Výsledky vyhledávání - "Rajni K, Sharma"

Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity

Autor: Gyles E, Cozier, Sylva L, Schwager, Rajni K, Sharma, Kelly, Chibale, Edward D, Sturrock, K Ravi, Acharya

Publikováno v: The Febs Journal

Angiotensin‐1‐converting enzyme (ACE) is a zinc metallopeptidase that consists of two homologous catalytic domains (known as nACE and cACE) with different substrate specificities. Based on kinetic studies it was previously reported that sampatril

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7678c1617aea72f4a4979b9a13be455c
https://pubmed.ncbi.nlm.nih.gov/29476645

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Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors

Autor: Ross G, Douglas, Rajni K, Sharma, Geoffrey, Masuyer, Lizelle, Lubbe, Ismael, Zamora, K Ravi, Acharya, Kelly, Chibale, Edward D, Sturrock

Publikováno v: Clinical Science (London, England : 1979)

ACE (angiotensin-1-converting enzyme) is a zinc metallopeptidase that plays a prominent role in blood pressure regulation and electrolyte homeostasis. ACE consists of two homologous domains that despite similarities of sequence and topology display d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2486e90c658bb398563bf4c1681f8eeb
https://pubmed.ncbi.nlm.nih.gov/24015848

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Akademický článek

Crystal structures of sampatrilat and sampatrilat‐Asp in complex with human ACE – a molecular basis for domain selectivity.

Autor: Cozier, Gyles E.¹, Schwager, Sylva L.², Sharma, Rajni K.³, Chibale, Kelly³, Sturrock, Edward D.², Acharya, K. Ravi¹ bsskra@bath.ac.uk

Publikováno v: FEBS Journal. Apr2018, Vol. 285 Issue 8, p1477-1490. 14p.

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Akademický článek

Dynamics of O-induced reactions using Ni, Ge and Mo targets.

Autor: Rajni, Kaur, Gurvinder, Sharma, Manoj K.

Publikováno v: International Journal of Modern Physics E: Nuclear Physics; Nov2016, Vol. 25 Issue 11, p-1, 17p

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Akademický článek

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors.

Autor: DOUGLAS, Ross G., SHARMA, Rajni K., MASUYER, Geoffrey, LUBBE, Lizelle, ZAMORA, Ismael, Ravi ACHARYA, K., CHIBALE, Kelly, STURROCK, Edward D.

Publikováno v: Clinical Science; Feb2014, Vol. 126 Issue 4, following p305-313, 13p

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Akademický článek

New ketomethylene inhibitor analogues: synthesis and assessment of structural determinants for N-domain selective inhibition of angiotensin-converting enzyme.

Autor: Sharma, Rajni K., Douglas, Ross G., Louw, Stefan, Chibale, Kelly, Sturrock, Edward D.

Publikováno v: Biological Chemistry; Jun2012, Vol. 393 Issue 6, p485-493, 9p, 7 Diagrams, 2 Charts, 1 Graph

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Effect of Fe doping on dielectric, ferroelectric and pyroelectric properties of PLZT (8/65/35).

Autor: Md Ahamad, Mohiddon and, K L Yadav

Publikováno v: Journal of Physics D: Applied Physics; Dec2007, Vol. 40 Issue 23, p7540-7547, 8p

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Akademický článek

Masthead.

Publikováno v: Biological Chemistry; Jun2012, Vol. 393 Issue 6, pi-iii, 3p

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