69
Ionizing radiation causes various types of DNA damage e.g. single strand breaks (SSB) and double strand breaks (DSB), whereby the SSB/DSB ratio is shifted toward the DSB with increasing LET. For the DNA-incorporated Auger electron emitter Iodine-125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593687419ee5eb4e0e48439950b33cf7
https://doi.org/10.1080/09553002.2020.1851059
https://doi.org/10.1080/09553002.2020.1851059
Autor:
Shad R. Morton, Patrick Ostheim, Simone Schüle, Lovisa Waldner, T. Szatmári, Rita Hargitai, Christophe Badie, Elizabeth A. Ainsbury, Shanaz A. Ghandhi, Ursula Oestreicher, Andrzej Wojcik, Grainne O’Brien, Y. Ristic, Dominik Oskamp, Marcus Unverricht-Yeboah, Matthias Port, Ulrike Kulka, Kamil Brzóska, Igor Shuryak, Michael Abend, Sally A. Amundson, C. Bassinet, François Trompier, C. Siebenwirth, Katalin Lumniczky, Enikő Kis, Ralf Kriehuber
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Large-scale radiation emergency scenarios involving protracted low dose rate radiation exposure (e.g. a hidden radioactive source in a train) necessitate the development of high throughput methods for providing rapid individual dose estimates. During
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2fe50c6d99ff473dcb5d370c63890e
https://pubmed.ncbi.nlm.nih.gov/33963206
https://pubmed.ncbi.nlm.nih.gov/33963206
Autor:
Ralf Kriehuber, Thorsten Klawonn, Henner Hollert, Martina Fenske, Christoph Schäfers, Laura Sonnack
Publikováno v:
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics. 25:99-108
Metal toxicity is a global environmental challenge. Fish are particularly prone to metal exposure, which can be lethal or cause sublethal physiological impairments. The objective of this study was to investigate how adverse effects of chronic exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ec977ea789498d6360c871fe923ab9
https://doi.org/10.1016/j.cbd.2017.12.001
https://doi.org/10.1016/j.cbd.2017.12.001
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 823:58-64
Triplex-Forming oligonucleotides (TFO) bind sequence-specific to the DNA double helix in-vitro and in-vivo and are a promising tool to manipulate genes or gene regulatory elements. TFO as a carrier molecule for short-range particle emitter such as Au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efbd187f30b264b80bf6a6ab5488441
https://doi.org/10.1016/j.mrgentox.2017.09.002
https://doi.org/10.1016/j.mrgentox.2017.09.002
Autor:
Kristina Bannik, Sonja Strunz, Martin Stuschke, Ali Sak, Dennis Kübler, Ralf Kriehuber, Michael Groneberg
Publikováno v:
International Journal of Radiation Biology. 93:494-506
To uncover the role of EZH2 and its opponent ASHL2, a polycomb and trithorax group protein, respectively, on the radioresponsiveness of glioma cell lines.Expression of EZH2 and ASHL2 was inhibited by siRNA in glioma cell lines. The effect on histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1af2cb0574e0e76132bc87eae30d2b
https://doi.org/10.1080/09553002.2017.1270472
https://doi.org/10.1080/09553002.2017.1270472
Publikováno v:
Future Oncology. 12:617-624
Aim: To identify predictive assays for radiation-induced toxicity in prostate cancer patients. Patients & methods: Patients have been surveyed prospectively before and up to 16 months after radiotherapy using a validated questionnaire. Subgroups of 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542a7927e08cc09156c4a0c5906e38bb
https://doi.org/10.2217/fon.15.334
https://doi.org/10.2217/fon.15.334
Publikováno v:
Journal of radiation research 59(4), 411–429 (2018). doi:10.1093/jrr/rry038
Journal of Radiation Research
Journal of Radiation Research
Gene expression analysis was carried out in Jurkat cells in order to identify candidate genes showing significant gene expression alterations allowing robust discrimination of the Auger emitter $^{123}$I, incorporated into the DNA as $^{123}$I-iodode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::28f055b52e7c2765952f8076d39cb889
https://juser.fz-juelich.de/record/845520
https://juser.fz-juelich.de/record/845520
Publikováno v:
International Journal of Developmental Neuroscience. 48:9-17
BCL-2 is a multifunctional protein involved in the regulation of apoptosis, cell cycle progression and neural developmental processes. Its function in the latter process is not well understood and needs further elucidation. Therefore, we characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67865f20b9ff28485f4935986522ea6
https://doi.org/10.1016/j.ijdevneu.2015.10.004
https://doi.org/10.1016/j.ijdevneu.2015.10.004