Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rajesh Kumar Gandhi"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 5, Pp 333-349 (2014)
Lipid-based formulations have been an attractive choice among novel drug delivery systems for enhancing the solubility and bioavailability of poorly soluble drugs due to their ability to keep the drug in solubilized state in the gastrointestinal trac
Externí odkaz:
https://doaj.org/article/4a2d94b5ea3340b6b8ca2928d9ad1ebf
Autor:
Roopak Murali, Rachel Evangelina, Joanna Pauline Samuel, Pooja Singh, Shivangi Saha, Maneesh Singhal, Rajesh Kumar Gandhirajan
Publikováno v:
Redox Experimental Medicine, Vol 2024, Iss 1, Pp 1-18 (2024)
Chronic wounds take longer to heal and, if left untreated, can result in severe repercussions such as sepsis, gangrene, and amputation. The current treatment procedures followed are wound cleaning and debridement, specialized dressings, antibiotics a
Externí odkaz:
https://doaj.org/article/27c7a252072f44ad94356f78df85ff2d
Autor:
Sneha S. Patil, Naveen Puttaswamy, Sachin C. Sarode, Gargi S. Sarode, Smita S. Patil, Andres Cardenas, Rajesh Kumar Gandhirajan, Kalpana Balakrishnan
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Exposure to environmental tobacco smoke (ETS) is arguably the most ubiquitous and hazardous, even at very low levels, starting in early life. The objective of this study was to describe the state of research and future trends on E
Externí odkaz:
https://doaj.org/article/83e0a174afab433688f47049e85c34d1
Autor:
Roopak Murali, Vaishnavi Balasubramaniam, Satish Srinivas, Sandhya Sundaram, Ganesh Venkatraman, Sudha Warrier, Arun Dharmarajan, Rajesh Kumar Gandhirajan
Publikováno v:
Metabolites, Vol 13, Iss 4, p 560 (2023)
Ovarian cancers are tumors that originate from the different cells of the ovary and account for almost 4% of all the cancers in women globally. More than 30 types of tumors have been identified based on the cellular origins. Epithelial ovarian cancer
Externí odkaz:
https://doaj.org/article/fc4af6e332fd4b70ae83324d7f3f785a
Autor:
Sander Bekeschus, Sebastian Eisenmann, Sanjeev Kumar Sagwal, Yana Bodnar, Juliane Moritz, Broder Poschkamp, Ingo Stoffels, Steffen Emmert, Muniswamy Madesh, Klaus-Dieter Weltmann, Thomas von Woedtke, Rajesh Kumar Gandhirajan
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
Cold physical plasma is a partially ionized gas investigated as a new anticancer tool in selectively targeting cancer cells in monotherapy or in combination with therapeutic agents. Here, we investigated the intrinsic resistance mechanisms of tumor c
Externí odkaz:
https://doaj.org/article/39ea7e89b1774d2b8e120928104178c7
Autor:
Rajesh Kumar Gandhirajan, Katrin Rödder, Yana Bodnar, Gabriella Pasqual-Melo, Steffen Emmert, Corinne E. Griguer, Klaus-Dieter Weltmann, Sander Bekeschus
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Despite striking advances in the treatment of metastasized melanoma, the disease is often still fatal. Attention is therefore paid towards combinational regimens. Oxidants endogenously produced in mitochondria are currently targeted in pre-c
Externí odkaz:
https://doaj.org/article/e7765252a4bf4fd98c1c2fb12bede776
Autor:
Gabriella Pasqual-Melo, Sanjeev Kumar Sagwal, Eric Freund, Rajesh Kumar Gandhirajan, Benjamin Frey, Thomas von Woedtke, Udo Gaipl, Sander Bekeschus
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1379 (2020)
Despite continuous advances in therapy, malignant melanoma is still among the deadliest types of cancer. At the same time, owing to its high plasticity and immunogenicity, melanoma is regarded as a model tumor entity when testing new treatment approa
Externí odkaz:
https://doaj.org/article/a7f68d05cfd54b0388c69a635ebf2a08
Autor:
Nicholas E. Hoffman, Harish C. Chandramoorthy, Santhanam Shamugapriya, Xueqian Zhang, Sudarsan Rajan, Karthik Mallilankaraman, Rajesh Kumar Gandhirajan, Ronald J. Vagnozzi, Lucas M. Ferrer, Krishnalatha Sreekrishnanilayam, Kalimuthusamy Natarajaseenivasan, Sandhya Vallem, Thomas Force, Eric T. Choi, Joseph Y. Cheung, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1576-1588 (2013)
Resting mitochondrial matrix Ca2+ is maintained through a mitochondrial calcium uptake 1 (MICU1)-established threshold inhibition of mitochondrial calcium uniporter (MCU) activity. It is not known how MICU1 interacts with MCU to establish this Ca2+ t
Externí odkaz:
https://doaj.org/article/c0a8a3bb30744a0ab88b6a28b151800a
Publikováno v:
Antioxidants, Vol 7, Iss 11, p 151 (2018)
Increasing numbers of cancer deaths worldwide demand for new treatment avenues. Cold physical plasma is a partially ionized gas expelling a variety of reactive oxygen and nitrogen species, which can be harnesses therapeutically. Plasmas and plasma-tr
Externí odkaz:
https://doaj.org/article/387ba9c1615145e68abe42688afa2bfe
Autor:
Rajesh Kumar Gandhirajan, Peter Anton Staib, Katharina Minke, Iris Gehrke, Günther Plickert, Axel Schlösser, Esther Katharina Schmitt, Michael Hallek, Karl-Anton Kreuzer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 4, Pp 326-335 (2010)
BACKGROUND: Lymphoid enhancer factor-1 (lef-1) is overexpressed in B-cell chronic lymphocytic leukemia (CLL) when compared with normal B cells and transcribes several genes implicated in the pathogenesis of CLL. We therefore hypothesize that antagoni
Externí odkaz:
https://doaj.org/article/90182ad983b544c8b8187878433f3965