Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rajsharan K. Rana"'
Publikováno v:
Pharmaceutical Research. :33-36
Recombinant tumor necrosis factor-alpha (TNF), an investigational biological response modifier, is a protein and is susceptible to particulate generation during handling in dilute aqueous solutions. TNF is prone to formation of nonreducible dimers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62016f49f360fc6f42a66f8b8ebad2b0
https://doi.org/10.1023/a:1018919508463
https://doi.org/10.1023/a:1018919508463
Autor:
Richard M. Gilley, Maninder S. Hora, Rajsharan K. Rana, Jack H. Nunberg, Michael E. Hudson, Thomas Robert Tice
Publikováno v:
Nature Biotechnology. 8:755-758
We have evaluated the use of biodegradable poly(DL-lactide-co-glycolide) microspheres for the controlled release of interleukin-2 (IL-2) and its modified forms: succinyl IL-2 (SIL-2) and polyethylene glycol-modified IL-2 (PEG IL-2). We show that a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74bd18cc04ab5d6f7b96cf3aabee54c
https://doi.org/10.1038/nbt0890-755
https://doi.org/10.1038/nbt0890-755
Autor:
Richard M. Gilley, Michael E. Hudson, Thomas R. Tice, Maninder S. Hora, Rajsharan K. Rana, Jack H. Nunberg
Publikováno v:
Pharmaceutical Research. :1190-1194
Human serum albumin (HSA) was encapsulated in a 50:50 copolymer of DL-lactide/glycolide in the form of microspheres. These microspheres were used as a model formulation to study the feasibility of controlling the release of large proteins over a 20-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1f8624da7858bef6f1833d8f4d6856f
https://doi.org/10.1023/a:1015948829632
https://doi.org/10.1023/a:1015948829632