Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Rakesh Radhakrishnan"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The distribution of dietary vitamin A/all-trans retinol/ROL throughout the body is critical for maintaining retinoid function in peripheral tissues and for retinoid delivery to the eye in the support of visual function. In the circulation, all-trans-
Externí odkaz:
https://doaj.org/article/97fc0a9c5ac44990a3c9a82c084fa015
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cytosolic ROS, generated by NADPH oxidase 2 (Nox2) in diabetes, damage retinal mitochondria, which leads to the development of retinopathy. A small molecular weight G-protein essential for Nox2 activation, Rac1, is also transcriptionally act
Externí odkaz:
https://doaj.org/article/ecd9541b00b64777b0106355a4ab418b
Autor:
Rakesh Radhakrishnan, Venkateshwara R. Dronamraju, Matthias Leung, Andrew Gruesen, Ashish K. Solanki, Stephen Walterhouse, Heidi Roehrich, Grace Song, Rafael da Costa Monsanto, Sebahattin Cureoglu, René Martin, Altaf A. Kondkar, Frederik J. van Kuijk, Sandra R. Montezuma, Hans-Joachim Knöelker, Robert B. Hufnagel, Glenn P. Lobo
Publikováno v:
Ophthalmic Genet
Rods and cones are photoreceptor neurons in the retina that are required for visual sensation in vertebrates, wherein the perception of vision is initiated when these neurons respond to photons in the light stimuli. The photoreceptor cell is structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8a0bf25792e0625591880e5b3829fd
https://doi.org/10.1080/13816810.2022.2062391
https://doi.org/10.1080/13816810.2022.2062391
Autor:
Rakesh, Radhakrishnan1 (AUTHOR), Chanana, Upasana Bedi1 (AUTHOR), Hussain, Saddam1 (AUTHOR), Sharma, Soni1 (AUTHOR), Goel, Kaveri1 (AUTHOR), Bisht, Deepa1 (AUTHOR), Patne, Ketki1 (AUTHOR), Swer, Pynskhem Bok1 (AUTHOR), Hockensmith, Joel W.2 (AUTHOR) rohini_m@mail.jnu.ac.in, Muthuswami, Rohini1 (AUTHOR) rohini_m@mail.jnu.ac.in
Publikováno v:
PLoS ONE. 5/17/2021, Vol. 16 Issue 5, p1-23. 23p.
Autor:
Rakesh Radhakrishnan, Matthias Leung, Heidi Roehrich, Stephen Walterhouse, Altaf A. Kondkar, Wayne Fitzgibbon, Manas R. Biswal, Glenn P. Lobo
Publikováno v:
Nutrients; Volume 14; Issue 12; Pages: 2371
The systemic transport of dietary vitamin A/all-trans retinol bound to RBP4 into peripheral tissues for storage is an essential physiological process that continuously provides visual chromophore precursors to the retina under fasting conditions. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9aa4a37ef1aec7cc5b237a83dcd61fd
https://pubmed.ncbi.nlm.nih.gov/35745101
https://pubmed.ncbi.nlm.nih.gov/35745101
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Rakesh Radhakrishnan, Renu A. Kowluru
Publikováno v:
Diabetes. 70:227-239
The retina experiences increased oxidative stress in diabetes, and the transcriptional activity of Nrf2, which is critical in regulating many antioxidant genes, is decreased. The nuclear movement/transcriptional activity of Nrf2 is mediated by its in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f257aea945d4ba7f876bd48d5776f1f4
https://doi.org/10.2337/db20-0375
https://doi.org/10.2337/db20-0375
Autor:
Kumaravel Mohankumar, Sankar Pajaniradje, Shamim Akhtar Sufi, Rukkumani Rajagopalan, Rakesh Radhakrishnan, Srividya Subramanian, Surya Prakash Rao Hulluru, Parthiban Anaikutti
Publikováno v:
Letters in Drug Design & Discovery. 17:1146-1154
Background: Drug resistance by the cancer cells towards current chemotherapeutic approaches poses a great challenge. In the present study, an indole analogue of a well-known plant derived anticancer molecule, curcumin, was tested for its Multidrug Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7ae8b4030536ea5f95ceb6d7dde1da5
https://doi.org/10.2174/1570180817666200402124503
https://doi.org/10.2174/1570180817666200402124503
Autor:
Altaf A. Kondkar, Taif A. Azad, Tahira Sultan, Rakesh Radhakrishnan, Essam A. Osman, Faisal A. Almobarak, Glenn P. Lobo, Saleh A. Al-Obeidan
Publikováno v:
Genes; Volume 13; Issue 3; Pages: 489
We investigated the association between DICER1 (rs3742330) and DROSHA (rs10719) polymorphisms and pseudoexfoliation glaucoma (PXG) and related clinical phenotypes in a Saudi cohort. In a retrospective case-control study, TaqMan real-time, PCR-based g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089dd481c9193eded5145fab7fb7ca0f
Publikováno v:
Nutrients, Vol 13, Iss 3987, p 3987 (2021)
Nutrients
Nutrients
Vitamins are essential compounds obtained through diet that are necessary for normal development and function in an organism. One of the most important vitamins for human physiology is vitamin A, a group of retinoid compounds and carotenoids, which g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38559f56617b3df55e2cda4bdc9d47f9
https://www.mdpi.com/2072-6643/13/11/3987
https://www.mdpi.com/2072-6643/13/11/3987