Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rakhi, Pal"'
Autor:
Shreya Das Sharma, Bharath Kumar Reddy, Rakhi Pal, Tuula E. Ritakari, James D. Cooper, Bhuvaneish T. Selvaraj, Peter C. Kind, Siddharthan Chandran, David J.A. Wyllie, Sumantra Chattarji
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112344- (2023)
Summary: Pre-clinical studies of fragile X syndrome (FXS) have focused on neurons, with the role of glia remaining largely underexplored. We examined the astrocytic regulation of aberrant firing of FXS neurons derived from human pluripotent stem cell
Externí odkaz:
https://doaj.org/article/07393c8817104f9e9f38c64e50f84baa
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
There is accumulating evidence for contrasting patterns of stress-induced morphological and physiological plasticity in glutamatergic synapses of the hippocampus and amygdala. The same chronic stress that leads to the formation of dendritic spines in
Externí odkaz:
https://doaj.org/article/f8aa35c2073441d5aed2d918eb671824
Autor:
Shreya Das Sharma, Rakhi Pal, Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Nisha Raj, Krishna Kumar Samaga, Durga J. Srinivasan, Loren Ornelas, Dhruv Sareen, Matthew R. Livesey, Gary J. Bassell, Clive N. Svendsen, Peter C. Kind, Siddharthan Chandran, Sumantra Chattarji, David J. A. Wyllie
Publikováno v:
Molecular Autism, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Fragile X syndrome (FXS), a neurodevelopmental disorder, is a leading monogenetic cause of intellectual disability and autism spectrum disorder. Notwithstanding the extensive studies using rodent and other pre-clinical models of F
Externí odkaz:
https://doaj.org/article/be1ddd0d597d4f079af05cef176f7f96
Autor:
Michelle Ninochka D'Souza, Naveen Kumar Chandappa Gowda, Vishal Tiwari, Rosana Ottakandathil Babu, Praveen Anand, Sudhriti Ghosh Dastidar, Randhir Singh, Owen G. James, Bhuvaneish Selvaraj, Rakhi Pal, Arati Ramesh, Sumantra Chattarji, Siddharthan Chandran, Akash Gulyani, Dasaradhi Palakodeti, Ravi S. Muddashetty
Publikováno v:
iScience, Vol 9, Iss , Pp 399-411 (2018)
Summary: FMRP is an RNA-binding protein that is known to localize in the cytoplasm and in the nucleus. Here, we have identified an interaction of FMRP with a specific set of C/D box snoRNAs in the nucleus. C/D box snoRNAs guide 2’O methylations of
Externí odkaz:
https://doaj.org/article/cb878e62eeb44157894b15aa761e47cc
The Covid-19 disease has been so destructive to mankind that millions around the world have perished all across the world since it first emerged. Everyone was confined in their homes as a result of the shutdown, and all essential organizations and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b8d667904b9a7c41286041f6840e7d
Autor:
Rakhi Pal, Aditi Bhattacharya
Publikováno v:
Brain Sciences, Vol 9, Iss 3, p 59 (2019)
The most conserved molecular phenotype of Fragile X Syndrome (FXS) is aberrant protein synthesis. This has been validated in a variety of experimental model systems from zebrafish to rats, patient-derived lymphoblasts and fibroblasts. With the advent
Externí odkaz:
https://doaj.org/article/f3cb44e9d0df497fa8b981695ab40963
Autor:
