Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rakshit S. Tanna"'
Autor:
John D. Clarke, Sabrina M. Judson, Dan‐Dan Tian, Trevor O. Kirby, Rakshit S. Tanna, Adrienn Matula‐Péntek, Miklós Horváth, Matthew E. Layton, John R. White, Nadja B. Cech, Kenneth E. Thummel, Jeannine S. McCune, Danny D. Shen, Mary F. Paine
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1779-1790 (2023)
Abstract Green tea is a popular beverage worldwide. The abundant green tea catechin (−)‐epigallocatechin gallate (EGCG) is a potent in vitro inhibitor of intestinal UDP‐glucuronosyltransferase (UGT) activity (Ki ~2 μM). Co‐consuming green te
Externí odkaz:
https://doaj.org/article/3dfbcc53952945d38b75f821bdee7633
Autor:
Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Preston K. Manwill, Laura Flores-Bocanegra, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 620 (2022)
Increasing use of the botanical kratom to self-manage opioid withdrawal and pain has led to increased kratom-linked overdose deaths. Despite these serious safety concerns, rigorous fundamental pharmacokinetic knowledge of kratom in humans remains lac
Externí odkaz:
https://doaj.org/article/695db9b4d5e444cca0a9e8858c495f96
Autor:
Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:1315-1325
Autor:
Nadja B. Cech, Scott E. Hemby, Laura Flores-Bocanegra, Manead Khin, Rakshit S. Tanna, Nicholas H. Oberlies, Joshua J. Kellogg, E. D. Wallace, Daniel A. Todd, Huzefa A. Raja, Mary F. Paine, Tyler N. Graf, Scot McIntosh
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly controversial. Kratom produces more than 40 structurally related alkaloids, but most studies have focused on just two of these, mitragynine and 7-hydroxymitragynin
Autor:
Kenneth E. Thummel, Mary F. Paine, Rakshit S. Tanna, Allan E. Rettie, Dan-Dan Tian, Nadja B. Cech, Nicholas H. Oberlies
Publikováno v:
J Pharmacol Exp Ther
Preparations from the leaves of the kratom plant (Mitragyna speciosa) are consumed for their opioid-like effects. Several deaths have been associated with kratom used concomitantly with some drugs. Pharmacokinetic interactions are potential underlyin
Autor:
Deena L. Hadi, Rakshit S. Tanna, Jashvant D. Unadkat, Mary F. Paine, Nadja B. Cech, Sumit Bansal, Justina C. Calamia, Matthew E. Layton, Kenneth E. Thummel, Dan-Dan Tian, Miklós Horváth, Christopher M. Arian, Bálint Molnár, Joshua J. Kellogg, Laura M. Shireman, John R. White, James Nguyen, Richard D. Boyce
Publikováno v:
Clin Pharmacol Ther
The botanical natural product goldenseal can precipitate clinical drug interactions by inhibiting cytochrome P450 (CYP) 3A and CYP2D6. Besides P-glycoprotein, effects of goldenseal on other clinically relevant transporters remain unknown. Established
Autor:
Mary F. Paine, Kenneth E. Thummel, Dan-Dan Tian, Justina C. Calamia, Allan E. Rettie, Rakshit S. Tanna, Matthew G. McDonald
Publikováno v:
The FASEB Journal. 33
Background ldenseal is a botanical natural product commonly used to self-treat the common cold and various digestive ailments. Major constituents of goldenseal include the alkaloids berberine, (−)-...
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S60
Autor:
Mary F. Paine, Dan-Dan Tian, Nadja B. Cech, Rakshit S. Tanna, James Nguyen, Nicholas H. Oberlies
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S47