Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Raju K, Pillai"'
Autor:
Yiming Wu, Meiling Jin, Mike Fernandez, Kevyn L. Hart, Aijun Liao, Xinzhou Ge, Stacey M. Fernandes, Tinisha McDonald, Zhenhua Chen, Daniel Röth, Lucy Y. Ghoda, Guido Marcucci, Markus Kalkum, Raju K. Pillai, Alexey V. Danilov, Jingyi Jessica Li, Jianjun Chen, Jennifer R. Brown, Steven T. Rosen, Tanya Siddiqi, Lili Wang
Publikováno v:
Blood Cancer Discovery. 4:228-245
RNA splicing dysregulation underlies the onset and progression of cancers. In chronic lymphocytic leukemia (CLL), spliceosome mutations leading to aberrant splicing occur in ∼20% of patients. However, the mechanism for splicing defects in spliceoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f59e66bbcb53acb6868dcbd18b6c01
https://doi.org/10.1158/2643-3230.bcd-22-0156
https://doi.org/10.1158/2643-3230.bcd-22-0156
Autor:
Karen L Reckamp, Jasmine A McQuerry, Isa Mambetsariev, Rebecca Pharaon, Susan E Yost, Jeremy Fricke, Tamara Mirzapoiazova, Raju K Pillai, Leonidas Arvanitis, Ziad Khan, Marwan Fakih, Yuan Yuan, Marianna Koczywas, Erminia Massarelli, Prakash Kulkarni, Sumanta K Pal, Martin Sattler, Andrea Bild, Ravi Salgia
Publikováno v:
Future Science OA, Vol 7, Iss 2 (2021)
The implication of MET alterations in solid tumors and the immune microenvironment remains elusive. Formalin-fixed, paraffin-embedded samples of 21 patients with solid tumors harboring MET alterations were used for immunohistochemical staining. Extra
Externí odkaz:
https://doaj.org/article/db9101794002492f80999b72d5baf66a
Publikováno v:
Cells, Vol 10, Iss 10, p 2698 (2021)
In vitro modeling of hematological malignancies not only provides insights into the influence of genetic aberrations on cellular and molecular mechanisms involved in disease progression but also aids development and evaluation of therapeutic agents.
Externí odkaz:
https://doaj.org/article/68059fe3fd6540b0a3a0bb6bee662a83
Autor:
Jibin Zhang, Tingting Wang, Kunal Shetty, Serhan Alkan, Senlin Xu, Qiang Gong, Xuxiang Liu, Yuping Li, Zunsong Hu, Wendong Huang, Hans-Guido Wendel, Alex F. Herrera, Raju K. Pillai, Joo Y. Song, Wing C. Chan
Publikováno v:
Blood Advances. 6:5067-5071
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd319164b509e762fc8994f166af2e82
https://doi.org/10.1182/bloodadvances.2021006709
https://doi.org/10.1182/bloodadvances.2021006709
Autor:
Lili Wang, Tanya Siddiqi, Steven T. Rosen, Jennifer R. Brown, Jianjun Chen, Jingyi Jessica Li, Alexey V. Danilov, Raju K. Pillai, Markus Kalkum, Guido Marcucci, Lucy Y. Ghoda, Daniel Röth, Zhenhua Chen, Tinisha McDonald, Stacey M. Fernandes, Xinzhou Ge, Aijun Liao, Kevyn L. Hart, Mike Fernandez, Meiling Jin, Yiming Wu
Fig S1. SF3B1 mutant CLL samples had pervasive changes in 3’ splice site. Fig S2. Omics analyses identify widespread post-transcriptional upregulation of splicing factors in CLL. Fig S3. Abundance of spliceosome complexes and RNA-binding proteins a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731b0511ef858cdcd0980d89ebbc9c1a
https://doi.org/10.1158/2643-3230.22645217
https://doi.org/10.1158/2643-3230.22645217
Autor:
