Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Rajesh Sonti"'
Autor:
Shweta Dhannura, Shamasoddin Shekh, Pooja Dhurjad, Ashwini Dolle, Sreepriya Kakkat, Vishwajyothi, Marimuthu Vijayasarathy, Rajesh Sonti, Konkallu Hanumae Gowd
Publikováno v:
ACS Omega, Vol 9, Iss 36, Pp 37596-37609 (2024)
Externí odkaz:
https://doaj.org/article/02bb5f60698741538f79e22e629bfa89
Autor:
Johannes Paladini, Annalena Maier, Judith Maria Habazettl, Ines Hertel, Rajesh Sonti, Stephan Grzesiek
Publikováno v:
eLife, Vol 12 (2024)
Abelson tyrosine kinase (Abl) is regulated by the arrangement of its regulatory core, consisting sequentially of the SH3, SH2, and kinase (KD) domains, where an assembled or disassembled core corresponds to low or high kinase activity, respectively.
Externí odkaz:
https://doaj.org/article/ef746d7d048644ea99ceb28b7e3f3eec
Publikováno v:
Metabolites, Vol 11, Iss 1, p 50 (2021)
Glucose is a major energy fuel for the brain, however, less is known about specificities of its metabolism in distinct cerebral areas. Here we examined the regional differences in glucose utilization between the hypothalamus and hippocampus using in
Externí odkaz:
https://doaj.org/article/e5ce80061f2a46d1bbba7b9505dd113e
Autor:
Siva Nageswara Rao Gajula, Ankita Sahebrao Khairnar, Pallavi Jock, Nikita Kumari, Kendre Pratima, Vijay Munjal, Pavan Kalan, Rajesh Sonti
Publikováno v:
Expert Review of Proteomics. 20:5-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f64cf09e882a2456c5ff3c882ae087e
https://doi.org/10.1080/14789450.2023.2191845
https://doi.org/10.1080/14789450.2023.2191845
Autor:
Priyanka N. Makhal, Srinivas Reddy Dannarm, Arbaz Sujat Shaikh, Rezwan Ahmed, Shrilekha Chilvery, Lahu N. Dayare, Rajesh Sonti, Chandraiah Godugu, Venkata Rao Kaki
Publikováno v:
Chemical Communications. 59:3767-3770
Woollins’ reagent was used for the synthesis of novel 2,5-disubstituted selenazolines with excellent regio- and chemoselectivity that show potential antiproliferative activity, paving the way for developing selenazoline-based anticancer agents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cab1a65cf0989a9ae7d0fc98bb0b91b
https://doi.org/10.1039/d2cc06782j
https://doi.org/10.1039/d2cc06782j
Publikováno v:
Chirality. 34:1419-1436
Stereoselective chiral molecules are responsible for specific biological functions in nature. At present, more than half of the prescribed drugs are chiral. Living organisms display divergent pharmacological responses to the enantiomers, leading to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00fe151582f661420504b0ff5d2cfa8
https://doi.org/10.1002/chir.23499
https://doi.org/10.1002/chir.23499
Autor:
Manoj P. Dandekar, Mani Surya Kumar Palepu, Srilakshmi Satti, Yash Jaiswal, Aditya A. Singh, Surya Prakash Dash, Siva Nageswara Rao Gajula, Rajesh Sonti
Publikováno v:
ACS Chemical Neuroscience. 13:1948-1965
Depression is a debilitating mental disorder that affects322 million people worldwide. Despite the availability of several antidepressant agents, many patients remain treatment refractory. A growing literature study has indicated the role of gut micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39510feaef8d97a6265306aa2b96ce43
https://doi.org/10.1021/acschemneuro.2c00143
https://doi.org/10.1021/acschemneuro.2c00143
Autor:
Siva Nageswara Rao Gajula, Sasikala Talari, Tanaaz Navin Nathani, Vijay Munjal, Ziaur Rahman, Manoj P Dandekar, Rajesh Sonti
Publikováno v:
Bioanalysis.
Aim: This study investigated the impact of food intake and circadian rhythms on the pharmacokinetics of mavacamten. Materials & methods: A sensitive bioanalytical method for quantifying mavacamten in rat plasma was developed and validated. This metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::642fb93402e4eb12d745805cd2dcf075
https://doi.org/10.4155/bio-2023-0030
https://doi.org/10.4155/bio-2023-0030
Autor:
Siva Nageswara Rao Gajula, Sasikala Talari, Shrilekha Chilvery, Godugu Chandraiah, Rajesh Sonti
Publikováno v:
RPS Pharmacy and Pharmacology Reports.
Objectives Garcinol exhibits promising potential anticancer activity in cancer cells by inhibiting several critical regulatory pathways. Despite its pharmacological activities, information regarding its pharmacokinetics and metabolism is unavailable.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a9b3960d5122fa71a61f46633c68a3f
https://doi.org/10.1093/rpsppr/rqad017
https://doi.org/10.1093/rpsppr/rqad017
Autor:
Manasa Purushotham, Bishwajit Paul, Siva Nageswara Rao Gajula, Biswajit Sahariah, Rajesh Sonti
Publikováno v:
New Journal of Chemistry. 46:19648-19657
We deciphered weak interactions in aromatic peptoids, such as C–H⋯O/X, and simultaneously identified strong interactions, including N–H⋯N and N–H⋯O, in this class of foldamer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18a8019798725415eb331d7ea5694178
https://doi.org/10.1039/d2nj02616c
https://doi.org/10.1039/d2nj02616c