Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Raleigh D Kladney"'
Autor:
Julie A Wallace, Fu Li, Subhasree Balakrishnan, Carmen Z Cantemir-Stone, Thierry Pecot, Chelsea Martin, Raleigh D Kladney, Sudarshana M Sharma, Anthony J Trimboli, Soledad A Fernandez, Lianbo Yu, Thomas J Rosol, Paul C Stromberg, Robert Lesurf, Michael Hallett, Morag Park, Gustavo Leone, Michael C Ostrowski
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71533 (2013)
Tumor fibroblasts are active partners in tumor progression, but the genes and pathways that mediate this collaboration are ill-defined. Previous work demonstrates that Ets2 function in stromal cells significantly contributes to breast tumor progressi
Externí odkaz:
https://doaj.org/article/0d4bcc502f7c4211a33d43fcc4b6843f
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42005 (2012)
Osteoclasts are terminally differentiated cells that attach to bone and secrete proteases to degrade the bone matrix. The primary protease responsible for the degradation of the organic component of the bone matrix is Cathepsin K, which was largely t
Externí odkaz:
https://doaj.org/article/7855893af56740ffb4f0446e434de3eb
Autor:
Gina M. Sizemore, Subhasree Balakrishnan, Katie A. Thies, Anisha M. Hammer, Steven T. Sizemore, Anthony J. Trimboli, Maria C. Cuitiño, Sarah A. Steck, Gary Tozbikian, Raleigh D. Kladney, Neelam Shinde, Manjusri Das, Dongju Park, Sarmila Majumder, Shiva Krishnan, Lianbo Yu, Soledad A. Fernandez, Arnab Chakravarti, Peter G. Shields, Julia R. White, Lisa D. Yee, Thomas J. Rosol, Thomas Ludwig, Morag Park, Gustavo Leone, Michael C. Ostrowski
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The tumor microenvironment influences tumor progression. Here the authors show that lack of stromal PTEN phosphatase induces DNA repair defects in the neighboring mammary gland epithelial cells via hyperactivation of EGF-receptor signaling, resulting
Externí odkaz:
https://doaj.org/article/f4113fd816a74125b1e376f6cb322dab
Autor:
Loren S. Michel, Christine H. Chung, Jason D. Weber, Jeffrey M. Arbeit, Raleigh D. Kladney, James Lewis, Peter Humphrey, Ryan Day, Yiyu Dong, Aimin Li, Dorota Grabowska, Kaihua Zhang, Jianbo Wang
PDF file - 264K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cce78bbe92d3d54962c63e851f0ba28
https://doi.org/10.1158/1541-7786.22519048
https://doi.org/10.1158/1541-7786.22519048
Autor:
Loren S. Michel, Christine H. Chung, Jason D. Weber, Jeffrey M. Arbeit, Raleigh D. Kladney, James Lewis, Peter Humphrey, Ryan Day, Yiyu Dong, Aimin Li, Dorota Grabowska, Kaihua Zhang, Jianbo Wang
Trop2, an oncogenic cell surface protein under investigation as a therapeutic target, is commonly overexpressed in several epithelial tumor types yet its function in tumor biology remains relatively unexplored. To investigate the role of Trop2 in epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1044bfb33d2227e1ae9b0a320941d42d
https://doi.org/10.1158/1541-7786.c.6542266
https://doi.org/10.1158/1541-7786.c.6542266
Autor:
Thomas Ludwig, Reena Shakya, Ashley Hadjis, Raleigh D. Kladney, Gina M. Sizemore, Young-Jun Jeon, Christopher S. Koivisto, Peng Ru, Dan Jones, Stephen M. Bergin, Dongju Park
Notch1 mutations detected by exome sequencing from Brca1L1363P/ L1363P; p53+/+ thymic tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3622c3ef07ef6a0f78ab374b9501284
https://doi.org/10.1158/0008-5472.22426206.v1
https://doi.org/10.1158/0008-5472.22426206.v1
Autor:
Thomas Ludwig, Reena Shakya, Ashley Hadjis, Raleigh D. Kladney, Gina M. Sizemore, Young-Jun Jeon, Christopher S. Koivisto, Peng Ru, Dan Jones, Stephen M. Bergin, Dongju Park
Brca1L1363P mutant protein is capable of interacting with Bach1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a3121d14144b0989a621e009021061
https://doi.org/10.1158/0008-5472.22426209
https://doi.org/10.1158/0008-5472.22426209
Autor:
Karuppaiyah Selvendiran, David E. Cohn, Paul J. Goodfellow, Beth Y. Karlan, Jenny Lester, Raleigh D. Kladney, Jason Bice, Ross A. Wanner, Kristin Bixel, John J. Wallbillich, Shan Naidu, Adrian A. Suarez, Uksha Saini
Role of STAT3 in high-grade serous carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926520b2e3b6b615d22283e84174f23e
https://doi.org/10.1158/0008-5472.22417608
https://doi.org/10.1158/0008-5472.22417608
Autor:
Karuppaiyah Selvendiran, David E. Cohn, Paul J. Goodfellow, Beth Y. Karlan, Jenny Lester, Raleigh D. Kladney, Jason Bice, Ross A. Wanner, Kristin Bixel, John J. Wallbillich, Shan Naidu, Adrian A. Suarez, Uksha Saini
The initial molecular events that lead to malignant transformation of the fimbria of the fallopian tube (FT) through high-grade serous ovarian carcinoma (HGSC) remain poorly understood. In this study, we report that increased expression of signal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f80fef7698636d5b3a64935f7a2774
https://doi.org/10.1158/0008-5472.c.6509886.v1
https://doi.org/10.1158/0008-5472.c.6509886.v1
Autor:
Raphael E. Pollock, Carlo M. Croce, Dina Lev, Gustavo Leone, Raleigh D. Kladney, James L. Chen, Pierluigi Gasparini, Gonzalo Lopez, Francesca Lovat, Paolo Fadda, Kate Lynn Bill, Danielle A. Braggio, Abeba Zewdu, O. Hans Iwenofu, Kara Batte, Michele Guescini, Chad J. Creighton, Federica Calore, Lucia Casadei
Supplementary Table S1. Detailed information about patients (A) and control group (B)used in the discovery set; Supplementary Table S2. Detailed information about patients (A) and control group (B) used in the validation set; Supplementary Table S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bb966ed7b67345358d76c1b1550a64
https://doi.org/10.1158/0008-5472.22415402
https://doi.org/10.1158/0008-5472.22415402