Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rajoshi Chaudhuri"'
Autor:
Gwo-Yu Chuang, Mangaiarkarasi Asokan, Vera B. Ivleva, Amarendra Pegu, Eun Sung Yang, Baoshan Zhang, Rajoshi Chaudhuri, Hui Geng, Bob C. Lin, Mark K. Louder, Krisha McKee, Sijy O’Dell, Hairong Wang, Tongqing Zhou, Nicole A. Doria-Rose, Lisa A. Kueltzo, Q. Paula Lei, John R. Mascola, Peter D. Kwong
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Broadly neutralizing antibodies are showing promise in the treatment and prevention of HIV-1, with several now being evaluated clinically. Some lead clinical candidates, including antibodies CAP256-VRC26.25, N6, PGT121, and VRC07-523, have one or mor
Externí odkaz:
https://doaj.org/article/8b2e6dfe9fd943c5bfd24f8078752346
Autor:
Young D. Kwon, Gwo-Yu Chuang, Baoshan Zhang, Robert T. Bailer, Nicole A. Doria-Rose, Tatyana S. Gindin, Bob Lin, Mark K. Louder, Krisha McKee, Sijy O’Dell, Amarendra Pegu, Stephen D. Schmidt, Mangaiarkarasi Asokan, Xuejun Chen, Misook Choe, Ivelin S. Georgiev, Vivian Jin, Marie Pancera, Reda Rawi, Keyun Wang, Rajoshi Chaudhuri, Lisa A. Kueltzo, Slobodanka D. Manceva, John-Paul Todd, Diana G. Scorpio, Mikyung Kim, Ellis L. Reinherz, Kshitij Wagh, Bette M. Korber, Mark Connors, Lawrence Shapiro, John R. Mascola, Peter D. Kwong
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1798-1809 (2018)
Summary: Highly effective HIV-1-neutralizing antibodies could have utility in the prevention or treatment of HIV-1 infection. To improve the potency of 10E8, an antibody capable of near pan-HIV-1 neutralization, we engineered 10E8-surface mutants and
Externí odkaz:
https://doaj.org/article/20803a2ba97341ed985e9c54c91c448e
Autor:
Kirsten E Lyke, Andrea A Berry, Kaitlin Mason, Azza H Idris, Mark O'Callahan, Myra Happe, Larisa Strom, Nina M Berkowitz, Mercy Guech, Zonghui Hu, Mike Castro, Manjula Basappa, Lu Wang, Kwang Low, LaSonji A Holman, Floreliz Mendoza, Ingelise J Gordon, Sarah H Plummer, Olga Trofymenko, Kathleen S Strauss, Sudhaunshu Joshi, Biraj Shrestha, Matthew Adams, Andrezza Campos Chagas, Jittawadee R Murphy, Judy Stein, Somia Hickman, Andrew McDougal, Bob Lin, Sandeep R Narpala, Sandra Vazquez, Leonid Serebryannyy, Adrian McDermott, Martin R Gaudinski, Edmund V Capparelli, Emily E Coates, Richard L Wu, Julie E Ledgerwood, Lesia K Dropulic, Robert A Seder, Cheryl Young, Colleen Boyce, Jennifer Winkler, Susan Holian, Nancy Greenberg, Shirley George, Alyson Kwon, Brenda Dorsey, Ana Raquel Da Costa, William Witt, Daryl Grays, Arren Gapasin, Paula Bernal, Jeffrey Floyd, Eric Goldstein, Leslie Howe, Myounghee Lee, Jennifer Marron, Kelly Brooks, Lisa Turek, Patricia Farley, Shantel Frels, Delores Booth, Jason Gall, Kevin Carlton, Gabriela Albright, Nadia Amharref, Kandace Atallah, Sashikanth Banappagari, Niutish Bastani, Daniel Blackstock, Bobby Boonyaratanakornkit, Elizabeth Carey, Adam Charlton, Rajoshi Chaudhuri, Alegria M. Caringal, Mingzhong Chen, Peifeng Chen, Wei Cheng, Daniel Gowetski, Krishana Gulla, Erica Hastings, Joe Horwitz, Vera Ivleva, Dan Kordella, Lisa A. Kueltzo, Sara Lagler, Matt Le, James Lee, Paula Lei, Yile Li, Attila Nagy, Aakash Patel, Peyi Runsewe, Will Shadrick, Shamitha Shetty, Hairong Wang, Calvin Webber, Farah Vejzagic, Yoo-Jung Yang
Publikováno v:
The Lancet Infectious Diseases. 23:578-588
Autor:
Emily E Coates, Srilatha Edupuganti, Grace L Chen, Myra Happe, Larisa Strom, Alicia Widge, Maria Burgos Florez, Josephine H Cox, Ingelise Gordon, Sarah Plummer, Abidemi Ola, Galina Yamshchikov, Charla Andrews, Sharon Curate-Ingram, Patricia Morgan, Shashi Nagar, Matthew H Collins, Amy Bray, Thuy Nguyen, Judy Stein, Christopher L Case, Florence Kaltovich, Diane Wycuff, C Jason Liang, Kevin Carlton, Sandra Vazquez, John R Mascola, Julie E Ledgerwood, Ellie Butler, Jean Winter, Jianguo Xu, Amy Sherman, Colleen Kelley, Rameses Fredrick, Nadine Rouphael, Varun Phadke, Cynthia Whitney, Alicarmen Alvarez, Renata Dennis, Rebecca Fineman, Pamela Lankford-Turner, Sha Yi, Lilin Lai, Gena Burch, Shanker Gupta, Nina Berkowitz, Cristina Carter, Allison Beck, Brenda Larkin, Stephanie Taylor, Mandy Alger, Jessica Bahorich, Amy Lynch Chamberlain, Ya-chen Chang, Rajoshi Chaudhuri, Jonathan Cooper, Jacob Demirji, Fan Yang, Alissa Fernald, Deepika Gollapudi, Janel Holland-Linn, Lisa Kueltzo, James Lee, Jie Liu, Xun Liu, Rachel Mowery, Sarah O'Connell, Erwin Rosales-Zavala, Jason Sands, Xin Wang, Shaojie Weng, Sara Witter
