Ethno-geographic distribution and histopathological classification of nasopharyngeal carcinoma in a single center in Nepal.

Autor: Subhas Pandit, Simit Sapkota, Abish Adhikari, Prakriti Karki, Deepak Yadav, Roshani Shrestha, Rijendra Yogal, Sanat Chalise, Rakesh Pathak, Anjani Kumar Jha

Publikováno v: PLoS ONE, Vol 19, Iss 5, p e0304371 (2024)

IntroductionNasopharyngeal carcinoma (NPC) shows geographic and ethnic variation with specific etiopathogenesis. This study characterized the distribution of NPC patients stratified by ethnicity, geography, and histology in a tertiary-level cancer ce

Externí odkaz: https://doaj.org/article/4a4f39781ba54f15a3d6a1b95d060a13

Adult stem cell deficits drive Slc29a3 disorders in mice

Autor: Sreenath Nair, Anne M. Strohecker, Avinash K. Persaud, Bhawana Bissa, Shanmugam Muruganandan, Craig McElroy, Rakesh Pathak, Michelle Williams, Radhika Raj, Amal Kaddoumi, Alex Sparreboom, Aaron M. Beedle, Rajgopal Govindarajan

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)

Mutations in equilibrative nucleoside transporter 3 (ENT3), encoded by SLC29A3, cause a spectrum of human genetic disorders. Here, the authors show altered haematopoietic stem cell and mesenchymal stem cell fates in ENT3-deficient mice, due to misreg

Externí odkaz: https://doaj.org/article/808693518ee945b095baa8826e112354

Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation

Autor: Si Young Lee, Stevephen Hung, Caroline Esnault, Rakesh Pathak, Kory R. Johnson, Oluwadamilola Bankole, Akira Yamashita, Hongen Zhang, Henry L. Levin

Publikováno v: Cell Reports, Vol 30, Iss 8, Pp 2686-2698.e8 (2020)

Summary: Heterochromatin functions as a scaffold for factors responsible for gene silencing and chromosome segregation. Heterochromatin can be assembled by multiple pathways, including RNAi and RNA surveillance. We identified factors that form hetero

Externí odkaz: https://doaj.org/article/74e98dc7dde943b3b38d3262c02bac87

Primary Melanoma of Testis- A Case Report

Autor: Sujata Pudasaini, Bhola Raj Joshi, Neeraj Subedi, Rakesh Pathak, Kricha Pande, Shradha Koirala, Neeta Kafle, Krishna Kaji Bhomi, Aanchal Shahi

Publikováno v: Nepalese Medical Journal, Vol 1, Iss 2, Pp 121-123 (2018)

Primary melanoma of the testis is very rare. Melanoma of testis usually occurs as metastatic tumor. Here we present a case of 54 year old man with right testicular swelling proven to be primary malignant melanoma. Patient had right scrotal swelling o

Externí odkaz: https://doaj.org/article/dd9b5e65c45a4afc94235999b01fcc3f

Genetic Markers and Biotechnology

Autor: Rakesh Pathak

Publikováno v: Genetics, Physiology and Cultivation of Moth Bean, Cowpea and Horse Gram ISBN: 9789811999550
Clusterbean: Physiology, Genetics and Cultivation ISBN: 9789812879059

Clusterbean is an obligatory self-pollinating and inbreeding species and therefore, little variation in DNA polymorphism is expected among the cultivars. It has triploid endosperm and has more vegetative growth as compared to diploid counterparts. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad594be38d8a39f93d479c323a351090
https://doi.org/10.1007/978-981-19-9956-7_7