Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rakhee Bajaj"'
Autor:
Roxsan Manshouri, Etienne Coyaud, Samrat T. Kundu, David H. Peng, Sabrina A. Stratton, Kendra Alton, Rakhee Bajaj, Jared J. Fradette, Rosalba Minelli, Michael D. Peoples, Alessandro Carugo, Fengju Chen, Christopher Bristow, Jeffrey J. Kovacs, Michelle C. Barton, Tim Heffernan, Chad J. Creighton, Brian Raught, Don L. Gibbons
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Non-small cell lung cancer (NSCLC) is often associated with metastasis to the lungs. Here, the authors perform independent screens and identify NuRD as a co-repressor of ZEB1, and demonstrate TBC1D2b as a downstream target of ZEB1/NuRD complex regula
Externí odkaz:
https://doaj.org/article/175dfc318ac14591a1188315ed141a14
Publikováno v:
Cells, Vol 11, Iss 9, p 1484 (2022)
The Golgi apparatus is at the center of protein processing and trafficking in normal cells. Under pathological conditions, such as in cancer, aberrant Golgi dynamics alter the tumor microenvironment and the immune landscape, which enhances the invasi
Externí odkaz:
https://doaj.org/article/838f7dcb75bc4412896aec8f85a5bb1e
Autor:
Samrat T. Kundu, B. Leticia Rodriguez, Laura A. Gibson, Amanda N. Warner, Mabel G. Perez, Rakhee Bajaj, Jared J. Fradette, Caleb A. Class, Luisa M. Solis, Frank R. Rojas Alvarez, Ignacio I. Wistuba, Lixia Diao, Fengju Chen, Mohit Sachdeva, Jing Wang, David G. Kirsch, Chad J. Creighton, Don L. Gibbons
Publikováno v:
Genes & Development. 36:582-600
One of the mechanisms by which cancer cells acquire hyperinvasive and migratory properties with progressive loss of epithelial markers is the epithelial-to-mesenchymal transition (EMT). We have previously reported that in different cancer types, incl
Autor:
Samrat T. Kundu, Chad J. Creighton, Jared J. Fradette, Kenneth L. Scott, Caitlin L. Grzeskowiak, Rakhee Bajaj, Don L. Gibbons
Publikováno v:
Oncogene
Summary Non-small cell lung cancer (NSCLC) is the deadliest form of cancer worldwide, due in part to its proclivity to metastasize. Identifying novel drivers of invasion and metastasis holds therapeutic potential for the disease. We conducted a gain-
Lysosomal transmembrane protein TMEM106B alters TFEB signaling and the tumor immune microenvironment
Publikováno v:
Leading Edge of Cancer Research Symposium: Poster Session.
Autor:
Samrat T, Kundu, B Leticia, Rodriguez, Laura A, Gibson, Amanda N, Warner, Mabel G, Perez, Rakhee, Bajaj, Jared J, Fradette, Caleb A, Class, Luisa M, Solis, Frank R, Rojas Alvarez, Ignacio I, Wistuba, Lixia, Diao, Fengju, Chen, Mohit, Sachdeva, Jing, Wang, David G, Kirsch, Chad J, Creighton, Don L, Gibbons
Publikováno v:
Genesdevelopment. 36(9-10)
One of the mechanisms by which cancer cells acquire hyperinvasive and migratory properties with progressive loss of epithelial markers is the epithelial-to-mesenchymal transition (EMT). We have previously reported that in different cancer types, incl
Autor:
Rakhee Bajaj, B. Leticia Rodriguez, William K. Russell, Amanda N. Warner, Lixia Diao, Jing Wang, Maria G. Raso, Wei Lu, Khaja Khan, Luisa S. Solis, Harsh Batra, Ximing Tang, Jared F. Fradette, Samrat T. Kundu, Don L. Gibbons
Publikováno v:
Cell Reports. 40:111429
Lung cancer is a highly aggressive and metastatic disease responsible for approximately 25% of all cancer-related deaths in the United States. Using high-throughput in vitro and in vivo screens, we have previously established Impad1 as a driver of lu
Autor:
Jared J. Fradette, Rakhee Bajaj, Don L. Gibbons, Joshua K. Ochieng, Samrat T. Kundu, B. Leticia Rodriguez
Publikováno v:
Oncogene
Metastasis is the cause for 90% of cancer-related mortalities. Identification of genetic drivers promoting dissemination of tumor cells may provide opportunities for novel therapeutic strategies. We previously reported an in vivo gain-of-function scr