Výsledky vyhledávání - "Raju, Chedupaka"

One-pot, three-component synthesis, anti-bacterial and molecular modelling studies of novel benzimidazole based isoindoline-1,3-dione and benzo[4,5]imidazo[2,1-b]thiazol hybrids

Autor: Raju Chedupaka, Shyam Perugu, Srikanth Mamidala, Venkatesham Papisetti, Santhosh Penta, Rajeswar Rao Vedula

A series of metal-free, thioalkylated benzimidazole-based isoindoline-1,3-dione (4a-w) and N-fused 4,5-benzo[4,5]imidaz[2,1-b]thiazole (5a-h) derivatives were synthesized via a novel, one-pot three-component approach. All the synthesized scaffolds we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d241cef5f6824276ca5b4bef832fc2f3
https://doi.org/10.21203/rs.3.rs-2876198/v1

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Facile, One-pot, pseudo four component synthesis of novel benzimidazolyl- thiazoles via multi-component approach and their biological evaluation

Autor: Raju Chedupaka, Amrutha V Audipudi, Akansha Ashok Sangolkar, Srikanth Mamidala, Papisetti Venkatesham, Santhosh Penta, Rajeswar Rao Vedula

A general and sustainable multicomponent approach for the synthesis of benzimidazolyl-thiazole compounds via an efficient, one-pot, pseudo four-component reaction using 5-amino-2-mercaptobenzimidazole, aralkyl halides, ammonium thiocyanate, and subst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::378f92424810805d1bf996480ea9388b
https://doi.org/10.21203/rs.3.rs-2606193/v1

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New class of fused [3,2-b][1,2,4]triazolothiazoles for targeting glioma in vitro

Autor: Papisetti Venkatesham, Nikhil Ranjan, Anwita Mudiraj, Vinutha Kuchana, Raju Chedupaka, Vijjulatha Manga, Phanithi Prakash Babu, Rajeswar Rao Vedula

Publikováno v: Bioorganicmedicinal chemistry letters. 80

Glioma is aggressive malignant tumor with limited therapeutic interventions. Herein we report the synthesis of fused bicyclic 1,2,4-triazolothiazoles by a one-pot multi-component approach and their activity against C6 rat and LN18 human glioma cell l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115ef4787f255eab0d5b2b54af806862
https://pubmed.ncbi.nlm.nih.gov/36494051

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Synthesis, characterization and Density Functional Theory of novel one-pot thioalkylated benzimidazole-linked 4-substituted mercaptoimidazole molecular hybrids via multi-component approach

Autor: Raju Chedupaka, Ravinder Pawar, Papisetti Venkatesham, Rajeswar Rao Vedula

A series of novel, one-pot, four components synthetic procedure has been developed for the synthesis of thioalkylated benzimidazole-linked 4-substituted mercaptoimidazole molecular hybrids and their benzyl derivatives (4a–j) and (5a–f) were synth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4851654741956411e5487269e18520

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A Facile One-Pot Synthesis of Benzimidazole-Linked Pyrrole Structural Motifs via Multicomponent Approach: Design, Synthesis, and Molecular Docking Studies

Autor: Rajeswar Rao Vedula, Akanksha Ashok Sangolkar, Venkatesham Papisetti, Raju Chedupaka

Novel, a series of pyrrolyl-thio alkylated/aryl alkylated benzimidazole derivatives were synthesized via one-pot, the three-component reaction of 5-amino-2-mercaptobenzimidazole, 2,5-dimethoxytetrahydrofuran, and different substituted alkyl/aryl alky

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee294ec82920e733456e4c52493431b

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A facile one-pot, three-component synthesis of a new series of thiazolyl pyrazole carbaldehydes: In vitro anticancer evaluation, in silico ADME/T, and molecular docking studies

Autor: Rajeswar Rao Vedula, Srikanth Mamidala, Raju Chedupaka, Shaik Khajavali, R Kowshik Aravilli, Gondru Ramesh, Vijjulatha Manga

Publikováno v: Journal of Molecular Structure. 1236:130356

A series of thiazolyl pyrazole carbaldehydes (4a-n) were synthesized by conventional method using thiosemicarbazide, substituted phenacyl bromides, substituted 3-acetylcoumarins, and Vilsmeyer-Hack reagent. Structures of all the synthesized compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ac7b3e8e4a3ac940ff85a8d439b4255
https://doi.org/10.1016/j.molstruc.2021.130356

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A facile one-pot, three component synthesis of a new series of 1,3,4-thiadiazines: Anticancer evaluation and molecular docking studies

Autor: Vijjulatha Manga, Rajeswar Rao Vedula, Raju Chedupaka, Srikanth Mamidala, Venugopal Vangala, Saikiran Reddy Peddi

Publikováno v: Journal of Molecular Structure. 1233:130111

A series of new 1,3,4-thiadiazines were synthesized by the conventional method of dehydroacetic acid, thiocarbohydrazide and substituted phenacyl bromides or substituted 3-(2-bromoacetyl) coumarins. Structures of all the synthesized compounds were co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ccd57f63d613b2d76d1652976fb00cd
https://doi.org/10.1016/j.molstruc.2021.130111

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