Devendra K. Agrawal, Samad Ahadian, Ajoy Aloysius, P.R. Anil Kumar, Sudha Anjali, Veena B. Antony, S. Arya, Aleksandra Benko, Marco Cícero Bottino, Soumya K. Chandrasekhar, Thomas Chandy, John Lalith Charles Richard, Huizhi Chen, Smitha Chenicheri, Jorge L. Cholula-Díaz, Eva C. Das, Madhusmita Dash, Kevin G. Dsouza, Gregory R.D. Evans, Renjitha Gopurappilly, Lianxian Guo, Gerardo Hernandez-Moreno, Johnson V. John, Maji Jose, Arun Jyothidasan, Ajay Kashi, Gilson Khang, Wooyoup Kim, Manoj Komath, Dae Hoon Lee, Jianqiang Liu, S. Sharareh Mahdavi, João Mano, Shohreh Mashayekhan, Alec McCarthy, David Medina-Cruz, L.P. Merlin Rajesh Lal, Ebrahim Mostafavi, Jahnavi Mudigonda, Eliseu Aldrighi Münchow, Sara Nadine, Anaga Nair, Deepthi S. Rajendran Nair, Rajasekaran Namakkal Soorappan, Himansu Sekhar Nanda, Joshi C. Ouseph, Rakhi Pal, Rakesh Pemmada, Xinsheng Peng, Anitha Radhakrishnan, Abinayaa Rajkumar, Rajesh Ramachandran, Seeram Ramakrishna, null Remya Kommeri, Rajalekshmi Resmi, Prosenjit Saha, Subrata Saha, Ramakrishna Perumal Saravana, Nisha Shankhwar, Chandra P. Sharma, Jeong Eun Song, Isaac Jordão de Souza Araújo, Sreekanth Sreekumaran, Sini Sunny, Ranu Surolia, Puneet Tandon, Nader Tanideh, Alexander M. Tatara, Vicky Subhash Telang, Finosh G. Thankam, Biju B. Thomas, Sabu Thomas, Vinoy Thomas, Saidah Tootla, Linh B. Truong, Aynur Unal, Vineeth M. Vijayan, Liyan Wang, Thomas J. Webster, Alan D. Widgerow, Jingwei Xie, Hui Zhou, Yubin Zhou, Mary E. Ziegler, Marta Zurek-Mortka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398851c0577c54af4721557358b1075c
https://doi.org/10.1016/b978-0-12-824064-9.09992-5
https://doi.org/10.1016/b978-0-12-824064-9.09992-5
Autor:
Rakhi Pal, Sumantra Chattarji, Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Shreya Das Sharma, Siddharthan Chandran, Peter C. Kind, Krishna Kumar Samaga, Loren Ornelas, Clive N. Svendsen, Durga Jeyalakshmi Srinivasan, Matthew R. Livesey, David J. A. Wyllie, Dhruv Sareen, Gary J. Bassell, Nisha Raj
Publikováno v:
Molecular Autism
Das Sharma, S, Pal, R, Reddy, B K, Thangaraj Selvaraj, B, Raj, N, Samaga, K K, Srinivasan, D J, Ornelas, L, Sareen, D, Livesey, M, Bassell, G J, Svendsen, C N, Kind, P, Chandran, S, Chattarji, S & Wyllie, D 2020, ' Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns ', Molecular Autism . https://doi.org/10.1186/s13229-020-00351-4
Molecular Autism, Vol 11, Iss 1, Pp 1-16 (2020)
Das Sharma, S, Pal, R, Reddy, B K, Thangaraj Selvaraj, B, Raj, N, Samaga, K K, Srinivasan, D J, Ornelas, L, Sareen, D, Livesey, M, Bassell, G J, Svendsen, C N, Kind, P, Chandran, S, Chattarji, S & Wyllie, D 2020, ' Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns ', Molecular Autism . https://doi.org/10.1186/s13229-020-00351-4
Molecular Autism, Vol 11, Iss 1, Pp 1-16 (2020)
Background Fragile X syndrome (FXS), a neurodevelopmental disorder, is a leading monogenetic cause of intellectual disability and autism spectrum disorder. Notwithstanding the extensive studies using rodent and other pre-clinical models of FXS, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bf30383810004edeb78b15be8ec53b
https://doi.org/10.1186/s13229-020-00351-4
https://doi.org/10.1186/s13229-020-00351-4
Autor:
N. K. Venkataramana, Rakhi Pal, Shailesh A. V. Rao, Arun L. Naik, Majahar Jan, Rahul Nair, C. C. Sanjeev, Ravindra B. Kamble, D. P. Murthy, Krishna Chaitanya
Publikováno v:
Stem Cells International, Vol 2012 (2012)
The progress of PD and its related disorders cannot be prevented with the medications available. In this study, we recruited 8 PD and 4 PD plus patients between 5 to 15 years after diagnosis. All patients received BM-MSCs bilaterally into the SVZ and
Externí odkaz:
https://doaj.org/article/17e4f6528fc0470daaf7395530ca703a