Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rakesh, Manandhar"'
Autor:
Yasmin Husaini, Vicky Wang-Wei Tsai, Rakesh Manandhar, Hong Ping Zhang, Ka Ki Michelle Lee-Ng, Hélène Lebhar, Christopher P Marquis, David A Brown, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233846 (2020)
Growth Differentiation Factor-15 (GDF15) is a divergent TGF-beta superfamily cytokine that is overexpressed by most cancers and is induced by anticancer therapy. Transgenic and induced animal models suggest that it protects from cancer development bu
Externí odkaz:
https://doaj.org/article/c03491e8a640495c96e487c633b150be
Autor:
Vicky Wang-Wei Tsai, Laurence Macia, Christine Feinle-Bisset, Rakesh Manandhar, Arne Astrup, Anne Raben, Janne Kunchel Lorenzen, Peter T Schmidt, Fredrik Wiklund, Nancy L Pedersen, Lesley Campbell, Adamandia Kriketos, Aimin Xu, Zhou Pengcheng, Weiping Jia, Paul M G Curmi, Christopher N Angstmann, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Christopher P Marquis, Yasmin Husaini, Christoph Beglinger, Shu Lin, Herbert Herzog, David A Brown, Amanda Sainsbury, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133362 (2015)
The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct
Externí odkaz:
https://doaj.org/article/737ad1ed5f8142afac832eb05e943fb9
Autor:
Vicky Wang-Wei Tsai, Rakesh Manandhar, Sebastian Beck Jørgensen, Ka Ki Michelle Lee-Ng, Hong Ping Zhang, Christopher Peter Marquis, Lele Jiang, Yasmin Husaini, Shu Lin, Amanda Sainsbury, Paul E Sawchenko, David A Brown, Samuel N Breit
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100370 (2014)
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) modulates food intake and body weight under physiological and pathological conditions by acting on the hypothalamus and brainstem. When overexpressed in disease, such as in advanced cancer, elevated seru
Externí odkaz:
https://doaj.org/article/5e99da808d224bdbb2047faf1def0d0f
Autor:
Helene Lebhar, Hong Ping Zhang, Samuel N. Breit, Vicky Wang-Wei Tsai, Amanda Sainsbury, David Brown, Christopher P. Marquis, Ka Ki Michelle Lee-Ng, Rakesh Manandhar, Yasmin Husaini
Publikováno v:
International Journal of Obesity. 42:561-571
To test the potential efficacy of recombinant macrophage inhibitory cytokine-1 (MIC-1/GDF15) as an obesity therapeutic. Male C57BL/6 J mice, either fed on normal chow or high-fat diet for 16 weeks to induce diet-induced obesity, were infused with eit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4da2c032ae100b1b87cccad9d6297a1
https://doi.org/10.1038/ijo.2017.258
https://doi.org/10.1038/ijo.2017.258
Autor:
Hong Ping Zhang, Rakesh Manandhar, Helene Lebhar, Ka Ki Michelle Lee-Ng, Vicky Wang-Wei Tsai, Samuel N. Breit, Christopher P. Marquis, Yasmin Husaini, David Brown
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0233846 (2020)
PLoS ONE, Vol 15, Iss 6, p e0233846 (2020)
Growth Differentiation Factor-15 (GDF15) is a divergent TGF-beta superfamily cytokine that is overexpressed by most cancers and is induced by anticancer therapy. Transgenic and induced animal models suggest that it protects from cancer development bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952d15a875dabcd218cb2dacd38ebd74
https://pubmed.ncbi.nlm.nih.gov/32502202
https://pubmed.ncbi.nlm.nih.gov/32502202
Autor:
Vicky Wang-Wei, Tsai, Hong Ping, Zhang, Rakesh, Manandhar, Peter, Schofield, Daniel, Christ, Ka Ki Michelle, Lee-Ng, Hélène, Lebhar, Christopher Peter, Marquis, Yasmin, Husaini, David A, Brown, Samuel N, Breit
Publikováno v:
International journal of obesity (2005). 43(12)
Elevated circulating levels of the divergent transforming growth factor-beta (TGFb) family cytokine, growth differentiation factor 15 (GDF15), acting through its CNS receptor, glial-derived neurotrophic factor receptor alpha-like (GFRAL), can cause a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dec98c0a1cc895296fb6dddadee3850
https://pubmed.ncbi.nlm.nih.gov/31152154
https://pubmed.ncbi.nlm.nih.gov/31152154
Autor:
Ka Ki Michelle Lee-Ng, Lele Jiang, Hong Ping Zhang, Rakesh Manandhar, David Brown, Shu Lin, Vicky Wang-Wei Tsai, Amanda Sainsbury, Christopher P. Marquis, Sebastian Beck Jørgensen, Paul E. Sawchenko, Samuel N. Breit, Yasmin Husaini
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e100370 (2014)
PLoS ONE, Vol 9, Iss 6, p e100370 (2014)
Macrophage inhibitory cytokine-1 (MIC-1/GDF15) modulates food intake and body weight under physiological and pathological conditions by acting on the hypothalamus and brainstem. When overexpressed in disease, such as in advanced cancer, elevated seru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e4c5777eaab1ec27e3935b61510929
https://hdl.handle.net/2123/16092
https://hdl.handle.net/2123/16092
Autor:
Shu Lin, Kate Harriott, Rakesh Manandhar, Hong Ping Zhang, Samuel N. Breit, K. K. Michelle Lee-Ng, Lele Jiang, Yasmin Husaini, Vicky Wang-Wei Tsai, Amanda Sainsbury, David Brown
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Anorexia/cachexia is a common and currently mostly untreatable complication of advanced cancer. It is also a feature of a number of chronic diseases and can also occur as part of the normal ageing process. Over recent years, two different, but someti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a907a84cb8730f7df500a3e9c9c457e6
https://hdl.handle.net/2123/16093
https://hdl.handle.net/2123/16093
Autor:
RA Hawksworth, C. Ruth Butlin, Rakesh Manandhar, Jason Worley, Mahesh Shah, Joe LeMaster, Niraj Shrestha, Paul W Roche, Gilla Kaplan, A. Steven Lubinsky, Matthew L. Albert, Patrick A. J. Haslett, Murdo Macdonald
Publikováno v:
The Journal of infectious diseases. 192(12)
The immunomodulatory drug thalidomide is the treatment of choice for erythema nodosum leprosum (ENL), an inflammatory cutaneous and systemic complication of multibacillary leprosy. To elucidate the mechanism of action of thalidomide in this syndrome,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5911f857c488fe42ca5b2f3409eb4951
https://pubmed.ncbi.nlm.nih.gov/16703522
https://pubmed.ncbi.nlm.nih.gov/16703522
Autor:
Henrik Grönberg, Vicky Wang-Wei Tsai, Amanda Sainsbury, Laurence Macia, Rakesh Manandhar, Nancy L. Pedersen, Herbert Herzog, Hong Ping Zhang, Michel Lee-Ng, Fredrik Wiklund, Samuel N. Breit, David Brown
Publikováno v:
Obesity Research & Clinical Practice. 8:105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d9302a8d29de0eef55bcb92be267a8
https://doi.org/10.1016/j.orcp.2014.10.191
https://doi.org/10.1016/j.orcp.2014.10.191