Lili Wang, Tanya Siddiqi, Steven T. Rosen, Jennifer R. Brown, Jianjun Chen, Jingyi Jessica Li, Alexey V. Danilov, Raju K. Pillai, Markus Kalkum, Guido Marcucci, Lucy Y. Ghoda, Daniel Röth, Zhenhua Chen, Tinisha McDonald, Stacey M. Fernandes, Xinzhou Ge, Aijun Liao, Kevyn L. Hart, Mike Fernandez, Meiling Jin, Yiming Wu
RNA splicing dysregulation underlies the onset and progression of cancers. In chronic lymphocytic leukemia (CLL), spliceosome mutations leading to aberrant splicing occur in ∼20% of patients. However, the mechanism for splicing defects in spliceoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a5d650883778aa792bb8a1f69dd477
https://doi.org/10.1158/2643-3230.c.6603185.v1
https://doi.org/10.1158/2643-3230.c.6603185.v1
Autor:
Lili Wang, Tanya Siddiqi, Steven T. Rosen, Jennifer R. Brown, Jianjun Chen, Jingyi Jessica Li, Alexey V. Danilov, Raju K. Pillai, Markus Kalkum, Guido Marcucci, Lucy Y. Ghoda, Daniel Röth, Zhenhua Chen, Tinisha McDonald, Stacey M. Fernandes, Xinzhou Ge, Aijun Liao, Kevyn L. Hart, Mike Fernandez, Meiling Jin, Yiming Wu
Table S1 shows CLL sample information; Table S2 shows protein expression detected in CLL and normal B cells using TMT proteomics; Table S3 shows top 150 transcripts with highest m6A density in B cells; Table S4 shows sequences of shRNAs, sgRNAs, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b3c15566f7d9d7e875e52b3e8dee19
https://doi.org/10.1158/2643-3230.22645214
https://doi.org/10.1158/2643-3230.22645214
Autor:
Yuan Yuan, Ferdynand J. Kos, Ting-Fang He, Hongwei H. Yin, Mengsha Li, Nicola Hardwick, Kathryn Zurcher, Daniel Schmolze, Peter Lee, Raju K. Pillai, Vincent Chung, Don J. Diamond
Publikováno v:
OncoImmunology, Vol 6, Iss 12 (2017)
A heavily pretreated patient with triple negative breast cancer distinguished by cutaneous metastases received p53MVA vaccine in combination with pembrolizumab. Her cutaneous metastases regressed and after 2 cycles of therapy, a skin biopsy showed a
Externí odkaz:
https://doaj.org/article/8de6fa1660a846e287d8dbff26db8687
Autor:
Yiming Wu, Meiling Jin, Mike Fernandez, Kevyn Hart, Aijun Liao, Stacey M. Fernandes, Tinisha McDonald, Zhenhua Chen, Daniel Röth, Lucy Ghoda, Guido Marcucci, Markus Kalkum, Raju K. Pillai, Alexey V. Danilov, Jianjun Chen, Jennifer R. Brown, Steven T. Rosen, Tanya Siddiqi, Lili Wang
Publikováno v:
Cancer Research. 83:3482-3482
RNA splicing dysregulation is a hallmark of cancers and underlies the onset and progression of diseases. Chronic lymphocytic leukemia (CLL) is one of the most common adult leukemia in western countries. Spliceosome mutations occur in ~20% of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c40cf3b5fa85a3317ea3817d2b2d266
https://doi.org/10.1158/1538-7445.am2023-3482
https://doi.org/10.1158/1538-7445.am2023-3482
Autor:
Raju K, Pillai, Michelle, Afkhami
Publikováno v:
Cancer treatment and research. 181
Advances in high-throughput DNA sequencing technology in the past decade have made a tremendous impact on basic science and clinical practice. Methods using the latest next generation sequencing technology can sequence an entire human genome within a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb2f8dfaa1fb822b4682485498d0f4a4
https://pubmed.ncbi.nlm.nih.gov/34626352
https://pubmed.ncbi.nlm.nih.gov/34626352