Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Rajini Rao"'
Autor:
Monish Ram Makena, Myungjun Ko, Allatah X. Mekile, Nanami Senoo, Donna K. Dang, John Warrington, Phillip Buckhaults, C. Conover Talbot, Jr., Steven M. Claypool, Rajini Rao
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102240- (2022)
A complex interplay between the extracellular space, cytoplasm and individual organelles modulates Ca2+ signaling to impact all aspects of cell fate and function. In recent years, the molecular machinery linking endoplasmic reticulum stores to plasma
Externí odkaz:
https://doaj.org/article/0b300ccbdec4497a989595ebae280235
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67348 (2013)
An unconventional interaction between SPCA2, an isoform of the Golgi secretory pathway Ca(2+)-ATPase, and the Ca(2+) influx channel Orai1, has previously been shown to contribute to elevated Ca(2+) influx in breast cancer derived cells. In order to i
Externí odkaz:
https://doaj.org/article/b97c1b303e6d4c74b5a9e7805f9e1dbf
Autor:
Christopher L Brett, Laura Kallay, Zhaolin Hua, Richard Green, Anthony Chyou, Yongqiang Zhang, Todd R Graham, Mark Donowitz, Rajini Rao
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17619 (2011)
Protons, the smallest and most ubiquitous of ions, are central to physiological processes. Transmembrane proton gradients drive ATP synthesis, metabolite transport, receptor recycling and vesicle trafficking, while compartmental pH controls enzyme fu
Externí odkaz:
https://doaj.org/article/4c4a7e183a0740b890c3fc5bd8256877
Autor:
Yong-Qiang Zhang, Soledad Gamarra, Guillermo Garcia-Effron, Steven Park, David S Perlin, Rajini Rao
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000939 (2010)
Ergosterol is an important constituent of fungal membranes. Azoles inhibit ergosterol biosynthesis, although the cellular basis for their antifungal activity is not understood. We used multiple approaches to demonstrate a critical requirement for erg
Externí odkaz:
https://doaj.org/article/338942a9cc30421e8fbea7327d77f316
Autor:
Rajini Rao, Manuj Bandral, Myungjun Ko, Hari Prasad, José P. Llongueras, Monish Ram Makena, Donna K. Dang
Legend for Supplementary Movies 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c255bcfa157e1b4857ad10a3b286e9
https://doi.org/10.1158/1541-7786.22516020
https://doi.org/10.1158/1541-7786.22516020
Autor:
Rajini Rao, Manuj Bandral, Myungjun Ko, Hari Prasad, José P. Llongueras, Monish Ram Makena, Donna K. Dang
Progression of benign tumors to invasive, metastatic cancer is accompanied by the epithelial-to-mesenchymal transition (EMT), characterized by loss of the cell-adhesion protein E-cadherin. Although silencing mutations and transcriptional repression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e19104671f9050452d231db287ce7af
https://doi.org/10.1158/1541-7786.c.6541257
https://doi.org/10.1158/1541-7786.c.6541257
Publikováno v:
Cancer Metastasis Rev
Extracellular acidification is a well-known driver of tumorigenesis that has been extensively studied. In contrast, the role of endosomal pH is novel and relatively unexplored. There is emerging evidence from a growing number of studies showing that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762dd53411a6c1ae3fca18ea0f9186cc
https://doi.org/10.1007/s10555-020-09870-1
https://doi.org/10.1007/s10555-020-09870-1
Autor:
Myungjun Ko, Monish R Makena, Paula Schiapparelli, Paola Suarez-Meade, Allatah X Mekile, Bachchu Lal, Hernando Lopez-Bertoni, Kristen L Kozielski, Jordan J Green, John Laterra, Alfredo Quiñones-Hinojosa, Rajini Rao
Publikováno v:
PNAS nexus. 1(1)
A small population of self-renewing stem cells initiate tumors and maintain therapeutic resistance in glioblastoma (GBM). Given the limited treatment options and dismal prognosis for this disease, there is urgent need to identify drivers of stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e791567b83f5e9bd614247d99900f3
https://pubmed.ncbi.nlm.nih.gov/35387234
https://pubmed.ncbi.nlm.nih.gov/35387234