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Autor:
Vaidya Jayathirtha Rao, Vanammoole Lakshmi Reddy, Parvathaneni Sai Prathima, Raktani Bikshapathi
Publikováno v:
New Journal of Chemistry. 42:20152-20155
The present work describes an expedient approach for the direct conversion of indole-3-carboxaldehyde to 3-chlorooxindoles using a simple sustainable synthetic method. From an environmental perspective, a combination of NaCl/oxone in a CH3CN : H2O (1
Autor:
Pamanji Rajesh, Vaidya Jayathirtha Rao, Nanubolu Jagadeesh, Gangasani Jagadeesh Kumar, Parvathaneni Sai Prathima, Janapala Venkateswara Rao, Raktani Bikshapathi, B. Yashwanth
Publikováno v:
Research on Chemical Intermediates. 44:553-565
The highly efficient and eco-economical “on water” method has been developed for the rapid construction of highly functionalized Baylis–Hillman derived piperazine derivatives (n = 34) in excellent yields under mild, catalyst-free reaction condi
Autor:
Thatikonda Narendar Reddy, Mettu Ravinder, Vaidya Jayathirtha Rao, Raktani Bikshapathi, Pombala Sujitha, C. Ganesh Kumar
Publikováno v:
Medicinal Chemistry Research. 26:2832-2844
A series of pyran derivatives (5–27) were synthesized in good yields by utilizing Baylis–Hillman chemistry and were further investigated for their in vitro anticancer, antibacterial, and antifungal activities. Most of the tested compounds exhibit
Publikováno v:
Green Chemistry. 19:4446-4450
This paper describes an atom-economical strategy for the direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes under metal free conditions with excellent functional group tolerance. The use of stable-nontoxic Oxone as a terminal oxida
Autor:
Wang, Hongdan, Liu, Yang, Yu, Jianmin, Luo, Yongguang, Wang, Lingling, Yang, Taehun, Raktani, Bikshapathi, Lee, Hyoyoung
Publikováno v:
ACS Applied Materials & Interfaces; 1/19/2022, Vol. 14 Issue 2, p3559-3567, 9p
Autor:
Raktani Bikshapathi, R. Maheshwari, G. Jagadeeshkumar, Rajesh Pamanji, U. S. N. Murty, V. Jayathirtha Rao, B. Yashwanth, J. Venkateswara Rao, Parvathaneni Sai Prathima
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 148:757-764
A series of C(3)-trifluoromethylated compounds derived from N-substituted isatins were synthesized. The biological activity of all 3-hydroxy-3-(trifluoromethyl)indolin-2-one derivatives have been evaluated for in vitro cytotoxic activity and antibact
Publikováno v:
New Journal of Chemistry. 40:10300-10304
An efficient, environmentally benign, eco-friendly protocol for selective oxidation of primary and secondary Baylis–Hillman alcohols to the corresponding carbonyl compounds has been developed. We have demonstrated the catalytic use of o-iodoxybenzo
Autor:
V. Jayathirtha Rao, P. Sai Prathima, Raktani Bikshapathi, G. Jagadeesh Kumar, Yedla Poornachandra, V. Himabindu, N. Jagadeesh, C. Ganesh Kumar
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 17
BACKGROUND Alkynes are fundamental building blocks in synthetic chemistry with high pharmaceutical applications. Among the bioactive acetylenic molecules, propargylic alcohol is most important as almost all the marketed drugs contains quaternary cent