Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rajesh Subramaniam"'
Publikováno v:
International Surgery Journal. 8:3279
Background: Acute pancreatitis is an inflammatory disease of pancreas and is one of the leading cause of acute abdomen requiring hospital admission. Nutritional support plays a crucial role in this hypercatabolic state in not only providing calories
Publikováno v:
Organic Process Research & Development. 21:177-181
The acetylated headgroup of the most abundant mammalian phospholipid, 1,2-diacetyl-3-sn-phosphatidyl choline (DAcPC), has several important applications in research. For instance, it can be dissolved in the same amount of water as in the fluid PC bil
Publikováno v:
Langmuir
The headgroup (H) stratum (sometimes called the polar region) of membrane bilayers is a relevant yet poorly understood solvation phase for small molecules and macromolecules interacting with the membranes. Solvation of compounds in bilayer strata is
Publikováno v:
International Surgery Journal. :2351-2354
Polycythemia is an unusual manifestation of acute pancreatitis. When polycythemia does occur, it is almost invariably due to intravascular fluid depletion, contraction of Plasma volume, Gaisbock’s Syndrome, Primary congenital and familial polycythe
Publikováno v:
International Surgery Journal. :2343-2346
Eumycetoma is an uncommon infection in adults, especially as a co-infection with extra pulmonary tuberculosis. We report a unique case of Co-existence of Eumycetoma and tuberculosis in a same lesion in an adult from a known endemic area of Tamilnadu,
Autor:
Sandra Lynch, Rajesh Subramaniam, Senthil Natesan, Roman Tandlich, Viera Lukacova, Stefan Balaz, Zhanbin Wang, Ming Peng
Publikováno v:
Molecular Pharmaceutics
Solvation of drugs in the core (C) and headgroup (H) strata of phospholipid bilayers affects their physiological transport rates and accumulation. These characteristics, especially a complete drug distribution profile across the bilayer strata, are t
Autor:
Vladimir Bartus, Rajesh Subramaniam, Tiansheng Wang, Senthil Natesan, Stefan Balaz, Viera Lukacova, Akash Khandelwal
Publikováno v:
Journal of Medicinal Chemistry
We present the cellular quantitative structure–activity relationship (cell-QSAR) concept that adapts ligand-based and receptor-based 3D-QSAR methods for use with cell-level activities. The unknown intracellular drug disposition is accounted for by
Publikováno v:
Journal of Medicinal Chemistry
Treatment of ionization and tautomerism of ligands and receptors is one of the unresolved issues in structure-based prediction of binding affinities. Our solution utilizes the thermodynamic master equation, expressing the experimentally observed asso
Publikováno v:
Tetrahedron Letters. 51:529-532
Syntheses of coumarin-containing lipids and liposomal formulations incorporating these lipids are studied. The influence of the lipid head groups in enhancing the release efficiency of these liposomes under light irradiation is studied and a molecula
Publikováno v:
Tetrahedron. 59:10575-10580
Radical additions to oxazolidinone acrylate followed by allyl trapping were studied with chiral Lewis acids derived from lanthanide salts. Chiral ligands were evaluated to establish the α-stereocenter. Ligands with a prolinol framework along with ac