Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rajesh Kumar Manne"'
Autor:
Ganesh Kumar Barik, Osheen Sahay, Anindya Mukhopadhyay, Rajesh Kumar Manne, Sehbanul Islam, Anup Roy, Somsubhra Nath, Manas Kumar Santra
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-15 (2023)
Abstract Oncogene Moesin plays critical role in initiation, progression, and metastasis of multiple cancers. It exerts oncogenic activity due to its high-level expression as well as posttranslational modification in cancer. However, factors responsib
Externí odkaz:
https://doaj.org/article/b75e6049643f48a992d2e7b50b2ae701
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-17 (2022)
Abstract Growth factor signaling plays a pivotal role in diverse biological functions, such as cell growth, apoptosis, senescence, and migration and its deregulation has been linked to various human diseases. Akt kinase is a central player transmitti
Externí odkaz:
https://doaj.org/article/bc9f92b054754c75b6d54ecc2ddc4f20
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101940- (2023)
Summary: Here, we present optimized approaches to identify the efficiency of cancer cell phagocytosis by macrophages in vitro and in vivo. We describe the preparation and co-culture of macrophages and cancer cells, followed by in vitro phagocytosis a
Externí odkaz:
https://doaj.org/article/cd48d86fd8b84880b9210c98ad7fe34b
Autor:
Chuan Xu, Guoxiang Jin, Hong Wu, Wei Cui, Yu-Hui Wang, Rajesh Kumar Manne, Guihua Wang, Weina Zhang, Xian Zhang, Fei Han, Zhen Cai, Bo-Syong Pan, Che-Chia Hsu, Yiqiang Liu, Anmei Zhang, Jie Long, Hongbo Zou, Shuang Wang, Xiaodan Ma, Jinling Duan, Bin Wang, Weihui Liu, Haitao Lan, Qing Xiong, Gang Xue, Zhongzhu Chen, Zhigang Xu, Mark E. Furth, Sarah Haigh Molina, Yong Lu, Dan Xie, Xiu-Wu Bian, Hui-Kuan Lin
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Cancer stem-like cells (CSLCs) acquire enhanced immune checkpoint responses to evade immune cell killing and promote tumor progression. Here we showed that signal regulatory protein γ (SIRPγ) determined CSLC properties and immune evasiveness in a s
Externí odkaz:
https://doaj.org/article/ed9d232ee19b4520b69e25795aaa76fb
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/53cb06a276e94364a428b20bb723365e
Autor:
Rajesh Kumar Manne, Yashika Agrawal, Anil Bargale, Asha Patel, Debasish Paul, Neha Anilkumar Gupta, Srikanth Rapole, Vasudevan Seshadri, Deepa Subramanyam, Praveenkumar Shetty, Manas Kumar Santra
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 6, Pp 483-495 (2017)
The transformation of a normal cell to cancer requires the derail of multiple pathways. Normal signaling in a cell is regulated at multiple stages by the presence of feedback loops, calibration of levels of proteins by their regulated turnover, and p
Externí odkaz:
https://doaj.org/article/59eeeb538db6432a893b33f9a2130b06
Autor:
Rajni Kant, Rajesh Kumar Manne, Mohammad Anas, Vasudevarao Penugurti, Tingjin Chen, Bo-Syong Pan, Che-Chia Hsu, Hui-Kuan Lin
Publikováno v:
Seminars in cancer biology. 86(Pt 3)
Metabolic reprogramming is an important cancer hallmark that plays a key role in cancer malignancies and therapy resistance. Cancer cells reprogram the metabolic pathways to generate not only energy and building blocks but also produce numerous key s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd4aa98296d4b3739b63fcb70a52974
https://pubmed.ncbi.nlm.nih.gov/36244530
https://pubmed.ncbi.nlm.nih.gov/36244530
Autor:
Bo-Syong Pan, Rajesh Kumar Manne, Che-Chia Hsu, Zhen Cai, Danni Peng, Asad Moten, Hong-yu Li, Hui Kuan Lin
Publikováno v:
Semin Cancer Biol
Strictly regulated protein degradation by ubiquitin-proteasome system (UPS) is essential for various cellular processes whose dysregulation is linked to serious diseases including cancer. Skp2, a well characterized component of Skp2-SCF E3 ligase com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026486f8b7ea4c11e3febb3375fcbec9
https://doi.org/10.1016/j.semcancer.2020.01.013
https://doi.org/10.1016/j.semcancer.2020.01.013
Publikováno v:
Toxicology and applied pharmacology. 441
Arsenic trioxide (ATO), a potent anti-neoplastic drug, is known to prevent cancer cell growth through induction of autophagic cell death. However, importance of cellular factors in ATO-mediated autophagic cell death is poorly understood. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161f7930cfe449dc3e1c9b0c8fdbcbaa
https://pubmed.ncbi.nlm.nih.gov/35278439
https://pubmed.ncbi.nlm.nih.gov/35278439
Autor:
Xian Zhang, Weina Zhang, Amit Ketkar, Chuan Xu, Zhong-Zhu Chen, Emily Lin, Guoxiang Jin, Hong-yu Li, Che-Chia Hsu, Zhen Cai, Zhi-Gang Xu, Haiwei Gu, Tingjin Chen, Bo-Syong Pan, Hui Kuan Lin, Yan Jin, Robert L. Eoff, Xiangshang Xu, Guihua Wang, Rajesh Kumar Manne, Wei Yan, Jing-Wei Shao
Publikováno v:
Mol Cell
Mitochondrial dynamics regulated by mitochondrial fusion and fission maintain mitochondrial functions, whose alterations underline various human diseases. Here, we show that inositol is a critical metabolite directly restricting AMPK-dependent mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855ebc5de6492ed6dca554257701c386
https://europepmc.org/articles/PMC8462099/
https://europepmc.org/articles/PMC8462099/
