Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Rakesh, Sindhi"'
Autor:
Chethan Ashokkumar, PhD, Mylarappa Ningappa, PhD, Vikram Raghu, MD, George Mazariegos, MD, Brandon W. Higgs, PhD, Paul Morgan, BS, Lisa Remaley, PAC, Tamara Fazzolare Martin, PAC, Pamela Holzer, BSN, Kevin Trostle, MBA, Qingyong Xu, PhD, Adriana Zeevi, PhD, James Squires, MD, Kyle Soltys, MD, Simon Horslen, MBChB, Ajai Khanna, MD, Armando Ganoza, MD, Rakesh Sindhi, MD, FACS
Publikováno v:
Transplantation Direct, Vol 10, Iss 3, p e1589 (2024)
Background. Enhanced B-cell presentation of donor alloantigen relative to presentation of HLA-mismatched reference alloantigen is associated with acute cellular rejection (ACR), when expressed as a ratio called the antigen presenting index (API) in a
Externí odkaz:
https://doaj.org/article/2cb091ac54a0485cb681d6a2f843db9e
Autor:
Mylarappa Ningappa, PhD, Xiaojian Shao, PhD, Chethan Ashokkumar, PhD, Qingyong Xu, PhD, Adriana Zeevi, PhD, Elin Grundberg, PhD, Tomi Pastinen, MD, PhD, Rakesh Sindhi, MD
Publikováno v:
Transplantation Direct, Vol 8, Iss 11, p e1394 (2022)
Background. Transcriptional regulation of liver transplant (LT) rejection may reveal novel predictive and therapeutic targets. The purpose of this article is to test the role of differential DNA methylation in children with biopsy-proven acute cellul
Externí odkaz:
https://doaj.org/article/0e66d86e61314cff85f7194906a7eacf
Autor:
Vikram K. Raghu, Steven F. Dobrowolski, Rakesh Sindhi, Kevin A. Strauss, George V. Mazariegos, Jerry Vockley, Kyle Soltys
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 31, Iss , Pp 100866- (2022)
Classical phenylketonuria (PKU) presents a unique challenge for women of child-bearing age. In the context of pregnancy, poorly controlled hyperphenylalaninemia can result in a devastating constellation of outcomes for the baby referred to as the mat
Externí odkaz:
https://doaj.org/article/2bf363ef50404c388650e2ff2becc09c
Autor:
Kavitha Mukund, Priya Nayak, Chethan Ashokkumar, Sohail Rao, Jose Almeda, Monica M. Betancourt-Garcia, Rakesh Sindhi, Shankar Subramaniam
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The mechanisms underlying the immune remodeling and severity response in coronavirus disease 2019 (COVID-19) are yet to be fully elucidated. Our comprehensive integrative analyses of single-cell RNA sequencing (scRNAseq) data from four published stud
Externí odkaz:
https://doaj.org/article/b36a09dd29324e589624ca9ede364ae4
Autor:
Mylarappa Ningappa, Morayooluwa Adenuga, Kim A. Ngo, Nada Mohamed, Tejaswini Narayanan, Krishna Prasadan, Chethan Ashokkumar, Jishnu Das, Lori Schmitt, Hannah Hartman, Anuradha Sehrawat, Claudia M. Salgado, Miguel Reyes-Mugica, George K. Gittes, Cecilia W. Lo, Shankar Subramaniam, Rakesh Sindhi
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundCiliary defects cause heterogenous phenotypes related to mutation burden which lead to impaired development. A previously reported homozygous deletion in the Man1a2 gene causes lethal respiratory failure in newborn pups and decreased lung c
Externí odkaz:
https://doaj.org/article/3f4d7397ddc74908a9f0fca602f5c229
Autor:
Neslihan Celik, James E. Squires, Kyle Soltys, Jerry Vockley, Diana A. Shellmer, Wonbae Chang, Kevin Strauss, Patrick McKiernan, Armando Ganoza, Rakesh Sindhi, Geoffrey Bond, George Mazariegos, Ajai Khanna
Publikováno v:
JIMD Reports, Vol 48, Iss 1, Pp 83-89 (2019)
Abstract Domino liver transplantation (DLT) involves transplanting liver from a patient with metabolic disease into a patient with end‐stage liver disease with the expectation that the recipient will not develop the metabolic syndrome or the recurr
Externí odkaz:
https://doaj.org/article/ea821d9940a8484ea29ba02a420e5197
Autor:
Juhoon So, Mylarappa Ningappa, Joseph Glessner, Jun Min, Chethan Ashokkumar, Sarangarajan Ranganathan, Brandon W. Higgs, Dong Li, Qing Sun, Lori Schmitt, Amy C. Biery, Steven Dobrowolski, Christine Trautz, Leah Fuhrman, Molly Christine Schwartz, Nikolai Thomas Klena, Joseph Fusco, Krishna Prasadan, Morayooluwa Adenuga, Nada Mohamed, Qi Yan, Wei Chen, William Horne, Anil Dhawan, Khalid Sharif, Deirdre Kelly, Robert H Squires, George K. Gittes, Hakon Hakonarson, Victor Morell, Cecilia Lo, Shankar Subramaniam, Donghun Shin, Rakesh Sindhi
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Background/AimsInfectious and genetic factors are invoked, respectively in isolated biliary atresia (BA), or syndromic BA, with major extrahepatic anomalies. However, isolated BA is also associated with minor extrahepatic gut and cardiovascular anoma
Externí odkaz:
https://doaj.org/article/e1c329030930403a8e3a5542aa7c32a8
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Biliary atresia (BA), blockage of the proper bile flow due to loss of extrahepatic bile ducts, is a rare, complex disease of the liver and the bile ducts with unknown etiology. Despite ongoing investigations to understand its complex pathogenesis, BA
Externí odkaz:
https://doaj.org/article/fe675884cb9d43cfbada8192a8be2f21
Autor:
Lisa Remaley, Chethan Ashokkumar, Kyle A. Soltys, George Vincent Mazariegos, Geoffrey James Bond, Ajai Khanna, Armando Ganoza, Miguel Reyes‐Mugica, Adriana Zeevi, Rakesh Sindhi
Publikováno v:
Pediatric Transplantation. 27
Publikováno v:
Pediatric Transplantation. 27