Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rajiv Bajracharya"'
Autor:
Rajiv Bajracharya, Jae Geun Song, Basavaraj Rudragouda Patil, Sang Hoon Lee, Hye-Mi Noh, Da-Hyun Kim, Gyu-Lin Kim, Soo-Hwa Seo, Ji-Won Park, Seong Hoon Jeong, Chang Hoon Lee, Hyo-Kyung Han
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1959-1970 (2022)
Conventional chemotherapy lacking target selectivity often leads to severe side effects, limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both selective drug release and efficient intracellular uptake at the targe
Externí odkaz:
https://doaj.org/article/d15a766aca784877a021b0620ec4f8c0
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1290-1308 (2019)
Advancements in biotechnology and protein engineering expand the availability of various therapeutic proteins including vaccines, antibodies, hormones, and growth factors. In addition, protein drugs hold many therapeutic advantages over small synthet
Externí odkaz:
https://doaj.org/article/a46e094bbc8a496986ece6a086630591
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1510 (2022)
This study aimed to develop a solid dispersion (SD) of MT-102, a new anti-inflammatory agent, to improve its oral bioavailability. The ternary SD formulations of MT-102 (a poorly soluble extract of Isatis indigotica and Juglans mandshurica) were prep
Externí odkaz:
https://doaj.org/article/5219403c3aa3498fad653e526e63f93d
Autor:
Kshitis Chandra Baral, Jae-Geun Song, Sang Hoon Lee, Rajiv Bajracharya, Godesi Sreenivasulu, Minkyoung Kim, Kyeong Lee, Hyo-Kyung Han
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1142 (2021)
AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effectiv
Externí odkaz:
https://doaj.org/article/fc543c62f2b846f6baeba4a59a00f363
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 853 (2020)
Tablet film coating is a common but critical process providing various functionalities to tablets, thereby meeting diverse clinical needs and increasing the value of oral solid dosage forms. Tablet film coating is a technology-driven process and the
Externí odkaz:
https://doaj.org/article/9c3a0d4ca1674c5ead700d2355cf5d58
Publikováno v:
Pharmaceutics, Vol 12, Iss 1, p 68 (2020)
Colon targeted drug delivery systems have gained a great deal of attention as potential carriers for the local treatment of colonic diseases with reduced systemic side effects and also for the enhanced oral delivery of various therapeutics vulnerable
Externí odkaz:
https://doaj.org/article/fc8ed900c95c47d0b922a109a4d26ac9
Publikováno v:
Pharmaceutics, Vol 11, Iss 5, p 206 (2019)
LW6 (3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-4-hydroxy-benzoic acid methyl ester) is a potent inhibitor of drug efflux by the breast cancer resistance protein (BCRP). However, its poor aqueous solubility leads to low bioavailability, which curre
Externí odkaz:
https://doaj.org/article/a4f898f1b53842079319b505629d6bea
Publikováno v:
International Journal of Nanomedicine
Probiotics have demonstrated their high potential to treat and/or prevent various diseases including neurodegenerative disorders, cancers, cardiovascular diseases, and inflammatory diseases. Probiotics are also effective against multidrug-resistant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c036e167bf9174a61a926c2ea20c3c64
https://doi.org/10.2147/ijn.s337427
https://doi.org/10.2147/ijn.s337427
Autor:
Rajiv Bajracharya, Jae Geun Song, Kshitis Chandra Baral, Hyo-Kyung Han, Kyeong Lee, Minkyoung Kim, Godesi Sreenivasulu, Sang Hoon Lee
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1142, p 1142 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1142, p 1142 (2021)
AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c723ecee41b4d5be76c2e6b06b673a20
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1290-1308 (2019)
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1290-1308 (2019)
Advancements in biotechnology and protein engineering expand the availability of various therapeutic proteins including vaccines, antibodies, hormones, and growth factors. In addition, protein drugs hold many therapeutic advantages over small synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508aab8cb93e4a2e1390ebbb72a68804
https://pubmed.ncbi.nlm.nih.gov/31921395
https://pubmed.ncbi.nlm.nih.gov/31921395