Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Raju Mannoori"'
Autor:
Barri Wautlet, Lalgudi S. Harikrishnan, Jonathan Lippy, Andrew J. Tebben, Amol G. Dikundwar, P.N. Arunachalam, Raju Mannoori, Max Ruzanov, Yi Fan, Gopikishan Tonukunuru, Vishweshwaraiah Baligar, Mark Fereshteh, Balaji Seshadri, Jayakumar Warrier, Sudhakara R. Madduri, Joseph Fargnoli, Robert M. Borzilleri, Ching-Ping Ho, Brian E. Fink, Steven Sheriff, Hasibur Rahaman
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:1026-1034
The TGFβ-TGFβR signaling pathway has been reported to play a protective role in the later stages of tumorigenesis via increasing immunosuppressive Treg cells and facilitating the epithelial to mesenchymal transition (EMT). Therefore, inhibition of
Autor:
Arvind Mathur, Rajareddy Kallem, Thaddeus F. Molski, Manjunatha Narayana Rao Kamble, Michelle Nophsker, Huiping Zhang, Murali Subramanian, Dalton King, Linda J. Bristow, Lawrence R. Marcin, B.N. Srikumar, Grandhi Venkat Ram Krishna Mohan Gupta, Kumar Kuchibhotla Vijaya, Jayakumar Sankara Warrier, Michael Sinz, Charulatha Sanmathi, G. Nagaraju, Xiaoliang Zhuo, Raju Mannoori, Imadul Islam, Alicia Ng, Pattipati S. Naidu, Eric Shields, Joanne J. Bronson, Narasimharaju Kalidindi, Reeba K. Vikramadithyan, Gopikishan Tonukunuru, Lorin A. Thompson, James Kempson, Srinivasan Thangathirupathy, Jogi Srinivas, Bradley C. Pearce, Jyoti Gulia, Jean Simmermacher, Srinivas Cheruku, Mahesh Paschapur, Jianliang Shi, John E. Macor, Jayant Aher, Manjunath Ramarao, Charlie F. Albright, Richard E. Olson, Rex Denton, Aliphedi B. Reddy, Hyunsoo Park, Karageorge George N, Tanmaya Bastia, Jianqing Li
Publikováno v:
ACS medicinal chemistry letters. 9(5)
[Image: see text] There is a significant unmet medical need for more efficacious and rapidly acting antidepressants. Toward this end, negative allosteric modulators of the N-methyl-d-aspartate receptor subtype GluN2B have demonstrated encouraging the