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Characterization of RNA editing and gene therapy with a compact CRISPR-Cas13 in the retina.

Autor: Kumar S; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, VIC 3002, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS 7000, Australia., Hsiao YW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia., Wong VHY; Department of Optometry and Vision Sciences, University of Melbourne, Parkville, VIC 3052, Australia., Aubin D; School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW 2050, Australia.; Stem Cell Medicine and Stem Cell and Organoid Facility, Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia., Wang JH; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia., Lisowski L; Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia.; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine - National Research Institute, Warsaw 04-349, Poland.; Australian Genome Therapeutics Centre, Children's Medical Research Institute and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia., Rakoczy EP; Centre for Ophthalmology and Visual Science, University of Western Australia, Crawley, WA 6009, Australia., Li F; Eye Center, Zhongshan City People's Hospital, Zhongshan, Guangdong Province 528403, China., Alarcon-Martinez L; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, VIC 3002, Australia., Gonzalez-Cordero A; School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW 2050, Australia.; Stem Cell Medicine and Stem Cell and Organoid Facility, Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia., Bui BV; Department of Optometry and Vision Sciences, University of Melbourne, Parkville, VIC 3052, Australia., Liu GS; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, VIC 3002, Australia.; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS 7000, Australia.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 05; Vol. 121 (45), pp. e2408345121. Date of Electronic Publication: 2024 Oct 30.

SGLT1/2 inhibition improves glycemic control and multi-organ protection in type 1 diabetes.

Autor: Herat LY; Dobney Hypertension Centre, School of Biomedical Sciences - Royal Perth Hospital Unit / Royal Perth Hospital Medical Research Foundation, University of Western Australia, Crawley, WA 6009, Australia., Matthews JR; Dobney Hypertension Centre, School of Biomedical Sciences - Royal Perth Hospital Unit / Royal Perth Hospital Medical Research Foundation, University of Western Australia, Crawley, WA 6009, Australia., Hibbs M; Research Centre, Royal Perth Hospital, Perth, WA 6000, Australia., Rakoczy EP; Department of Molecular Ophthalmology, University of Western Australia, Crawley, WA 6009, Australia., Schlaich MP; Dobney Hypertension Centre, Medical School - Royal Perth Hospital Unit / Royal Perth Hospital Medical Research Foundation, University of Western Australia, Crawley, WA 6009, Australia.; Department of Cardiology and Department of Nephrology, Royal Perth Hospital, Perth, WA 6000, Australia., Matthews VB; Dobney Hypertension Centre, School of Biomedical Sciences - Royal Perth Hospital Unit / Royal Perth Hospital Medical Research Foundation, University of Western Australia, Crawley, WA 6009, Australia.

Publikováno v: IScience [iScience] 2023 Jul 03; Vol. 26 (8), pp. 107260. Date of Electronic Publication: 2023 Jul 03 (Print Publication: 2023).