Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Raju C. Reddy"'
Publikováno v:
PPAR Research, Vol 2017 (2017)
Lung cancer is the most common and most fatal of all malignancies worldwide. Furthermore, with more than half of all lung cancer patients presenting with distant metastases at the time of initial diagnosis, the overall prognosis for the disease is po
Externí odkaz:
https://doaj.org/article/56bbb084cd314d1f803bed0b8cf46a1a
Publikováno v:
PPAR Research, Vol 2016 (2016)
Peroxisome proliferator-activated receptor γ (PPARγ) is now recognized as an important modulator of leukocyte inflammatory responses and function. Its immunoregulatory function has been studied in a variety of contexts, including bacterial infectio
Externí odkaz:
https://doaj.org/article/4892c5c4cfd54cf8bdda7ab7f66acfb7
Publikováno v:
PPAR Research, Vol 2016 (2016)
Lung cancer is the leading cause of cancer-related death, with more than half the patients having advanced-stage disease at the time of initial diagnosis and thus facing a poor prognosis. This dire situation poses a need for new approaches in prevent
Externí odkaz:
https://doaj.org/article/067305f800cd400e9ce3b4c40f31cb37
Autor:
Raju C. Reddy, Anjaiah Srirangam, Kaunteya Reddy, Jun Chen, Srinivasareddy Gangireddy, Gregory P. Kalemkerian, Theodore J. Standiford, Venkateshwar G. Keshamouni
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 6, Pp 597-603 (2008)
Preclinical studies have shown that peroxisome proliferator–activated receptor γ (PPAR-γ) ligands can exert antitumor effects against non–small cell lung cancer (NSCLC) and a variety of other cancers. In this study, we investigate the potential
Externí odkaz:
https://doaj.org/article/a876a23d589143ad8ff3896ab75ec190
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 8, Pp 1874-1880 (2006)
In this study, we report novel and simple chemical syntheses of acyl dihydroxyacetone phosphate (DHAP) and 1-acyl glycero-3-phosphate [lysophosphatidic acid (LPA)], key intermediaries in the formation of glycerolipids containing ester and ether bonds
Externí odkaz:
https://doaj.org/article/578fe560a07e4b86a1f79f355a9d7e95
Autor:
Venkateshwar G. Keshamouni, Douglas A. Arenberg, Raju C. Reddy, Michael J. Newstead, Shalini Anthwal, Theodore J. Standiford
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 3, Pp 294-301 (2005)
Activation of peroxisome proliferator-activated receptor-γ (PPAR-γ) results in inhibition of tumor growth in various types of cancers, but the mechanism(s) by which PPAR-γ induces growth arrest has not been completely defined. In a recent study, w
Externí odkaz:
https://doaj.org/article/26caae721ac14aec8cef75e5ca69de98
The Nitrated Fatty Acid 10-Nitro-oleate Diminishes Severity of LPS-Induced Acute Lung Injury in Mice
Publikováno v:
PPAR Research, Vol 2012 (2012)
Acute lung injury (ALI) is an inflammatory condition culminating in respiratory failure. There is currently no effective pharmacological treatment. Nitrated fatty acids (NFAs) have been shown to exert anti-inflammatory effects. We therefore hypothesi
Externí odkaz:
https://doaj.org/article/1e10a4540df74a1d8118c0b6e5520881
Publikováno v:
PPAR Research, Vol 2012 (2012)
Externí odkaz:
https://doaj.org/article/922af18b62484a9bb9cef8e911093d2a
Publikováno v:
PPAR Research, Vol 2007 (2007)
PPARs, most notably PPAR-γ, play a crucial role in regulating the activation of alveolar macrophages, which in turn occupy a pivotal place in the immune response to pathogens and particulates drawn in with inspired air. In this review, we describe t
Externí odkaz:
https://doaj.org/article/c644afc20a074ecaa0e225f0bb5c3177
Publikováno v:
Clinical Science. 134:1063-1079
Asthma is a chronic disease of the airways that has long been viewed predominately as an inflammatory condition. Accordingly, current therapeutic interventions focus primarily on resolving inflammation. However, the mainstay of asthma therapy neither
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21da514122435d92bc55ccc201be5ae
https://doi.org/10.1042/cs20191309
https://doi.org/10.1042/cs20191309