Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rakeeb Kureshi"'
Autor:
Michael J. Walsh, Courtney T. Stump, Rakeeb Kureshi, Patrick Lenehan, Lestat R. Ali, Michael Dougan, David M. Knipe, Stephanie K. Dougan
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112219- (2023)
Summary: Tumors in immune equilibrium are held in balance between outgrowth and destruction by the immune system. The equilibrium phase defines the duration of clinical remission and stable disease, and escape from equilibrium remains a major clinica
Externí odkaz:
https://doaj.org/article/f1f8592f2d8e4bfab43410d828e98a6f
Autor:
Jordan J. Green, Stephany Y. Tzeng, Rakeeb Kureshi, Leilani R. Astrab, Jikui Shen, Paul R. Sargunas, Peter A. Campochiaro, Angela Zhu, Jamie B. Spangler
Publikováno v:
Cell Mol Bioeng
BACKGROUND: Ocular neovascularization is a hallmark of retinal diseases including neovascular age-related macular degeneration and diabetic retinopathy, two leading causes of blindness in adults. Neovascularization is driven by the interaction of sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf73239c475e038535c2f3e6f62711e
https://doi.org/10.1007/s12195-020-00641-0
https://doi.org/10.1007/s12195-020-00641-0
Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics
Autor:
Ronnie C. Mease, Michele Doucet, Sridhar Nimmagadda, Edward Gabrielson, Ala Lisok, Sagar Shelake, Sudipto Ganguly, Akhilesh Mishra, Elizabeth M. Jaffee, Rupashree Sen, Patrick M. Forde, Dhananjay Vaidya, Ravindra A. De Silva, Jamie B. Spangler, Donika Plyku, Dhiraj Kumar, Rakeeb Kureshi, Prashant Desai
Publikováno v:
Proc Natl Acad Sci U S A
Macromolecules such as monoclonal antibodies (mAbs) are likely to experience poor tumor penetration because of their large size, and thus low drug exposure of target cells within a tumor could contribute to suboptimal responses. Given the challenge o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ced9dada89c717a212c0d9ef6d1cf58
https://doi.org/10.1073/pnas.2107982118
https://doi.org/10.1073/pnas.2107982118
Publikováno v:
Current Opinion in Chemical Engineering. 19:27-34
Fundamental advances in the field of biomolecular engineering present researchers with the unprecedented opportunity to apply molecular design strategies to modify naturally occurring proteins and generate new molecules for targeted disease therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a57368a753258c18b78f600854034f
https://doi.org/10.1016/j.coche.2017.12.003
https://doi.org/10.1016/j.coche.2017.12.003
Publikováno v:
Advances in experimental medicine and biology. 1172
The common γ chain (γ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c4352ef4f411f36535e1311b4ec68d4
https://pubmed.ncbi.nlm.nih.gov/31628649
https://pubmed.ncbi.nlm.nih.gov/31628649
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811393662
The common γ chain (γc) family of hematopoietic cytokines consists of six distinct four α-helix bundle soluble ligands that signal through receptors which include the shared γc subunit to coordinate a wide range of physiological processes, in par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4242a0d0c7182c27ff1bdf6a7796191f
https://doi.org/10.1007/978-981-13-9367-9_1
https://doi.org/10.1007/978-981-13-9367-9_1
