Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Rajesh N, Gacche"'
Autor:
Snehal Nimal, Navanath Kumbhar, Saruchi, Shriya Rathore, Nitin Naik, Sneha Paymal, Rajesh N. Gacche
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-28 (2024)
Abstract Triple-negative breast cancer (TNBC) is a metastatic disease and a formidable treatment challenge as it does not respond to existing therapies. Epigenetic regulators play a crucial role in the progression and metastasis by modulating the exp
Externí odkaz:
https://doaj.org/article/38465e5bc7a747ea90c1cd9124417f39
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35369- (2024)
Metastasis is an intricate and formidable pathophysiological process encompassing the dissemination of cancer cells from the primary tumour body to distant organs. It stands as a profound and devastating phenomenon that constitutes the primary driver
Externí odkaz:
https://doaj.org/article/29c1a59782904fb0908d11d6c22a4f11
Autor:
Navanath Kumbhar, Snehal Nimal, Deeksha Patil, V. Florian Kaiser, Joachim Haupt, Rajesh N. Gacche
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Modifications in the epigenetic landscape have been considered a hallmark of cancer. Histone deacetylation is one of the crucial epigenetic modulations associated with the aggressive progression of various cancer subtypes. Herein, we have re
Externí odkaz:
https://doaj.org/article/d30a122d007746ee883e12ba03a031d8
Autor:
Pinaki Banerjee, Prachi Kapse, Shehnaz Siddique, Moumita Kundu, Jasoda Choudhari, Varshasnata Mohanty, Diksha Malhotra, Suresh W. Gosavi, Rajesh N. Gacche, Gopal C. Kundu
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 6, Pp 401-420 (2023)
Prostate cancer, one of the most frequently occurring cancers in men, is a heterogeneous disease involving multiple cell types within tumors. This tumor heterogeneity at least partly results from genomic instability leading to sub-clonal cellular dif
Externí odkaz:
https://doaj.org/article/df3d513445a041d7bdc50cd12c45cca0
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22591- (2023)
Non-small cell lung cancer (NSCLC) is one of the most devastating cancers with a high incidence and mortality rates of all cancers. Locally advanced or metastatic NSCLC patients can benefit from platinum-based chemotherapy and targeted therapy drugs.
Externí odkaz:
https://doaj.org/article/ae10b2f20e7248c881dab812a9d1d98a
Autor:
Sonali S. Kamble, Jasoda Choudhari, Ramakrishna Nimma, Totakura Venkata Santosh Kumar, Kapil K. Patil, Shrikant V. Hese, Bhaskar S. Dawane, Rajesh N. Gacche
Publikováno v:
Cancer Reports, Vol 5, Iss 10, Pp n/a-n/a (2022)
Abstract Background Natural products with targeted bioactivity have gained major attention in the field of cancer research owing to emerging anti‐cancer drug resistance and off target toxicities. Chloroxylon swietenia (Roxb.) DC is recognized as a
Externí odkaz:
https://doaj.org/article/e2d00c2f9c2e467f83e11d7f3daef3cc
Autor:
Madhav J. Hebade, Sambhaji T. Dhumal, Sonali S. Kamble, Tejshri R. Deshmukh, Vijay M. Khedkar, Shrikant V. Hese, Rajesh N. Gacche, Bhaskar S. Dawane
Publikováno v:
Polycyclic Aromatic Compounds. 43:2866-2887
A series of new substituted benzimidazole-thiazoles (9a–l) have been designed and synthesized using 2-aminothiazole as a starting material by using molecular hybridization approach. The newly synthesized compounds were characterized by 1H NMR, 13C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff44a5331673e0e301139bb41a4d59e2
https://doi.org/10.1080/10406638.2022.2056210
https://doi.org/10.1080/10406638.2022.2056210
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 6, Iss 4, Pp 355-361 (2016)
The present study was carried out to evaluate in vivo and in vitro anti-inflammatory potential of selected medicinal plants used in Indian traditional medication. The sequentially extracted plant samples as, Cissus quadrangularis, Plumbago zeylanica,
Externí odkaz:
https://doaj.org/article/6bcc54f456eb47a08c0f08933b36c2dd
Autor:
Jasoda Choudhari, Ramakrishna Nimma, Snehal K. Nimal, Santosh Kumar Totakura Venkata, Gopal C. Kundu, Rajesh N. Gacche
Publikováno v:
Journal of Ethnopharmacology. 312:116472
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d870935c151b73339c4bcdc342cf9bf8
https://doi.org/10.1016/j.jep.2023.116472
https://doi.org/10.1016/j.jep.2023.116472
Publikováno v:
Journal of Herbs, Spices & Medicinal Plants. 27:343-364
The antioxidant potential (% RSA and EC50) of solvent extracts of leaves and roots of Lobelia nicotianifolia Roth. was assessed using five in vitro assays. The EC50 values of methanolic extract wer...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7e6aea9ee846b3689d3c95241769ec
https://doi.org/10.1080/10496475.2021.1932006
https://doi.org/10.1080/10496475.2021.1932006