Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rakesh Bodhicharla"'
Autor:
Kathleen A. Hershberger, John P. Rooney, Elena A. Turner, Lauren J. Donoghue, Rakesh Bodhicharla, Laura L. Maurer, Ian T. Ryde, Jina J. Kim, Rashmi Joglekar, Jonathan D. Hibshman, Latasha L. Smith, Dhaval P. Bhatt, Olga R. Ilkayeva, Matthew D. Hirschey, Joel N. Meyer
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102000- (2021)
The consequences of damage to the mitochondrial genome (mtDNA) are poorly understood, although mtDNA is more susceptible to damage resulting from some genotoxicants than nuclear DNA (nucDNA), and many environmental toxicants target the mitochondria.
Externí odkaz:
https://doaj.org/article/b4cfc3d8ec28428e988509c328dc431a
Autor:
Kiran Busayavalasa, Mario Ruiz, Ranjan Devkota, Marcus Ståhlman, Rakesh Bodhicharla, Emma Svensk, Nils-Olov Hermansson, Jan Borén, Marc Pilon
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008975 (2020)
The C. elegans proteins PAQR-2 (a homolog of the human seven-transmembrane domain AdipoR1 and AdipoR2 proteins) and IGLR-2 (a homolog of the mammalian LRIG proteins characterized by a single transmembrane domain and the presence of immunoglobulin dom
Externí odkaz:
https://doaj.org/article/c8b6ab09e563484b9d5345fb0097c85a
Autor:
Mario Ruiz, Rakesh Bodhicharla, Marcus Ståhlman, Emma Svensk, Kiran Busayavalasa, Henrik Palmgren, Hanna Ruhanen, Jan Boren, Marc Pilon
Publikováno v:
eLife, Vol 8 (2019)
The human AdipoR1 and AdipoR2 proteins, as well as their C. elegans homolog PAQR-2, protect against cell membrane rigidification by exogenous saturated fatty acids by regulating phospholipid composition. Here, we show that mutations in the C. elegans
Externí odkaz:
https://doaj.org/article/a25d9e37660c4923ac583e6d2a9c3976
Autor:
Mario Ruiz, Rakesh Bodhicharla, Emma Svensk, Ranjan Devkota, Kiran Busayavalasa, Henrik Palmgren, Marcus Ståhlman, Jan Boren, Marc Pilon
Publikováno v:
eLife, Vol 7 (2018)
Dietary fatty acids are the main building blocks for cell membranes in animals, and mechanisms must therefore exist that compensate for dietary variations. We isolated C. elegans mutants that improved tolerance to dietary saturated fat in a sensitize
Externí odkaz:
https://doaj.org/article/375d63352e5e433c90da1bcf6f416ae5
Autor:
Ian T. Ryde, Latasha L. Smith, Olga Ilkayeva, John P. Rooney, Kathleen A. Hershberger, Jonathan D. Hibshman, Laura L. Maurer, Lauren J. Donoghue, Matthew D. Hirschey, Joel N. Meyer, Elena A. Turner, Jina J. Kim, Dhaval P. Bhatt, Rakesh Bodhicharla, Rashmi Joglekar
Publikováno v:
Redox Biology, Vol 43, Iss, Pp 102000-(2021)
Redox Biology
Redox Biology
The consequences of damage to the mitochondrial genome (mtDNA) are poorly understood, although mtDNA is more susceptible to damage resulting from some genotoxicants than nuclear DNA (nucDNA), and many environmental toxicants target the mitochondria.
Publikováno v:
Genetics. 219(1)
Communicating editor: B. Grant The composition and biophysical properties of cellular membranes must be tightly regulated to maintain the proper functions of myriad processes within cells. To better understand the importance of membrane homeostasis,
Autor:
Nils-Olov Hermansson, Jan Borén, Ranjan Devkota, Marcus Ståhlman, Kiran Busayavalasa, Emma Svensk, Mario Ruiz, Marc Pilon, Rakesh Bodhicharla
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 8, p e1008975 (2020)
PLoS Genetics, Vol 16, Iss 8, p e1008975 (2020)
The C. elegans proteins PAQR-2 (a homolog of the human seven-transmembrane domain AdipoR1 and AdipoR2 proteins) and IGLR-2 (a homolog of the mammalian LRIG proteins characterized by a single transmembrane domain and the presence of immunoglobulin dom
Autor:
Jan Borén, Mario Ruiz, Marc Pilon, Emma Svensk, Marcus Ståhlman, Hanna Ruhanen, Rakesh Bodhicharla, Henrik Palmgren, Kiran Busayavalasa
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The human AdipoR1 and AdipoR2 proteins, as well as their C. elegans homolog PAQR-2, protect against cell membrane rigidification by exogenous saturated fatty acids by regulating phospholipid composition. Here, we show that mutations in the C. elegans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580ceafa7aaa6952d1a40aee0b81cb1c
http://hdl.handle.net/10138/311283
http://hdl.handle.net/10138/311283
Publikováno v:
Genetics
The properties of cell membranes are determined mostly by the types of fatty acids that they contain. Bodhicharla et al. report that a key regulator of membrane fluidity, the PAQR-2/IGLR-2 protein complex...
Maintenance of membrane properties is
Maintenance of membrane properties is
Autor:
Hanna Ruhanen, Jan Borén, Kiran Busayavalasa, Marcus Ståhlman, Emma Svensk, Henrik Palmgren, Marc Pilon, Mario Ruiz, Rakesh Bodhicharla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd28071ed687f63486e53fb9da032630
https://doi.org/10.7554/elife.47733.sa2
https://doi.org/10.7554/elife.47733.sa2