Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Rajeshwari R Mehta"'
Autor:
Rajendra G Mehta, Michael Hawthorne, Rajeshwari R Mehta, Karen E O Torres, Xinjian Peng, David L McCormick, Levy Kopelovich
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113175 (2014)
The present experiments were performed to determine the roles of estrogen receptors α and β (ERα and ERβ) in normal and neoplastic development in the mouse mammary gland. In wild-type mice, in vivo administration of estradiol (E) + progesterone (
Externí odkaz:
https://doaj.org/article/f6a1e2f7d1444543bd7e20b6d9243513
Autor:
Akash, Gupta, Geetanjali, Gupta, Rajeshwari R, Mehta, David Z, Ivancic, Rashidra R, Walker, Jankiben R, Patel, Karen M, Gallegos, A Michael, Davidson, Seema A, Khan, Rajendra G, Mehta, Syreeta L, Tilghman
Publikováno v:
Biology Open
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Mouse mammary organ culture (MMOC) is used to evaluate the efficacy of chemopreventive agents against the development of carcinogen-induced preneoplastic lesions and is highly correlative to in vivo carcinogenesis models. Here, we developed a new ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08a7e8193b112d49e67c17e1987ca12f
https://pubmed.ncbi.nlm.nih.gov/32366373
https://pubmed.ncbi.nlm.nih.gov/32366373
Autor:
Amit Kalra, Sarbani Roy, Levy Kopelovich, Rajeshwari R. Mehta, Michael Hawthorne, Fatouma Alimirah, Rajendra G. Mehta, Xinjian Peng
Publikováno v:
Molecular and Cellular Biochemistry. 372:249-256
The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) plays a central role in regulating metabolism, including interaction with the estrogen receptor-α (ERα). Significantly, PPARγ activity can be modulated by small molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aba1eccbd66e097f36ac915e04c824f
https://doi.org/10.1007/s11010-012-1466-9
https://doi.org/10.1007/s11010-012-1466-9
Autor:
Richard V. Benya, Rajendra G. Mehta, Genoveva Murillo, Nishant Tiwari, Sarbani Roy, Rajeshwari R. Mehta, Xinjian Peng, Liang Yuan
Publikováno v:
Journal of Endocrinology. 212:207-215
CYP24is a well-established vitamin D receptor (VDR) target gene. The active VDR ligand 1,25(OH)2D3regulates its own catabolism by increasingCYP24expression. It is well known that in the presence of 1,25(OH)2D3, VDR binds to VDREs in the promoter regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec5dfbed904d08b222dca56737c3d4d
https://doi.org/10.1530/joe-11-0305
https://doi.org/10.1530/joe-11-0305
Autor:
Fatima Lekmine, Craig W. Beattie, Tohru Yamada, Dibyen Majumdar, Marissa L. King, Rajeshwari R. Mehta, Tapas K. Das Gupta, Albert Green, Anne Shilkaitis, Konstantin Christov, Laura Bratescu
Publikováno v:
Molecular Cancer Therapeutics. 8:2947-2958
We report that amino acids 50 to 77 of azurin (p28) preferentially enter the human breast cancer cell lines MCF-7, ZR-75-1, and T47D through a caveolin-mediated pathway. Although p28 enters p53 wild-type MCF-7 and the isogenic p53 dominant-negative M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5c4555492731c20566b89ff748db62
https://doi.org/10.1158/1535-7163.mct-09-0444
https://doi.org/10.1158/1535-7163.mct-09-0444
Autor:
Craig W. Beattie, Tohru Yamada, Albert Green, Anne Shilkaitis, Brad N. Taylor, Konstantin Christov, Laura Bratescu, Tapas K. Das Gupta, Ananda M. Chakrabarty, Fatima Lekmine, Rajeshwari R. Mehta
Publikováno v:
Cancer Research. 69:537-546
Azurin, a member of the cupredoxin family of copper containing redox proteins, preferentially penetrates human cancer cells and exerts cytostatic and cytotoxic (apoptotic) effects with no apparent activity on normal cells. Amino acids 50 to 77 (p28)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffe2e50dd58736f92230ceec3d71f1b
https://doi.org/10.1158/0008-5472.can-08-2932
https://doi.org/10.1158/0008-5472.can-08-2932
Autor:
Philip S. Boerner, Rajendra G. Mehta, Rajeshwari R. Mehta, Srinivasan Vijayakumar, Satyaseelan Packianathan, Tapas K. Das Gupta
Publikováno v:
The Cancer Journal. 12:445-450
This article comprehensively reviews the clinical trials and considers the future directions of the use of vitamin D and its analogs in the treatment or chemoprevention of breast cancer. Chemopreventive treatment strategies strive to delay the onset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c25831ea9e9ea6958b3269e28beb3e9
https://doi.org/10.1097/00130404-200611000-00001
https://doi.org/10.1097/00130404-200611000-00001
Publikováno v:
International Journal of Cancer. 108:922-929
We previously showed that a new vitamin D analog, 1α(OH)D5 (D5), induced differentiation and inhibited the growth of breast cancer cells. In this report, we examined whether D5 specifically delivered to breast cancer cells could have any therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1108ac646bbff462fd72164734d4fd2
https://doi.org/10.1002/ijc.11590
https://doi.org/10.1002/ijc.11590
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. :253-264
Numerous analogs of Vitamin D have been synthesized in recent years with the hope of generating a compound that retains the anticarcinogenic activity of Vitamin D without causing any toxicity. We synthesized such an analog, 1alpha-hydroxy-24-ethylcho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4b8b4a4cf6f1c6b98b7e936261690e
https://doi.org/10.1016/s0027-5107(02)00341-x
https://doi.org/10.1016/s0027-5107(02)00341-x
Autor:
Levy Kopelovich, Karen E. O. Torres, Xinjian Peng, Rajendra G. Mehta, Rajeshwari R. Mehta, Michael Hawthorne, David L. McCormick
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113175 (2014)
PLoS ONE
PLoS ONE
The present experiments were performed to determine the roles of estrogen receptors α and β (ERα and ERβ) in normal and neoplastic development in the mouse mammary gland. In wild-type mice, in vivo administration of estradiol (E) + progesterone (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030ebf3be901ffa8f30abaa65ac9b41f
https://doaj.org/article/f6a1e2f7d1444543bd7e20b6d9243513
https://doaj.org/article/f6a1e2f7d1444543bd7e20b6d9243513