Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Rajesh T, Gandhi"'
Autor:
Tamlyn A. Rautenberg, Shu Kay Ng, Gavin George, Mahomed-Yunus S. Moosa, Suzanne M. McCluskey, Rebecca F. Gilbert, Selvan Pillay, Isaac Aturinda, Kevin L. Ard, Winnie R. Muyindike, Nicholas Musinguzi, Godfrey Masette, Melendhran Pillay, Pravi Moodley, Jaysingh Brijkumar, Rajesh T. Gandhi, Brent Johnson, Henry Sunpath, Mwebesa B. Bwana, Vincent C. Marconi, Mark J. Siedner
Publikováno v:
Health and Quality of Life Outcomes, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Background Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one third initiating first-line treatment experience virological failure and the determinants of
Externí odkaz:
https://doaj.org/article/d2b188a0d0b546e59e050e2059d1f1ea
Autor:
Dennis C. Copertino Jr., Carissa S. Holmberg, Jared Weiler, Adam R. Ward, J. Natalie Howard, Callie Levinger, Alina P.S. Pang, Michael J. Corley, Friederike Dündar, Paul Zumbo, Doron Betel, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, Noemi Linden, Bernard J. Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, Colin Kovacs, Erika Benko, Alberto Bosque, R. Brad Jones, for the AIDS Clinical Trials Group (ACTG) A5321 Team
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
IL-15 is under clinical investigation toward the goal of curing HIV infection because of its abilities to reverse HIV latency and enhance immune effector function. However, increased potency through combination with other agents may be needed. 3-Hydr
Externí odkaz:
https://doaj.org/article/ed18029fbf2043e591567763be3f9138
Autor:
Melissa A. Tosiano, Hanna Mar, Dianna Hoeth, Joseph J. Eron, Rajesh T. Gandhi, Deborah K. McMahon, Ronald J. Bosch, John W. Mellors, Joshua C. Cyktor
Publikováno v:
Journal of Virus Eradication, Vol 8, Iss 4, Pp 100095- (2022)
Background: The ability of automated, FDA-cleared plasma HIV-1 RNA assays to detect low-level viremia, compared to manual, highly sensitive research-only methods, is not well-defined. We therefore tested paired plasma samples from people with HIV-1 (
Externí odkaz:
https://doaj.org/article/8ab1738fb15a4690a699c45cc74ef7b0
Autor:
Geoffrey T. Ivison, Elena Vendrame, Giovanny J. Martínez-Colón, Thanmayi Ranganath, Rosemary Vergara, Nancy Q. Zhao, Maureen P. Martin, Sean C. Bendall, Mary Carrington, Joshua C. Cyktor, Deborah K. McMahon, Joseph Eron, R. Brad Jones, John W. Mellors, Ronald J. Bosch, Rajesh T. Gandhi, Susan Holmes, Catherine A. Blish, The ACTG 5321 Team
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The latent HIV-1 reservoir represents a major barrier to achieving a long-term antiretroviral therapy (ART)-free remission or cure for HIV-1. Natural Killer (NK) cells are innate immune cells that play a critical role in controlling viral infections
Externí odkaz:
https://doaj.org/article/c25a0532cc3d486983f8f67d814dd06a
Publikováno v:
Southern African Journal of HIV Medicine, Vol 22, Iss 1, Pp e1-e4 (2021)
In many ways, the coronavirus disease 2019 (COVID-19) pandemic mirrors the challenges, lessons and opportunities of the HIV pandemic. In this article, we argue that global pandemics such as COVID-19 and HIV require a global response. We highlight the
Externí odkaz:
https://doaj.org/article/1ee1e956895f43a9a79a5cfa3b5aa9de
Autor:
Tamlyn A. Rautenberg, Shu Kay Ng, Gavin George, Mahomed-Yunus S. Moosa, Suzanne M. McCluskey, Rebecca F. Gilbert, Selvan Pillay, Isaac Aturinda, Kevin L. Ard, Winnie Muyindike, Nicholas Musinguzi, Godfrey Masette, Melendhran Pillay, Pravi Moodley, Jaysingh Brijkumar, Rajesh T. Gandhi, Brent Johnson, Henry Sunpath, Mwebesa B. Bwana, Vincent C. Marconi, Mark J. Siedner
Publikováno v:
Value in Health Regional Issues. 35:42-47
Autor:
P. Nathan Enick, Joseph P. Brooker, Camille M. Tumiotto, Brittany T. Staines, Joseph J. Eron, Deborah K. McMahon, Rajesh T. Gandhi, John W. Mellors, Michele D. Sobolewski
Publikováno v:
Journal of Virus Eradication, Vol 7, Iss 2, Pp 100043- (2021)
The quantitative viral outgrowth assay (qVOA) is the gold standard for measuring inducible, replication-competent HIV-1. Using MOLT4-R5 and SupT1-R5 cell lines instead of allogeneic blasts and HIV-1 RNA detection rather than p24 enzyme-immunoassay (E
Externí odkaz:
https://doaj.org/article/e18876d0e0a345828a73d0821fe4f652
Autor:
Kathleen W. Miller, Rajesh T. Gandhi
Publikováno v:
Current Opinion in HIV and AIDS. 18:119-125
Autor:
Eva M. Stevenson, Adam R. Ward, Ronald Truong, Allison S. Thomas, Szu-Han Huang, Thomas R. Dilling, Sandra Terry, John K. Bui, Talia M. Mota, Ali Danesh, Guinevere Q. Lee, Andrea Gramatica, Pragya Khadka, Winiffer D. Conce Alberto, Rajesh T. Gandhi, Deborah K. McMahon, Christina M. Lalama, Ronald J. Bosch, Bernard Macatangay, Joshua C. Cyktor, Joseph J. Eron, John W. Mellors, R. Brad Jones, for the AIDS Clinical Trials Group A5321 Team
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Antiretroviral therapies (ARTs) abrogate HIV replication; however, infection persists as long-lived reservoirs of infected cells with integrated proviruses, which reseed replication if ART is interrupted. A central tenet of our current understanding
Externí odkaz:
https://doaj.org/article/fb50f24e6e51492997ce0b7e07385aef
Autor:
You Park, Behzad Etemad, Hayat Ahmed, Vivek Naranbhai, Evgenia Aga, Ronald J. Bosch, John W. Mellors, Daniel R. Kuritzkes, Michael Para, Rajesh T. Gandhi, Mary Carrington, Jonathan Z. Li
Publikováno v:
Pathogens and Immunity, Vol 2, Iss 3, Pp 431-445 (2017)
Identifying host determinants associated with HIV reservoir size and viral rebound timing after an analytic treatment interruption (ATI) is an important step in the search for an HIV functional cure. A pooled analysis of 103 participants from four AI
Externí odkaz:
https://doaj.org/article/bc22cb7d3d5b4f56853590a96d3f654b