Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Rajesh Kumar, Soni"'
Autor:
Chuanjiang Yu, Qiong Shen, Antony B. Holmes, Tongwei Mo, Anna Tosato, Rajesh Kumar Soni, Clarissa Corinaldesi, Sanjay Koul, Laura Pasqualucci, Shafinaz Hussein, Farhad Forouhar, Riccardo Dalla-Favera, Katia Basso
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The myocyte enhancer factor 2B (MEF2B) transcription factor is frequently mutated in germinal center (GC)-derived B-cell lymphomas. Its ammino (N)-terminal mutations drive lymphomagenesis by escaping interaction with transcriptional represso
Externí odkaz:
https://doaj.org/article/6292144c17b347ab9eb2ceaf501c6457
Autor:
Monia Souidi, Jessica Resta, Haikel Dridi, Yvonne Sleiman, Steve Reiken, Karina Formoso, Sarah Colombani, Pascal Amédro, Pierre Meyer, Azzouz Charrabi, Marie Vincenti, Yang Liu, Rajesh Kumar Soni, Frank Lezoualc'h, D.V.M. Stéphane Blot, François Rivier, Olivier Cazorla, Angelo Parini, Andrew R. Marks, Jeanne Mialet‐Perez, Alain Lacampagne, Albano C. Meli
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 536-551 (2024)
Abstract Background Duchenne muscular dystrophy (DMD) is an X‐linked disorder characterized by progressive muscle weakness due to the absence of functional dystrophin. DMD patients also develop dilated cardiomyopathy (DCM). We have previously shown
Externí odkaz:
https://doaj.org/article/86cf946208c7405482fdfb4f8454571b
Autor:
Marcella E. O’Reilly, Sebastian Ho, Johana Coronel, Lucie Zhu, Wen Liu, Chenyi Xue, Eunyoung Kim, Esther Cynn, Caio V. Matias, Rajesh Kumar Soni, Chen Wang, Iuliana Ionita-Laza, Robert C. Bauer, Leila Ross, Yiying Zhang, Silvia Corvera, Susan K. Fried, Muredach P. Reilly
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114240- (2024)
Summary: Adipose tissue remodeling and dysfunction, characterized by elevated inflammation and insulin resistance, play a central role in obesity-related development of type 2 diabetes (T2D) and cardiovascular diseases. Long intergenic non-coding RNA
Externí odkaz:
https://doaj.org/article/577c9a29704b4b8ca143497013362bb5
Autor:
Rajesh Kumar Soni
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102381- (2023)
Summary: Formalin-fixed paraffin-embedded (FFPE) samples are valuable archived bio-specimens of individuals and are commonly used in biomedical research. Here, we present a protocol for deep proteomic profiling of FFPE specimens using a spectral libr
Externí odkaz:
https://doaj.org/article/4d36d3210bb445678cf6d0cdea0791cd
Autor:
Nicholas P. Giangreco, Guillaume Lebreton, Susan Restaino, Maryjane Farr, Emmanuel Zorn, Paolo C. Colombo, Jignesh Patel, Rajesh Kumar Soni, Pascal Leprince, Jon Kobashigawa, Nicholas P. Tatonetti, Barry M. Fine
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Heart transplantation remains the definitive treatment for end stage heart failure. Because availability is limited, risk stratification of candidates is crucial for optimizing both organ allocations and transplant outcomes. Here we utilize
Externí odkaz:
https://doaj.org/article/6446af2595e543f99511c9b5f7256dd6
Autor:
Jacinda Chen, Rajesh Kumar Soni, Yimeng Xu, Sabrina Simoes, Feng-Xia Liang, Laura DeFreitas, Robert Hwang, Jr., Jorge Montesinos, Joseph H. Lee, Estela Area-Gomez, Renu Nandakumar, Badri Vardarajan, Catherine Marquer
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104628- (2023)
Summary: Background: The most common form of neuronal ceroid lipofuscinosis (NCL) is juvenile CLN3 disease (JNCL), a currently incurable neurodegenerative disorder caused by mutations in the CLN3 gene. Based on our previous work and on the premise th
Externí odkaz:
https://doaj.org/article/7c799b4b21b24ad59d3201ed5f5b8cc6
Autor:
Josephine Y. Wu, Keith Yeager, Daniel Naveed Tavakol, Margaretha Morsink, Bryan Wang, Rajesh Kumar Soni, Clark T. Hung, Gordana Vunjak-Novakovic
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112509- (2023)
Summary: In tissue development and homeostasis, transforming growth factor (TGF)-β signaling is finely coordinated by latent forms and matrix sequestration. Optogenetics can offer precise and dynamic control of cell signaling. We report the developm
Externí odkaz:
https://doaj.org/article/72a66df3412044ab83c7f69655a5c54d
Autor:
Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, t
Externí odkaz:
https://doaj.org/article/fcc94ce778e043e9991e8da7d30777e4
Autor:
Ayelet M Rosenberg, Shannon Rausser, Junting Ren, Eugene V Mosharov, Gabriel Sturm, R Todd Ogden, Purvi Patel, Rajesh Kumar Soni, Clay Lacefield, Desmond J Tobin, Ralf Paus, Martin Picard
Publikováno v:
eLife, Vol 10 (2021)
Background: Hair greying is a hallmark of aging generally believed to be irreversible and linked to psychological stress. Methods: Here, we develop an approach to profile hair pigmentation patterns (HPPs) along individual human hair shafts, producing
Externí odkaz:
https://doaj.org/article/35d0dd96c5ff465ebd75a8acc8547e1f
Autor:
Aram Ko, Mohammad Hasanain, Young Taek Oh, Fulvio D'Angelo, Danika Sommer, Brulinda Frangaj, Suzanne Tran, Franck Bielle, Bianca Pollo, Rosina Paterra, Karima Mokhtari, Rajesh Kumar Soni, Matthieu Peyre, Marica Eoli, Laura Papi, Michel Kalamarides, Marc Sanson, Antonio Iavarone, Anna Lasorella
Publikováno v:
Cancer Discovery. 13:702-723
LZTR1 is the substrate-specific adaptor of a CUL3-dependent ubiquitin ligase frequently mutated in sporadic and syndromic cancer. We combined biochemical and genetic studies to identify LZTR1 substrates and interrogated their tumor-driving function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6239b16e0f2ba85ffa82f2f163c00d3b
https://doi.org/10.1158/2159-8290.cd-22-0376
https://doi.org/10.1158/2159-8290.cd-22-0376