Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rakesh Suman"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Toxoplasma gondii is a widespread single-celled intracellular eukaryotic apicomplexan protozoan parasite primarily associated with mammalian foetal impairment and miscarriage, including in humans. Is estimated that approximately one third of the huma
Externí odkaz:
https://doaj.org/article/f405bf882426419988be7e8628e4e0d8
Autor:
Tess A. Stanly, Rakesh Suman, Gulab Fatima Rani, Peter J. O’Toole, Paul M. Kaye, Ian S. Hitchcock
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Platelets are specialized anucleate cells that play a major role in hemostasis following vessel injury. More recently, platelets have also been implicated in innate immunity and inflammation by directly interacting with immune cells and releasing pro
Externí odkaz:
https://doaj.org/article/31955ef5a9c6409ebffc1345a00b0a13
Autor:
Anna C. Roberts, Jai Gohil, Laura Hudson, Kyle Connolly, Philip Warburton, Rakesh Suman, Peter O’Toole, David J. O’Regan, Neil A. Turner, Kirsten Riches, Karen E. Porter
Publikováno v:
Journal of Diabetes Research, Vol 2015 (2015)
Type 2 diabetes (T2DM) confers increased risk of endothelial dysfunction, coronary heart disease, and vulnerability to vein graft failure after bypass grafting, despite glycaemic control. This study explored the concept that endothelial cells (EC) cu
Externí odkaz:
https://doaj.org/article/d82e69fbad2e40a69c3165dbc4a8a766
Autor:
Norman J. Maitland, Martin G. Rumsby, Daniel M. Berney, Sylvain G. Bourgoin, Karen Hogg, Amanda R. Noble, Rakesh Suman
Publikováno v:
British Journal of Cancer
BackgroundPhospholipases D1 and D2 (PLD1/2) are implicated in tumorigenesis through their generation of the signalling lipid phosphatidic acid and its downstream effects. Inhibition of PLD1 blocks prostate cell growth and colony formation. Here a rol
Autor:
Peter O'Toole, William J. Brackenbury, Michaela Nelson, Rakesh Suman, Ming Yang, Richard Kasprowicz, Andrew D. James
Publikováno v:
Journal of Cellular Physiology. 235:3950-3972
Ion channels can regulate the plasma membrane potential (Vm ) and cell migration as a result of altered ion flux. However, the mechanism by which Vm regulates motility remains unclear. Here, we show that the Nav 1.5 sodium channel carries persistent
Autor:
Ian S. Hitchcock, Rakesh Suman, Peter O'Toole, Gulab Fatima Rani, Paul M. Kaye, Tess A. Stanly
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
Platelets are specialized anucleate cells that play a major role in hemostasis following vessel injury. More recently, platelets have also been implicated in innate immunity and inflammation by directly interacting with immune cells and releasing pro
Cell cycle progression in the presence of damaged DNA can lead to accumulation of mutations and pose a risk for tumour development. In response to DNA damage in G2 phase, human cells can be forced to exit the cell cycle in a p53-p21- and APC/CCdh1-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a82e7ba7dd0f11341336a30ec3df92f
https://doi.org/10.1101/2020.06.09.141770
https://doi.org/10.1101/2020.06.09.141770
Autor:
Ming, Yang, Andrew D, James, Rakesh, Suman, Richard, Kasprowicz, Michaela, Nelson, Peter J, O'Toole, William J, Brackenbury
Publikováno v:
Journal of Cellular Physiology
Ion channels can regulate the plasma membrane potential (Vm) and cell migration as a result of altered ion flux. However, the mechanism by which Vm regulates motility remains unclear. Here, we show that the Nav1.5 sodium channel carries persistent in
Autor:
Peter O'Toole, Ming Yang, William J. Brackenbury, Michaela Nelson, Rakesh Suman, Andrew D. James, Richard Kasprowicz
Ion channels can regulate the plasma membrane potential (Vm) and cell migration as a result of altered ion flux. However, the mechanism by which Vm regulates motility remains unclear. Here, we show that the Nav1.5 sodium channel carries persistent in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c948804be4dc79330eedaea6262fe2d
Characterising live cell behaviour: Traditional label-free and quantitative phase imaging approaches
Publikováno v:
The international journal of biochemistrycell biology. 84
Label-free imaging uses inherent contrast mechanisms within cells to create image contrast without introducing dyes/labels, which may confound results. Quantitative phase imaging is label-free and offers higher content and contrast compared to tradit