Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Rakesh K Arya"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundThe RIP1-RIP3-MLKL-mediated cell death pathway is associated with progression of non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH). Previous work identified a critical role for MLKL, the key effector regulating necroptosis, but
Externí odkaz:
https://doaj.org/article/b59b614ce2774f44987134d4f15e2a72
Autor:
Mushtaq A. Nengroo, Shrankhla Maheshwari, Akhilesh Singh, Ayushi Verma, Rakesh K. Arya, Priyank Chaturvedi, Krishan K. Saini, Anup K. Singh, Abhipsa Sinha, Sanjeev Meena, Annapurna Gupta, Anjali Mishra, Jayanta Sarkar, Dipak Datta
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-19 (2021)
Abstract Chemokine receptor CXCR4 overexpression in solid tumors has been strongly associated with poor prognosis and adverse clinical outcome. However, blockade of CXCL12-CXCR4 signaling axis by inhibitors like Nox-A12, FDA approved CXCR4 inhibitor
Externí odkaz:
https://doaj.org/article/2286ec9f26234bc5827773856373a7f7
Autor:
Dipak Datta, Koneni V. Sashidhara, Jiaur R. Gayen, Mohammad I. Siddiqi, Himangsu K. Bora, Mohammed Riyazuddin, Ruchir Kant, Anup K. Singh, Sanjeev Meena, Tanuj Sharma, Sudhir Shahi, Srikanth H. Cheruvu, Rakesh K. Arya, Gopala R. Palnati, L. Ravithej Singh, Akhilesh Singh, Srinivasa R. Avula, Shrankhla Maheshwari
SUPPLEMENTARY FIGURE S1: General information and rationale of synthesis of hybrid molecules of Chalcone and Semicarbazone SUPPLEMENTARY FIGURE S2: Detailed qualitative analysis of compounds of Chalcone and Semicarbazone hybrid series Supplementary Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628b9cafc6e1657c72659a9162691b6b
https://doi.org/10.1158/1535-7163.22508397.v1
https://doi.org/10.1158/1535-7163.22508397.v1
Publikováno v:
2022 IEEE Conference on Interdisciplinary Approaches in Technology and Management for Social Innovation (IATMSI).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9769b65d8c1a90636697c92b3640ceb4
https://doi.org/10.1109/iatmsi56455.2022.10119298
https://doi.org/10.1109/iatmsi56455.2022.10119298
Autor:
Mallika Mathur, Yu‐Te Yeh, Rakesh K. Arya, Long Jiang, Majid Pornour, Weiping Chen, Yinyan Ma, Bin Gao, Ling He, Zhekang Ying, Bingzhong Xue, Hang Shi, Youngshim Choi, Liqing Yu
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES.
Alcohol-associated liver disease (ALD) pathologies include steatosis, inflammation, and injury, which may progress to fibrosis, cirrhosis, and cancer. The liver receives ~60% of fatty acids from adipose tissue triglyceride hydrolysis, but the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b205be3ae3dd94c90bd54dae4bdbd38
https://pubmed.ncbi.nlm.nih.gov/35844150
https://pubmed.ncbi.nlm.nih.gov/35844150
Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells
Autor:
Achchhe Lal Vishwakarma, Shrankhla Maheshwari, Krishan Kumar Saini, Mushtaq Ahmad Nengroo, Dipak Datta, Kavita Singh, Ayushi Verma, Akhilesh Singh, Anup Kumar Singh, Rakesh K. Arya, Jayanta Sarkar, Priyank Chaturvedi
Publikováno v:
Epigenetics
Drug resistance is one of the trademark features of Cancer Stem Cells (CSCs). We and others have recently shown that paucity of functional death receptors (DR4/5) on the cell surface of tumour cells is one of the major reasons for drug resistance, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af68d55fd0c523502d6e0101a7627321
https://doi.org/10.1080/15592294.2020.1789270
https://doi.org/10.1080/15592294.2020.1789270
Autor:
Xiaoping Zhu, Rakesh K. Arya, Rishov Goswami, Shweta Sharma, Dimitar R. Stamov, Shaik O. Rahaman, Bidisha Dutta
Publikováno v:
Sci Signal
Implantation of biomaterials or devices into soft tissue often leads to the development of the foreign body response (FBR), an inflammatory condition that can cause implant failure, tissue injury, and death of the patient. Macrophages accumulate and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960d6c914c9372b70985f65968422536
https://doi.org/10.1126/scisignal.abd4077
https://doi.org/10.1126/scisignal.abd4077
Autor:
Dipak Datta, Rakesh K. Arya, Krishan Kumar Saini, Anup Kumar Singh, Sanjeev Meena, Akhilesh Singh, Ayushi Verma, Jayanta Sarkar, Priyank Chaturvedi, Annapurna Gupta, Abhipsa Sinha, Shrankhla Maheshwari, Anjali Mishra, Mushtaq Ahmad Nengroo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-19 (2021)
Cell Death & Disease
Cell Death & Disease
Chemokine receptor CXCR4 overexpression in solid tumors has been strongly associated with poor prognosis and adverse clinical outcome. However, blockade of CXCL12-CXCR4 signaling axis by inhibitors like Nox-A12, FDA approved CXCR4 inhibitor drug AMD3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e36c4bed58f1cf58abbc6374183defe
https://doi.org/10.1038/s41419-021-03730-8
https://doi.org/10.1038/s41419-021-03730-8
Autor:
Shikha Sharma, Archana Rastogi, Sukanya Sahu, Subasa Chandra Bishwal, Md. Zubbair Malik, Ranjan Kumar Nanda, Debasis Sahu, Sandeep Rai Kaushik, Seema Sharma, Shanta Sen, R. K. Singh, Ekta Saini, Rakesh K. Arya, Amulya K. Panda
Troxerutin (TXR) is a phytochemical reported to possess anti-inflammatory and hepatoprotective effects. In this study, we aimed to exploit anti-arthritic properties of TXR using an adjuvant induced arthritic (AIA) rat model. AIA induced rats showed h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d2bfc5793ff2fda6e5e92f3df49b6c
https://doi.org/10.21203/rs.3.rs-406279/v1
https://doi.org/10.21203/rs.3.rs-406279/v1
Publikováno v:
The Journal of Biological Chemistry
Multinucleated giant cells are formed by the fusion of macrophages and are a characteristic feature in numerous pathophysiological conditions including the foreign body response (FBR). Foreign body giant cells (FBGCs) are inflammatory and destructive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c314a48b2ae52b524233b9ecf265d89
https://pubmed.ncbi.nlm.nih.gov/33262217
https://pubmed.ncbi.nlm.nih.gov/33262217