Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Rajesh Somasundaram"'
Autor:
Christina T. Jensen, Josefine Åhsberg, Johanna Tingvall-Gustafsson, Rajesh Somasundaram, Stefan Lang, Jonas Ungerbäck, Anna Porwit, Shamit Soneji, Mikael Sigvardsson
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/1824c25cb8e9403ba9943e8c2d767111
Autor:
Josefine Åhsberg, Pingnan Xiao, Kazuki Okuyama, Rajesh Somasundaram, Tobias Strid, Hong Qian, Mikael Sigvardsson
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/6844f3330f55450b93fd93d849186633
Autor:
Kazuki Okuyama, Tobias Strid, Jacob Kuruvilla, Rajesh Somasundaram, Susana Cristobal, Emma Smith, Mahadesh Prasad, Thoas Fioretos, Henrik Lilljebjörn, Shamit Soneji, Stefan Lang, Jonas Ungerbäck, Mikael Sigvardsson
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008280 (2019)
One of the most frequently mutated proteins in human B-lineage leukemia is the transcription factor PAX5. These mutations often result in partial rather than complete loss of function of the transcription factor. While the functional dose of PAX5 has
Externí odkaz:
https://doaj.org/article/5fcac02b5c7e4662a7aaef4e9b59c486
Autor:
Rajesh Somasundaram, Sandra Fernandes, Jasper J Deuring, Colin de Haar, Ernst J Kuipers, Lauran Vogelaar, Frank A Middleton, C Janneke van der Woude, Maikel P Peppelenbosch, William G Kerr, Gwenny M Fuhler
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182308 (2017)
SH2 domain containing inositol-5-phosphatase (SHIP1) is an important modulator of innate and adaptive immunity. In mice, loss of SHIP1 provokes severe ileitis resembling Crohn's disease (CD), as a result of deregulated immune responses, altered cytok
Externí odkaz:
https://doaj.org/article/438601c795fd434ca47b09f3b310e90a
Autor:
Rajesh Somasundaram, Veerle J A A Nuij, C Janneke van der Woude, Ernst J Kuipers, Maikel P Peppelenbosch, Gwenny M Fuhler
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84521 (2013)
The role of the innate immunity in the pathogenesis of Crohn's disease (CD), an inflammatory bowel disease, is a subject of increasing interest. Neutrophils (PMN) are key members of the innate immune system which migrate to sites of bacterial infecti
Externí odkaz:
https://doaj.org/article/8b07e07528a34ca5bc894ae13167c671
Autor:
Saravanan Yuvaraj, Sa’ad H. Al-Lahham, Rajesh Somasundaram, Patrick A. Figaroa, Maikel P. Peppelenbosch, Nicolaas A. Bos
Publikováno v:
Gastroenterology Research and Practice, Vol 2012 (2012)
Colon cancer is a serious health problem, and novel preventive and therapeutical avenues are urgently called for. Delivery of proteins with anticancer activity through genetically modified bacteria provides an interesting, potentially specific, econo
Externí odkaz:
https://doaj.org/article/5c3a035ef2a44593b1050c19517e233f
Autor:
Christina T Jensen, Josefine Åhsberg, Johanna Tingvall-Gustafsson, Rajesh Somasundaram, Stefan Lang, Jonas Ungerbäck, Anna Porwit, Shamit Soneji, Mikael Sigvardsson
Publikováno v:
Haematologica.
Not available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b05cb5bd1e75efe7caf244e8aba629d
https://doi.org/10.3324/haematol.2022.282430
https://doi.org/10.3324/haematol.2022.282430
Autor:
Mahadesh A J Prasad, Xun Wang, Mikael Sigvardsson, Kazuki Okuyama, Tobias Strid, Christina Jensen, James Hagman, Josefine Åhsberg, Rajesh Somasundaram, Shamit Soneji, Johanna Tingvall-Gustafsson, Jonas Ungerbäck
Publikováno v:
Blood
Genes encoding B lineage–restricted transcription factors are frequently mutated in B-lymphoid leukemias, suggesting a close link between normal and malignant B-cell development. One of these transcription factors is early B-cell factor 1 (EBF1), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eea76900ff4e9fb1545bf3fc324fd0e
https://europepmc.org/articles/PMC8176764/
https://europepmc.org/articles/PMC8176764/
Autor:
Christina Jensen, Johanna Tingvall-Gustafsson, Mikael Sigvardsson, Tobias Strid, Susana Cristobal, Jacob Kuruvilla, Jonas Ungerbäck, Rajesh Somasundaram, Kazuki Okuyama, Josefine Åhsberg, Mahadesh A J Prasad, Stefan Lang, Shamit Soneji
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 206(11)
B lymphocyte development is dependent on the interplay between the chromatin landscape and lineage-specific transcription factors. It has been suggested that B lineage commitment is associated with major changes in the nuclear chromatin environment,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f8092ada76abcb4c80ac036c7b070c
https://pubmed.ncbi.nlm.nih.gov/34021049
https://pubmed.ncbi.nlm.nih.gov/34021049
Autor:
Audrey Astori, Mikael Sigvardsson, Tobias Strid, Maria Sunnerhagen, Jacob Kuruvilla, Rajesh Somasundaram, Brian Raught, Jonas Ungerbäck, Johanna Tingvall-Gustafsson, Estelle M.N. Laurent, Josefine Åhsberg, Etienne Coyaud
Publikováno v:
Journal of Immunology
Journal of Immunology, 2020, Journal of immunology (Baltimore, Md. 1950), 205 (5), pp.1419-1432. ⟨10.4049/jimmunol.1900959⟩
Journal of Immunology, 2020, Journal of immunology (Baltimore, Md. 1950), 205 (5), pp.1419-1432. ⟨10.4049/jimmunol.1900959⟩
Maturation of lymphoid cells is controlled by the action of stage and lineage-restricted transcription factors working in concert with the general transcription and chromatin remodeling machinery to regulate gene expression. To better understand this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f560d9340dd8a8c768145b3963c573b9
http://hdl.handle.net/20.500.12210/75016
http://hdl.handle.net/20.500.12210/75016