Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rajesh K. Mistry"'
Expression of recombinant proteins in mammalian cell factories relies on synthetic assemblies of genetic parts to optimally control flux through the product biosynthetic pathway. In comparison to other genetic part-types, there is a relative paucity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e16ce1ab9332f7499b2aee00a954265
https://doi.org/10.1101/2023.03.14.532380
https://doi.org/10.1101/2023.03.14.532380
Autor:
Mike Jenns, Katie Willis, Fabio Zurlo, Rajesh K Mistry, Si Nga Sou, Diane Hatton, Emma J. Kelsall, Suzanne J. Gibson, Harriet Barker
Publikováno v:
Biotechnology and Bioengineering
The manufacture of bispecific antibodies by Chinese hamster ovary (CHO) cells is often hindered by lower product yields compared to monoclonal antibodies. Recently, reactive oxygen species have been shown to negatively impact antibody production. By
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca17e5608ddfa67f14ed69a9fe9d71d
https://doi.org/10.1002/bit.27744
https://doi.org/10.1002/bit.27744
Autor:
Anna Caldwell, Ralf P. Brandes, John M. Halket, Alison C. Brewer, Tracy Dew, Roy Sherwood, Katrin Schröder, Ajay M. Shah, Thomas V.A. Murray, Daniel Martin, Alberto Quaglia, Rajesh K. Mistry, Robin D. Hughes, Xuebin Dong, Greta J. Sawyer, Narayana Anilkumar, Simon Burr
Publikováno v:
Free Radical Biology & Medicine
Glutathione is the major intracellular redox buffer in the liver and is critical for hepatic detoxification of xenobiotics and other environmental toxins. Hepatic glutathione is also a major systemic store for other organs and thus impacts on patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520c717b1d4bf4b2c6a558abecebf0e4
https://doi.org/10.1016/j.freeradbiomed.2015.09.015
https://doi.org/10.1016/j.freeradbiomed.2015.09.015
Autor:
Shana M. de Silva, Thomas V.A. Murray, Matteo Beretta, Rajesh K. Mistry, Ioannis Smyrnias, Narayana Anilkumar, Ajay M. Shah, Daniel Martin, Moritz Schnelle, Alison C. Brewer, Min Zhang
Publikováno v:
Journal of Molecular and Cellular Cardiology
Adult mammalian cardiomyocytes have a very limited capacity to proliferate, and consequently the loss of cells after cardiac stress promotes heart failure. Recent evidence suggests that administration of hydrogen peroxide (H2O2), can regulate redox-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f79e94568758a813943a48138269cd
Autor:
Rajesh K, Mistry, Alison C, Brewer
Publikováno v:
Free Radical Biology & Medicine
Reactive oxygen species have emerged as key participants in a broad range of physiological and pathophysiological processes, not least within the vascular system. Diverse cellular functions which have been attributed to some of these pro-oxidants wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0cc10f01180ba96cf858ba877cbe8b7f
https://pubmed.ncbi.nlm.nih.gov/28433660
https://pubmed.ncbi.nlm.nih.gov/28433660