Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Rajnish Kumar, Singh"'
Publikováno v:
Cell Insight, Vol 3, Iss 6, Pp 100200- (2024)
Hypoxic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) refers to the phenomenon under low oxygen where the virus goes from latent to lytic replication. Typically, healthy cells generally cease cell division and DNA replication under h
Externí odkaz:
https://doaj.org/article/f2834e07831240e5bebabdf8d5e0bf06
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTHypoxia results from an insufficient supply of oxygen, which results in physiological stress in biological systems. Cells respond to this unfavorable condition by reducing critical cellular functions, which include replication, transcription,
Externí odkaz:
https://doaj.org/article/5d768f5039574388977290b5352668f5
Hunting of hunted: an ensemble modeling approach to evaluate suitable habitats for caracals in India
Autor:
Ashish Kumar Jangid, Chandra Prakash Singh, Jai Singh Parihar, Jasbir Singh Chauhan, Rajnish Kumar Singh, Prakash Kumar Verma, Amritanshu Singh, Shantanu Sharma, Shekhar Kolipaka
Publikováno v:
Ecological Processes, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Large-scale hunting and various anthropogenic pressures in the recent past have pushed the Asiatic caracal (Caracal caracal schmitzi), an elusive medium-sized and locally threatened felid species towards local extinction in India.
Externí odkaz:
https://doaj.org/article/e47ddbbf05344355b6eb4167cd11edac
Autor:
Misbahuddin M Rafeeq, Alaa Hamed Habib, Alaa F. Nahhas, Najat Binothman, Majidah Aljadani, Jawaher Almulhim, Ziaullah M Sain, Mohammad Zubair Alam, Norah A Alturki, Qamre Alam, Manish Manish, Rajnish Kumar Singh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Kaposi’s sarcoma associated herpesvirus (KSHV) is causative agent of Kaposi’s sarcoma, Multicentric Castleman Disease and Pleural effusion lymphoma. KSHV-encoded ORF17 encodes a protease which cleaves -Ala-Ala-, -Ala-Ser- or -Ala-Thr-bonds. The p
Externí odkaz:
https://doaj.org/article/713c3756c12c4c7f97de7867b3dd812d
Autor:
Rajnish Kumar Singh, Yonggang Pei, Dipayan Bose, Zachary L Lamplugh, Kunfeng Sun, Yan Yuan, Paul Lieberman, Jianxin You, Erle S Robertson
Publikováno v:
eLife, Vol 10 (2021)
The cellular adaptive response to hypoxia, mediated by high HIF1α levels includes metabolic reprogramming, restricted DNA replication and cell division. In contrast to healthy cells, the genome of cancer cells, and Kaposi’s sarcoma associated herp
Externí odkaz:
https://doaj.org/article/4cb01fb50cda4de298ad1eeae6fd5e1a
Autor:
Gopinath Prakasam, Mohammad Askandar Iqbal, Anusha Srivastava, Rameshwar N. K. Bamezai, Rajnish Kumar Singh
Publikováno v:
VirusDisease. 33:223-235
The molecular basis of human papillomavirus (HPV)-mediated cellular immortalization and malignant transformation has illustrated an indispensable role of viral E6/E7-oncoproteins. However, the impact of viral-oncoproteins on the metabolic phenotype o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cfada83aee3306b929d527840746d1
https://doi.org/10.1007/s13337-022-00776-w
https://doi.org/10.1007/s13337-022-00776-w
Autor:
Rajnish Kumar Singh, Zachary L Lamplugh, Fengchao Lang, Yan Yuan, Paul Lieberman, Jianxin You, Erle S Robertson
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008025 (2019)
Kaposi's sarcoma associated herpesvirus (KSHV), like all herpesviruses maintains lifelong persistence with its host genome in latently infected cells with only a small fraction of cells showing signatures of productive lytic replication. Modulation o
Externí odkaz:
https://doaj.org/article/8396c47177b7425a9c05b554a87d5fd2
Autor:
Fengchao Lang, Rajnish Kumar Singh, Yonggang Pei, Shengwei Zhang, Kunfeng Sun, Erle S Robertson
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007796 (2019)
Epstein-Barr virus (EBV) is a ubiquitous oncogenic virus that induces many cancers. N6-Methyladenosine (m6A) modification regulates many cellular processes. We explored the role of m6A in EBV gene regulation and associated cancers. We have comprehens
Externí odkaz:
https://doaj.org/article/3e8ca476f6d04d2f9e08e0e7706febd8
Autor:
Fengchao Lang, Zhiguo Sun, Yonggang Pei, Rajnish Kumar Singh, Hem Chandra Jha, Erle S Robertson
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007732 (2019)
[This corrects the article DOI: 10.1371/journal.ppat.1007253.].
Externí odkaz:
https://doaj.org/article/f83fcba155724f059f90e8daf3e67953
Autor:
Shengwei Zhang, Yonggang Pei, Fengchao Lang, Kunfeng Sun, Rajnish Kumar Singh, Zachary L Lamplugh, Abhik Saha, Erle S Robertson
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007514 (2019)
EBV latent antigen 3C (EBNA3C) is essential for EBV-induced primary B-cell transformation. Infection by EBV induces hypermethylation of a number of tumor suppressor genes, which contributes to the development of human cancers. The Ras association dom
Externí odkaz:
https://doaj.org/article/e560d5532aec4e76b872e9123a657c68