Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rajesh Krithika"'
Autor:
Rajesh Krithika, Ramtej Jayaram Verma
Publikováno v:
Clinical Phytoscience, Vol 5, Iss 1, Pp 1-8 (2019)
Abstract Background Hepatotoxicity induced by carbon tetrachloride (CCl4) is used as an experimental model to screen phytochemicals with liver protecting activity. Solanum nigrum (SN) is a shrub which is widely distributed throughout India. Tradition
Externí odkaz:
https://doaj.org/article/ab8e9afa9d8944308ce89ad3eca0e7d7
Publikováno v:
Journal of Drug Delivery Science and Technology. 51:364-371
Phyllanthin is a well-known hepatoprotective lignin from the plant Phyllanthus amarus (P. amarus). Its limited solubility in water makes is suitable candidate for nanoparticulate drug delivery system which can provide benefits of better absorption as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b89564b5269a7a44ad802bda2ec55dc
https://doi.org/10.1016/j.jddst.2019.03.019
https://doi.org/10.1016/j.jddst.2019.03.019
Autor:
Rajesh Krithika, Ramtej Jayaram Verma
Publikováno v:
Toxicology and Environmental Health Sciences. 10:268-277
Carbon tetrachloride (CCl4) toxicity is the model commonly exploited to produce hepatic damage. This model is used to screen drugs with hepatoprotective activity on various experimental animals and to validate their liver protecting property. Carbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c9a1f5b33f77ac712f8fe41de005b22
https://doi.org/10.1007/s13530-018-0375-z
https://doi.org/10.1007/s13530-018-0375-z
Publikováno v:
Toxicology and Industrial Health. 32:953-960
Hepatic fibrosis is an important outcome of chronic liver injury and results in excess synthesis and accumulation of extracellular matrix (ECM) components. Phyllanthin (PLN) isolated from Phyllanthus amarus exhibits strong antioxidative property and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9b1861a214d1c27e367f38845289d6
https://doi.org/10.1177/0748233714532996
https://doi.org/10.1177/0748233714532996
Ameliorative effects of phyllanthin on carbon tetrachloride-induced hepatic oxidative damage in mice
Autor:
Ramtej Jayaram Verma, Rajesh Krithika
Publikováno v:
Asian Pacific Journal of Tropical Disease, Vol 4, Iss Sup 1, Pp 64-70 (2014)
Objective To evaluate the liver protecting efficacy of phyllanthin, a lignin, isolated from the leaves of Phyllanthus amarus using mice model. Methods Phyllanthin was orally administered with or without CCl 4 for 30 d. Serum levels of hepatic marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4b89bed77bba498e05e32a8a833d70
http://oaji.net/articles/2016/3556-1469494421.pdf
http://oaji.net/articles/2016/3556-1469494421.pdf
Publikováno v:
Journal of Clinical and Experimental Hepatology. 3:29-36
Aflatoxins are a group of mycotoxins produced by Aspergillus flavus and Aspergillus parasiticus and are potent inducers of hepatotoxicity.The present study was carried out to investigate the effect of black tea infusion on aflatoxin-induced hepatotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ab4b3ec6814034d9aa5d06c7fbd658
https://doi.org/10.1016/j.jceh.2012.12.003
https://doi.org/10.1016/j.jceh.2012.12.003
Publikováno v:
Human & Experimental Toxicology. 32:530-543
This article describes antioxidative and cytoprotective property of andrographolide, a major active component of the plant Andrographis paniculata ( A. paniculata). High yields (2.7%) of andrographolide was isolated from the aerial parts of this plan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1942b14220a9eb2db5eb5f541d8fe6ca
https://doi.org/10.1177/0960327112459530
https://doi.org/10.1177/0960327112459530
Publikováno v:
Toxicology mechanisms and methods. 25(9)
Chronic injury to liver triggers synthesis of extracellular matrix components resulting in progressive fibrosis and eventually cirrhosis. Transforming growth factor-β1 (TGF-β1) transduces its signal by binding to TGF-β type 1 receptor kinase or ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4439cb0ba9c4c514dea37dad83d75030
https://pubmed.ncbi.nlm.nih.gov/28443691
https://pubmed.ncbi.nlm.nih.gov/28443691
Autor:
Lonchin Suguna, Rajesh Krithika, Moorthy Ganeshkumar, Thangavel Ponrasu, Vinaya Subramani Gayathri, Kuttalam Iyappan
Publikováno v:
Journal of ethnopharmacology. 142(1)
Ethnopharmacological relevance Acalypha indica Linn. (Acalypha indica) vernacularly called Kuppaimeni in Tamil, has been used as a folklore medicine since ages for the treatment of wounds by tribal people of Tamil Nadu, Southern India. The present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168df99fa2136f5fcb20b52704da9a6c
https://pubmed.ncbi.nlm.nih.gov/22521732
https://pubmed.ncbi.nlm.nih.gov/22521732
Background Phyllanthus amarus, a traditional herbal liver-protecting medicine, is known to contain an active ingredient phyllanthin. Many research studies and clinical trials performed in the past using this plant have given contentious results which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c72a625a0d8e129fcf18733fb2e1d5f
https://europepmc.org/articles/PMC3940533/
https://europepmc.org/articles/PMC3940533/
