Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Rajiv Pathak"'
Autor:
Saloni Malla, Angelique Nyinawabera, Rabin Neupane, Rajiv Pathak, Donghyun Lee, Mariam Abou-Dahech, Shikha Kumari, Suman Sinha, Yuan Tang, Aniruddha Ray, Charles R. Ashby, Mary Qu Yang, R. Jayachandra Babu, Amit K. Tiwari
Publikováno v:
Cancers, Vol 16, Iss 15, p 2621 (2024)
Apoptosis induction with taxanes or anthracyclines is the primary therapy for TNBC. Cancer cells can develop resistance to anticancer drugs, causing them to recur and metastasize. Therefore, non-apoptotic cell death inducers could be a potential trea
Externí odkaz:
https://doaj.org/article/2814ea56bf34434c8ee370ac2e0f41ec
Publikováno v:
Vaccines, Vol 12, Iss 5, p 459 (2024)
Understanding the antibody response to SARS-CoV-2, the virus responsible for COVID-19, is crucial to comprehending disease progression and the significance of vaccine and therapeutic development. The emergence of highly contagious variants poses a si
Externí odkaz:
https://doaj.org/article/d099ab19b39e475a97e513c3f8fde737
Publikováno v:
Biology, Vol 13, Iss 5, p 307 (2024)
Cancer immune evasion represents a leading hallmark of cancer, posing a significant obstacle to the development of successful anticancer therapies. However, the landscape of cancer treatment has significantly evolved, transitioning into the era of im
Externí odkaz:
https://doaj.org/article/74c5b7dd0fa34af9b6e0371bd9e0105a
Autor:
Rajiv Pathak, Carolina Eliscovich, Ignacio Mena, Anastasija Cupic, Magdalena Rutkowska, Kartik Chandran, Rohit K. Jangra, Adolfo García-Sastre, Robert H. Singer, Ganjam V. Kalpana
Publikováno v:
Viruses, Vol 16, Iss 2, p 262 (2024)
SARS-CoV-2 infection remains a global burden. Despite intensive research, the mechanism and dynamics of early viral replication are not completely understood, such as the kinetics of the formation of genomic RNA (gRNA), sub-genomic RNA (sgRNA), and r
Externí odkaz:
https://doaj.org/article/5eb3557e958b465e866222b03412dab6
Autor:
Rajiv Pathak
Publikováno v:
Viruses, Vol 15, Iss 11, p 2216 (2023)
G-quadruplexes (G4s) are unique non-canonical four-stranded nucleic acid secondary structures formed by guanine-rich DNA or RNA sequences. Sequences with the potential to form quadruplex motifs (pG4s) are prevalent throughout the genomes of all organ
Externí odkaz:
https://doaj.org/article/b44d0307d564462b860d2a1446425224
Autor:
Vidhya Rajalakshmi V, Akilandeswari Ramu, Jayaprakash Chinnappan, Palanivel Velmurugan, Rajiv Pathak, Rami Adel Pashameah, Atif Abdulwahab A Oyouni, Osama M Al-Amer, Mohammed I Alasseiri, Abdullah Hamadi, Mansuor A Alanazi, Thangavelu Sathiamoorthi
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282263 (2023)
COVID-19 caused by the SARS-CoV-2 virus is widespread in all regions, and it disturbs host immune system functioning leading to extreme inflammatory reaction and hyperactivation of the immune response. Kabasura Kudineer (KSK) is preventive medicine a
Externí odkaz:
https://doaj.org/article/3153d7b438474ccf84e04af9e6b06050
Autor:
Updesh Dixit, Savita Bhutoria, Xuhong Wu, Liming Qiu, Menachem Spira, Sheeba Mathew, Richard Harris, Lucas J. Adams, Sean Cahill, Rajiv Pathak, P. Rajesh Kumar, Minh Nguyen, Seetharama A. Acharya, Michael Brenowitz, Steven C. Almo, Xiaoqin Zou, Alasdair C. Steven, David Cowburn, Mark Girvin, Ganjam V. Kalpana
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
HIV-1 integrase (IN) binds the host factor INI1/SMARCB1, which is required at multiple stages of HIV-1 replication. Here, the authors show that the same IN residues are involved in INI1 and RNA binding and in influencing particle morphogenesis and su
Externí odkaz:
https://doaj.org/article/b8bafab2f92543e6a097c5d975bbcf2d
Publikováno v:
Dermatologica Sinica, Vol 34, Iss 2, Pp 67-73 (2016)
Acne vulgaris, a prevalent disorder of the skin, is found to increase the incidence of suicidal ideation in acne patients (∼7.1%). This creates a dilemma in the mind whether acne is a life threatening disease among humans. The main inducer for this
Externí odkaz:
https://doaj.org/article/ccc33fd09c7441279a36983dfd777cbd
Autor:
Rajiv Pathak, Carolina Eliscovich, Ignacio Mena, Updesh Dixit, Adolfo García-Sastre, Robert H Singer, Ganjam V. Kalpana
Publikováno v:
bioRxiv
SARS-CoV-2 infection has caused a major global burden. Despite intensive research, the mechanism and dynamics of early viral replication are not completely understood including the kinetics of formation of plus stranded genomic and subgenomic RNAs (g
Autor:
Joseph Flemish, Robert Armitage, Zhongmin Ren, Wouter Soer, Hossein Lotfi, Theodore Chung, Rajiv Pathak, Hee Jin Kim, Brendan Moran, Willem Sillevis Smitt, Jia Cheng Tan, Yongxiang Melvin Tio, Reich Distor, Shimin Lim, Kheng Boo Lim, Anant Vaidyanathan, Oleg Shchekin
Publikováno v:
SID Symposium Digest of Technical Papers. 53:478-480