Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Rajesh N. Davé"'
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2305 (2022)
The robustness of 3D-printed mini-tablets as a platform to administer milligram dosages, intended for age-specific therapy, without the need of tablet splitting while maintaining similar release profiles, was investigated. Griseofulvin, as a model po
Externí odkaz:
https://doaj.org/article/2b72fd62e6344598846f782bb8aaa652
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1857 (2021)
Filaments loaded with griseofulvin (GF), a model poorly water-soluble drug, were prepared and used for 3D printing via fused deposition modeling (FDM). GF was selected due to its high melting temperature, enabling lower temperature hot-melt extrusion
Externí odkaz:
https://doaj.org/article/5a8bf4a5b9e844099a534933b982c644
Autor:
Guluzar G. Buyukgoz, Jeremiah N. Castro, Andrew E. Atalla, John G. Pentangelo, Siddharth Tripathi, Rajesh N. Davé
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 812 (2021)
The impact of mixer type and critical process parameters (CPPs) on critical quality attributes (CQAs), including the drug content uniformity (CU) of slurry-cast polymer films loaded with micro-sized poorly water-soluble drugs were investigated. Previ
Externí odkaz:
https://doaj.org/article/d62d119545e542a9a566aacde4782ff2
Publikováno v:
Pharmaceuticals, Vol 12, Iss 3, p 109 (2019)
Hydrophobic drug nanocrystals (NCs) manufactured by particle engineering have been extensively investigated for enhanced oral bioavailability and therapeutic effectiveness. However, there are significant drawbacks, including fast dissolution of the n
Externí odkaz:
https://doaj.org/article/59455755ec8f40faaad6a16ace7c84b0
Autor:
Changquan Calvin Sun, Rajesh N. Davé
Publikováno v:
Pharmaceutical Research. 39:3041-3045
Publikováno v:
Pharmaceutical Research. 39:3079-3098
Fine API agglomeration and its mitigation via particle engineering, i.e., dry coating, remains underexplored. The purpose was to investigate agglomeration before and after dry coating of fine cohesive APIs and impact on powder processability, i.e., f
Publikováno v:
AAPS PharmSciTech. 24
Autor:
Tyler J, DiStefano, Keti, Vaso, Christopher J, Panebianco, George, Danias, Henry N, Chionuma, Kuriakose, Kunnath, Stylianos Z, Karoulias, Minghui, Wang, Peng, Xu, Rajesh N, Davé, Susmita, Sahoo, Jennifer R, Weiser, James C, Iatridis
Publikováno v:
Cartilage. 13(3)
Intervertebral disk degeneration is a prevalent postoperative complication after discectomy, underscoring the need to develop preventative and bioactive treatment strategies that decelerate degeneration and seal annulus fibrosus (AF) defects. Human m
Publikováno v:
Pharmaceutical research. 39(12)
The impact of dry coating on reduced API agglomeration remains underexplored. Therefore, this work quantified fine cohesive API agglomeration reduction through dry coating and its impact on enhanced blend uniformity and processability, i.e., flowabil
Publikováno v:
AIChE Journal. 68