Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Ralf, Grossmann"'
1
Platelet proinflammatory activity in clinically stable patients with CF starts in early childhood
Autor: Ralf Grossmann, Corinne Koenig, Helge Hebestreit, Ulrich Walter, Alexander Sturm
Publikováno v: Journal of Cystic Fibrosis. 9:179-186
Background Early onset chronic inflammation is present in CF. Platelets may contribute to inflammation by cytokine release and interaction with leukocytes. Methods Parameters of platelet proinflammatory function (soluble CD62P, soluble CD40L, the per
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56ccdfd516ba5c71c86aa0ed2a7a7a5
https://doi.org/10.1016/j.jcf.2009.12.004
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2
Decreased platelet reactivity identified by whole blood flow cytometry in Fanconi anaemia patients
Autor: Ana Gabriela Sitaru, Susanne Holzhauer, Helmut Hanenberg, Johannes Wirbelauer, Ralf Grossmann, Wolfram Ebell, Detlev Schindler, Ulrich Walter
Publikováno v: Thrombosis and Haemostasis. 98:1291-1297
Fanconi anaemia (FA) is a rare inherited chromosome instability disorder characterized by congenital anomalies and a high risk for bone marrow failure and cancer. Bleeding is a frequent complication in FA, leading to substantial morbidity and mortali
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72c3f7e947acfc0c33849358551681fa
https://doi.org/10.1160/th07-06-0426
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3
Neonatal platelets from cord blood and peripheral blood
Autor: Christian P. Speer, D. Singer, Ulrich Walter, A. Obergfell, S. Holzhauer, Ana Gabriela Sitaru, Ralf Grossmann
Publikováno v: Platelets. 16:203-210
The haemostatic system in neonates is different from that of adults, possibly contributing to an increased incidence of bleeding disorders, such as intracranial hemorrhage. In this study, we analyzed platelets from cord blood and peripheral blood, co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5641c2c697e158596916a36a02c92f2
https://doi.org/10.1080/09537100400016862
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4
Chorioamnionitis is associated with increased CD40L expression on cord blood platelets
Autor: Ulrich Walter, Ana-Gabriela Sitaru, Achim Obergfell, Susanne Holzhauer, Ralf Grossmann, Christian P. Speer
Publikováno v: Thrombosis and Haemostasis. 94:1219-1223
SummaryChorioamnionitis (CA) is a severe infection responsible not only for premature birth but also for many severe neonatal diseases. The aim of the present study was to investigate the expression of CD40L and P-selectin on platelets and the plasma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb02a60e1a2e7c5c334cccfcffd7b3cd
https://doi.org/10.1160/th05-02-0127
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5
Variable extent of clopidogrel responsiveness in patients after coronary stenting
Autor: Olga Sokolova, Achim Obergfell, Martin Eigenthaler, Axel Schnurr, Björn Lengenfelder, Ulrich Walter, Ralf Grossmann, Andreas Bonz, Christian Porsche
Publikováno v: Thrombosis and Haemostasis. 92:1201-1206
SummaryClopidogrel is an effective and specific inhibitor of ADP-induced platelet aggregation. After metabolic activation, the active clopidogrel metabolite irreversibly impairs the human platelet P2Y12 ADP receptor. Gialpha-protein activation and in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0859858ad8ad22f2ef6d8a446528980
https://doi.org/10.1160/th04-01-0049
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6
High factor VIII (FVIII) levels in venous thromboembolism: role of unbound FVIII
Autor: Kathleen Teuchert, Alois Spahn, Mario Berger, Christian M. Schambeck, Ralf Grossmann, Ulrich Walter, Sarah Zonnur
Publikováno v: Thrombosis and Haemostasis. 92:42-46
SummaryTheoretically, von Willebrand factor (VWF) should be capable of binding all factor VIII (FVIII), but an unbound FVIII (uFVIII) plasma fraction remains. In patients’ status post deep-vein thrombosis (DVT), an altered uFVIII fraction and high
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adee9cb815df7e9c363acdb6947c621
https://doi.org/10.1160/th04-02-0063
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8
The Impact of Dalteparin (Fragmin®) on Thrombin Generation in Pregnant Women with Venous Thromboembolism: Significance of the Factor V Leiden Mutation
Autor: Edda Eberl, Franz Keller, Ulrich Geisen, Christian M. Schambeck, Ralf Grossmann
Publikováno v: Thrombosis and Haemostasis. 85:782-786
SummaryHypercoagulability is observed in patients with inherited thrombophilia, e.g. factor V Leiden (FVL) mutation. Pregnancy represents a hypercoagulable state as well. This study addresses the effects of the FVL mutation on haemostatic activation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b954611f519812cbce8fb72ca33ab484
https://doi.org/10.1055/s-0037-1615718
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9
Hirudin treatment for multiple thromboses in a preterm infant with inherited thrombophilia
Autor: Christian P. Speer, Johannes Wirbelauer, Alexander Sturm, Ralf Grossmann
Publikováno v: Blood Coagulation & Fibrinolysis. 18:381-383
Thromboembolic events in preterm infants constitute a serious problem in neonatal intensive care. In most cases, treatment with low-molecular-weight heparin offers a sufficient therapy of thrombotic events. We report the case of a severely sick male
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29b2da15aa443b9903f7b6a5fbc465e
https://doi.org/10.1097/mbc.0b013e3281139c44
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