Publikováno v:
The Lancet. Infectious diseases. 22(8)
Western (WEEV), eastern (EEEV), and Venezuelan (VEEV) equine encephalitis viruses are mosquito-borne pathogens classified as potential biological warfare agents for which there are currently no approved human vaccines or therapies. We aimed to evalua
Autor:
Bob C. Lin, Amarendra Pegu, Eun Sung Yang, Nicole A. Doria-Rose, Peter D. Kwong, Hui Geng, Lisa A. Kueltzo, Mangaiarkarasi Asokan, Hairong Wang, Rajoshi Chaudhuri, Krisha McKee, Q. Paula Lei, Gwo-Yu Chuang, Tongqing Zhou, Sijy O'Dell, John R. Mascola, Mark K. Louder, Baoshan Zhang, Vera B. Ivleva
Publikováno v:
mAbs. 12
Broadly neutralizing antibodies are showing promise in the treatment and prevention of HIV-1, with several now being evaluated clinically. Some lead clinical candidates, including antibodies CAP256-VRC26.25, N6, PGT121, and VRC07-523, have one or mor
Autor:
Ivelin S. Georgiev, Diana G. Scorpio, Peter D. Kwong, Robert T. Bailer, John R. Mascola, Nicole A. Doria-Rose, Mangaiarkarasi Asokan, Young Do Kwon, Slobodanka D. Manceva, Kshitij Wagh, Baoshan Zhang, Krisha McKee, Vivian Jin, Mikyung Kim, Xuejun Chen, Misook Choe, Lisa A. Kueltzo, John-Paul Todd, Marie Pancera, Mark K. Louder, Sijy O'Dell, Reda Rawi, Tatyana Gindin, Ellis L. Reinherz, Rajoshi Chaudhuri, Stephen D. Schmidt, Lawrence Shapiro, Gwo-Yu Chuang, Bette Korber, Keyun Wang, Bob C. Lin, Amarendra Pegu, Mark Connors
Publikováno v:
Cell reports
Cell Reports, Vol 22, Iss 7, Pp 1798-1809 (2018)
Cell Reports, Vol 22, Iss 7, Pp 1798-1809 (2018)
SUMMARY Highly effective HIV-1-neutralizing antibodies could have utility in the prevention or treatment of HIV-1 infection. To improve the potency of 10E8, an antibody capable of near pan-HIV-1 neutralization, we engineered 10E8-surface mutants and
Autor:
C. Russell Middaugh, Neha Sahni, John M. Hickey, Sangeeta B. Joshi, Rajoshi Chaudhuri, Andrew Metters, David B. Volkin, Ajit Joseph M. D'Souza
Publikováno v:
Protein Science. 26:527-535
Continuous glucose monitoring (CGM) devices offer diabetes patients a convenient approach to assist in controlling blood glucose levels. A prototype CGM has been developed that uses the emission profile of a polarity-sensitive fluorophore (acrylodan)
Autor:
Ernesto Freire, Benjamin R. Clarkson, Lisa A. Kueltzo, Arne Schön, Jonathan W. Cooper, Rajoshi Chaudhuri
Publikováno v:
Analytical biochemistry. 554
Different factors affect the long term stability of monoclonal antibodies, among them denaturation or partial denaturation that is often followed by aggregation. Isothermal calorimetry is capable of quantifying the kinetics of denaturation/aggregatio
Autor:
Misook Choe, Aliaksandr Druz, Joseph R. Francica, M. Gordon Joyce, Peter D. Kwong, Robert A. Seder, Leonard W. Seymour, Michal Pechar, Lisa A. Kueltzo, Richard Laga, Rajoshi Chaudhuri, Mallika Sastry, Man Chen, Geoffrey M. Lynn, Kaitlyn M. Morabito, Kiyoon Ko, Ivelin S. Georgiev, John R. Mascola, Barney S. Graham, Baoshan Zhang, Tracy J. Ruckwardt
Publikováno v:
Bioconjugate chemistry. 27(10)
Structure-based vaccine design has been used to develop immunogens that display conserved neutralization sites on pathogens such as HIV-1, respiratory syncytial virus (RSV), and influenza. Improving the immunogenicity of these designed immunogens wit
Autor:
Neha Sahni, Sangeeta B. Joshi, Prakash Manikwar, John M. Hickey, Ajit Joseph M. D'Souza, C. Russell Middaugh, David B. Volkin, Rajoshi Chaudhuri, Andrew Metters
Publikováno v:
Journal of pharmaceutical sciences. 106(5)
This study describes the physicochemical characterization, stabilization, and formulation design of SM4-AC, an acrylodan-labeled glucose/galactose-binding protein for use in a continuous glucose monitoring device. The physical stability profile of SM