Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rakhi Tyagi Kundu"'
Autor:
Peter J. Hotez, Rakesh Adhikari, Wen-Hsiang Chen, Yi-Lin Chen, Portia Gillespie, Nelufa Y. Islam, Brian Keegan, Rakhi Tyagi Kundu, Jungsoon Lee, Zhuyun Liu, Jason T. Kimata, Numan Oezguen, Jeroen Pollet, Cristina Poveda, Kay Razavi, Shannon E. Ronca, Ulrich Strych, Syamala R. Thimmiraju, Leroy Versteeg, Maria Jose Villar-Mondragon, Junfei Wei, Bin Zhan, Maria Elena Bottazzi
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 495-500 (2023)
Introduction The development of a yeast-expressed recombinant protein-based vaccine technology co-developed with LMIC vaccine producers and suitable as a COVID-19 vaccine for global access is described. The proof-of-concept for developing a SARS-CoV-
Externí odkaz:
https://doaj.org/article/9dc912870f71410b853d29ac8af90252
Autor:
Yi-Lin Chen, Ashley L. Marcinkiewicz, Tristan A. Nowak, Rakhi Tyagi Kundu, Zhuyun Liu, Ulrich Strych, Maria-Elena Bottazzi, Wen-Hsiang Chen, Yi-Pin Lin
Publikováno v:
Infect Immun
Transmitted by ticks, the bacterium Borrelia burgdorferi sensu lato (Bbsl) is the causative agent of Lyme disease (LD), the most common vector-borne disease in the Northern hemisphere. No effective vaccines are currently available. Bbsl produces the
Autor:
Rakhi Tyagi Kundu, Wen-Hsiang Chen, Mun Peak Nyon, Amadeo B. Biter, Peter J. Hotez, Ulrich Strych, Maria Elena Bottazzi, Mohan Vivekanandan Poongavanam, Zhuyun Liu
Publikováno v:
Journal of Pharmaceutical Sciences. 109:1673-1680
Cutaneous leishmaniasis is a neglected tropical disease caused by the parasite Leishmania and transmitted by sandflies. It has become a major health problem in many tropical and subtropical countries, especially in regions of conflict and political i
Autor:
Rakhi Tyagi Kundu, Ulrich Strych, Peter J. Hotez, Wen-Hsiang Chen, Shannon E. Ronca, Vikram Paradkar, Maria Jose Villar, Jeroen Pollet, Martin Reers, Cristina Poveda, Rakesh Adhikari, Brian Keegan, Leroy Versteeg, Jason T. Kimata, Jungsoon Lee, Portia M. Gillespie, Bin Zhan, Junfei Wei, Zhuyun Liu, Maria Elena Bottazzi, Brianna Lopez
Publikováno v:
bioRxiv
We conducted preclinical studies in mice using a yeast-produced SARS-CoV-2 RBD219-N1C1 subunit vaccine candidate formulated with aluminum hydroxide (alum) and CpG deoxynucleotides. This vaccine formulation is similar to one that entered advanced phas
Autor:
Jungsoon Lee, Rakhi Tyagi Kundu, Joanne Altieri Rivera, Bin Zhan, Wen-Hsiang Chen, Peter J. Hotez, Zhuyun Liu, Junfei Wei, Maria Elena Bottazzi, Rakesh Adhikari, Portia M. Gillespie, Ulrich Strych
Publikováno v:
Applied Microbiology and Biotechnology
Abstract A SARS-CoV-2 RBD219-N1C1 (RBD219-N1C1) recombinant protein antigen formulated on Alhydrogel® has recently been shown to elicit a robust neutralizing antibody response against SARS-CoV-2 pseudovirus in mice. The antigen has been produced und
Autor:
Brian Keegan, Jungsoon Lee, Bin Zhan, Maria Jose Villar, Rakhi Tyagi Kundu, Cristina Poveda, Joanne Altieri Rivera, Jeroen Pollet, Leroy Versteeg, Maria Elena Bottazzi, Ana Carolina de Araujo Leao, Zhuyun Liu, Ulrich Strych, Junfei Wei, Wen-Hsiang Chen, Peter J. Hotez, Portia M. Gillespie, Rakesh Adhikari
BackgroundCoronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has now spread worldwide to infect over 110 million people, with approximately 2.5 million reported deaths. A safe and effective vaccine remains urgently needed.MethodWe constructed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0814e5fc56dfb19aecfbe6fae352800b
https://doi.org/10.1101/2020.11.09.373449
https://doi.org/10.1101/2020.11.09.373449
Autor:
Ulrich Strych, Portia M. Gillespie, Maria Jose Villar, Leroy Versteeg, Jason T. Kimata, Jeroen Pollet, Jungsoon Lee, Zhuyun Liu, Yi-Lin Chen, Peter J. Hotez, Bin Zhan, Maria Elena Bottazzi, Rakesh Adhikari, Wen-Hsiang Chen, Cristina Poveda, Rakhi Tyagi Kundu, Aaron O. Bailey, Brian Keegan, Junfei Wei
Publikováno v:
Protein Expression and Purification
BackgroundSARS-CoV-2 protein subunit vaccines are being evaluated by multiple manufacturers to fill the need for low-cost, easy to scale, safe, and effective COVID-19 vaccines for global access. Vaccine candidates relying on the receptor-binding doma
Autor:
Wen-Hsiang Chen, Surafel Damena, Mun Peak Nyon, Peter J. Hotez, Zhuyun Liu, Amadeo B. Biter, Bin Zhan, Maria Elena Bottazzi, Rakhi Tyagi Kundu, Ulrich Strych
Publikováno v:
Protein expression and purification. 177
Cutaneous leishmaniasis is a parasitic and neglected tropical disease transmitted by the bites of sandflies. The emergence of cutaneous leishmaniasis in areas of war, conflict, political instability, and climate change has prompted efforts to develop
Autor:
Leroy Versteeg, Bin Zhan, Brian Keegan, Jungsoon Lee, Rakesh Adhikari, Wen-Hsiang Chen, Maria Elena Bottazzi, Joanne Altieri Rivera, Zhuyun Liu, Jeroen Pollet, Rakhi Tyagi Kundu, Maria Jose Villar, Portia M. Gillespie, Junfei Wei, Ulrich Strych, Peter J. Hotez, Cristina Poveda, Ana Carolina de Araujo Leao
Publikováno v:
Biochimica et Biophysica Acta. General Subjects
Background Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has now spread worldwide to infect over 110 million people, with approximately 2.5 million reported deaths. A safe and effective vaccine remains urgently needed. Method We constructe