CD26 ^low PD-1 ⁺ CD8 T cells are terminally exhausted and associated with leukemia progression in acute myeloid leukemia.

Autor: Zhou H; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States.; Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fujian Medical Center of Hematology, Fuzhou, China., Jia B; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Annageldiyev C; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Minagawa K; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Zhao C; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Mineishi S; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Ehmann WC; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Naik SG; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Cioccio J; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Wirk B; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Songdej N; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Rakszawski KL; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Nickolich MS; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States., Shen J; Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fujian Medical Center of Hematology, Fuzhou, China., Zheng H; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA, United States.; Department of Microbiology and Immunology, Penn State University College of Medicine, Hershey, PA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Jun 29; Vol. 14, pp. 1169144. Date of Electronic Publication: 2023 Jun 29 (Print Publication: 2023).

Post-transplant cyclophosphamide alters immune signatures and leads to impaired T cell reconstitution in allogeneic hematopoietic stem cell transplant.

Autor: Zhao C; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Bartock M; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Jia B; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Shah N; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Claxton DF; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Wirk B; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Rakszawski KL; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Nickolich MS; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Naik SG; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Rybka WB; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Ehmann WCC; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Hohl RJ; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Valentin J; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Bernas-Peterson M; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Gerber EM; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Zimmerman M; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Mierski JA; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Mineishi S; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA., Zheng H; Penn State Cancer Institute, Penn State University College of Medicine, 500 University Dr, PO Box 850, Hershey, PA, 17033, USA. hzheng@pennstatehealth.psu.edu.

Publikováno v: Journal of hematology & oncology [J Hematol Oncol] 2022 May 19; Vol. 15 (1), pp. 64. Date of Electronic Publication: 2022 May 19.

Eomes ⁺ T-bet ^low CD8 ⁺ T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid Leukemia.

Autor: Jia B; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Zhao C; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania.; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China., Rakszawski KL; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Claxton DF; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Ehmann WC; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Rybka WB; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Mineishi S; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Wang M; Department of Public Health Sciences, Penn State University College of Medicine, Hershey, Pennsylvania., Shike H; Department of Pathology, Penn State University College of Medicine, Hershey, Pennsylvania., Bayerl MG; Department of Pathology, Penn State University College of Medicine, Hershey, Pennsylvania., Sivik JM; Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania., Schell TD; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania.; Department of Microbiology and Immunology, Penn State University College of Medicine, Hershey, Pennsylvania., Drabick JJ; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Hohl RJ; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania., Zheng H; Penn State Cancer Institute, Penn State University College of Medicine, Hershey, Pennsylvania. hzheng@pennstatehealth.psu.edu.; Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Publikováno v: Cancer research [Cancer Res] 2019 Apr 01; Vol. 79 (7), pp. 1635-1645. Date of Electronic Publication: 2019 Feb 01.

Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.

Autor: Brown TJ; Department of Medicine, University of Texas Southwestern Medical Center, Dallas., Brennan MC; Ann Barshinger Cancer Center, Lancaster General Health, Lancaster, Pennsylvania., Li M; Department of Neurosurgery, University of Rochester Medical Center, Pittsford, New York., Church EW; Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Brandmeir NJ; Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Rakszawski KL; Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Patel AS; Department of Neurosurgery, Swedish Cerebrovascular Institute, Seattle, Washington., Rizk EB; Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania., Suki D; Division of Surgery, Department of Neurosurgery, University of Texas MD Anderson Cancer Center, Houston., Sawaya R; Division of Surgery, Department of Neurosurgery, University of Texas MD Anderson Cancer Center, Houston., Glantz M; Department of Neurosurgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Publikováno v: JAMA oncology [JAMA Oncol] 2016 Nov 01; Vol. 2 (11), pp. 1460-1469.