Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rajesh Jayachandran"'
Publikováno v:
Bio-Protocol, Vol 10, Iss 4 (2020)
Skin transplantation in mice is an important procedure to evaluate immune responses generated against heterologous grafts, especially given its highly immunogenic nature. In fact, skin is one of the most challenging organs in terms of allograft reten
Externí odkaz:
https://doaj.org/article/5f99b311b88048988837e1f531d04fdf
Autor:
Rajesh Jayachandran, Xiaolong Liu, Somdeb Bosedasgupta, Philipp Müller, Chun-Lei Zhang, Despina Moshous, Vera Studer, Jacques Schneider, Christel Genoud, Catherine Fossoud, Frédéric Gambino, Malik Khelfaoui, Christian Müller, Deborah Bartholdi, Helene Rossez, Michael Stiess, Xander Houbaert, Rolf Jaussi, Daniel Frey, Richard A Kammerer, Xavier Deupi, Jean-Pierre de Villartay, Andreas Lüthi, Yann Humeau, Jean Pieters
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001820 (2014)
Cognitive and behavioral disorders are thought to be a result of neuronal dysfunction, but the underlying molecular defects remain largely unknown. An important signaling pathway involved in the regulation of neuronal function is the cyclic AMP/Prote
Externí odkaz:
https://doaj.org/article/5f217f7498134941886d3e2799f2c271
Publikováno v:
FEBS lettersReferences. 596(20)
The origin of functional heterogeneity among macrophages, key innate immune system components, is still debated. While mouse strains differ in their immune responses, the range of gene expression variation among their pre-stimulation macrophages is u
Macrophages are cells of the innate immune system that provide the first line of defense against pathogens. Their functional and morphological heterogeneity is well known, though the origin of this heterogeneity is still debated. Furthermore, while m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf274ea69dd79b16aac24f2316c990e
https://doi.org/10.1101/2022.05.29.493868
https://doi.org/10.1101/2022.05.29.493868
Autor:
Tohnyui Ndinyanka Fabrice, Christelle Bianda, Haiyan Zhang, Rajesh Jayachandran, Julie Ruer-Laventie, Mayumi Mori, Despina Moshous, Geoffrey Fucile, Alexander Schmidt, Jean Pieters
Maintenance of cell population size is fundamental to the proper functioning of multicellular organisms. Here, we describe a cell-intrinsic cell density–sensing pathway that enabled T cells to reach and maintain an appropriate population size. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac5bf1910e40c412b050b83116416c3
https://edoc.unibas.ch/90570/
https://edoc.unibas.ch/90570/
Publikováno v:
Bio Protoc
Skin transplantation in mice is an important procedure to evaluate immune responses generated against heterologous grafts, especially given its highly immunogenic nature. In fact, skin is one of the most challenging organs in terms of allograft reten
Autor:
Kerstin Siegmund, George Holländer, Beatrice Claudi, Nina Khanna, Michael Stiess, Simone Dertschnig, Eva Medina, Mathias Jakob Lang, Aleksandra Gumienny, Simona W. Rossi, Gabriele Kunz, Saumyabrata Mazumder, Vincent S. Tchang, Urs Karrer, Geoffrey Fucile, Jianping Li, Rajesh Jayachandran, Dirk Bumann, Jean Pieters, Mathias Schmaler, Beatrice Bolinger, Sebastian Ruehl, Despina Moshous, Anne-Kathrin Woischnig
Publikováno v:
165.e8
Immunity
United States
Immunity
United States
The ability of the immune system to discriminate self from non-self is essential for eradicating microbial pathogens but is also responsible for allograft rejection. Whether it is possible to selectively suppress alloresponses while maintaining anti-
Autor:
Rajesh Jayachandran, Xiaolong Liu, Jean Pieters, Vera Studer, Sebastian Rühl, Somdeb BoseDasgupta, Michael Stiess
Publikováno v:
FEBS letters
Coronins constitute a family of conserved proteins expressed in all eukaryotes that have been implicated in the regulation of a wide variety of cellular activities. Recent work showed an essential role for coronin 1 in the modulation of the cAMP/PKA
Autor:
Rajesh Jayachandran, Jean Pieters
Publikováno v:
International immunopharmacology
Coronin 1 is the most recent candidate in the list of genes causing severe combined immunodeficiency (SCID) in humans. A distinctive feature of the SCID induced by coronin 1 deficiency is selective naive T cell lymphopenia in the presence of a normal
Publikováno v:
Nature Reviews Immunology
Nature reviews. Immunology
Nature reviews. Immunology
Recent work has implicated members of the evolutionarily conserved family of coronin proteins - in particular coronin 1 - in immune homeostasis. Coronins are involved in processes as diverse as pathogen survival in phagocytes and homeostatic T cell s