Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Raju R. Rayavarapu"'
Autor:
Zhenya Hong, Jane E. Craig, Taosheng Chen, Lily Jun Shen Huang, Wei Zhuang, Gamze B. Bulut, Sadie Miki Sakurada, Jonathan Low, Malia B. Potts, Jamshid Temirov, Joseph N. Miller, Raju R. Rayavarapu, Shondra M. Pruett-Miller
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Mitochondria are vital organelles that coordinate cellular energy homeostasis and have important roles in cell death. Therefore, the removal of damaged or excessive mitochondria is critical for maintaining proper cellular function. The PINK1-Parkin p
Autor:
Nicholas Pagani, Sydney Shuff, Siyuan Zhang, Brendan Heiden, Raju R. Rayavarapu, Melissa M. Shaw, Zachary T. Schafer
Publikováno v:
Journal of Biological Chemistry. 290:8722-8733
The metastasis of cancer cells from the site of the primary tumor to distant sites in the body represents the most deadly manifestation of cancer. In order for metastasis to occur, cancer cells need to evade anoikis, which is defined as apoptosis cau
Autor:
Raju R. Rayavarapu, Nicholas Pagani, Brendan Heiden, Chelsea McCallister, Melissa M. Shaw, Zachary T. Schafer, Sydeny Shuff
Publikováno v:
Cancer Research. 76:3563-3563
Hyperactivating mutations in Ras are found in a significant percentage of cancers, with a particularly high frequency in pancreatic and colon carcinomas. The hyperactivation of Ras drives a vast number of distinct downstream signaling pathways that p
Publikováno v:
Seminars in celldevelopmental biology. 23(4)
The metastasis of cancer cells to distant sites is responsible for the vast majority of cancer mortalities yet the molecular mechanisms underlying this extraordinarily complicated process have yet to be sufficiently elucidated. Recently, it has becom
Publikováno v:
Cancer Research. 74:1347-1347
Normal epithelial cells require attachment to the extracellular matrix (ECM) in order to survive. When detached from the ECM, normal cells will undergo apoptosis through a process known as anoikis. The ErbB2 receptor tyrosine kinase is well known to
Autor:
Zachary T. Schafer, Raju R. Rayavarapu
Publikováno v:
Cancer Research. 72:2082-2082
Normal epithelial cells require attachment to the extracellular matrix (ECM) in order to proliferate and survive. Binding to the ECM facilitates the activation of pathways responsible for ATP production and cell survival. When detached from the ECM,