Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Rajesh C. Rao"'
Autor:
Le Tran Phuc Khoa, Wentao Yang, Mengrou Shan, Li Zhang, Fengbiao Mao, Bo Zhou, Qiang Li, Rebecca Malcore, Clair Harris, Lili Zhao, Rajesh C. Rao, Shigeki Iwase, Sundeep Kalantry, Stephanie L. Bielas, Costas A. Lyssiotis, Yali Dou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells (ESCs) can enter quiescence spontaneously or upon inhibition of MYC or fatty acid oxidation, mimi
Externí odkaz:
https://doaj.org/article/6b1a1bc377ca40f2bfe4471b19c2237e
Autor:
Rachana Haliyur, MD, PhD, David H. Parkinson, MS, Feiyang Ma, PhD, Jing Xu, PhD, Qiang Li, MD, PhD, Yuanhao Huang, Lam C. Tsoi, PhD, Rachael Bogle, MS, Jie Liu, PhD, Johann E. Gudjonsson, MD, Rajesh C. Rao, MD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 6, Pp 100539- (2024)
Purpose: Current therapies for proliferative diabetic retinopathy (PDR) do not specifically target VEGF-independent, cell-type–specific processes that lead to vision loss, such as inflammatory pathways. This study aimed to identify targetable cell
Externí odkaz:
https://doaj.org/article/f4ad998418104f48bf24a27ebc226ad3
Autor:
Le Tran Phuc Khoa, Wentao Yang, Mengrou Shan, Li Zhang, Fengbiao Mao, Bo Zhou, Qiang Li, Rebecca Malcore, Clair Harris, Lili Zhao, Rajesh C. Rao, Shigeki Iwase, Sundeep Kalantry, Stephanie L. Bielas, Costas A. Lyssiotis, Yali Dou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/99c1bf8c94c5449d90874ae8fbf5c9e4
Autor:
Nikhila S. Khandwala, Jason M.L. Miller, Robert A. Hyde, Christopher D. Conrady, Rajesh C. Rao, Cagri G. Besirli
Publikováno v:
Case Reports in Ophthalmology, Vol 12, Iss 1, Pp 164-168 (2021)
We report a finding of a pigmented chorioretinal scar with acute retinal necrosis (ARN) caused by herpes simplex virus 2 (HSV-2) infection rather than toxoplasma, creating an initial diagnostic dilemma. A 53-year-old functionally monocular male prese
Externí odkaz:
https://doaj.org/article/cb4dcbb900ae4a2c85913a459c54c9fc
Autor:
Qiang Li, Fengbiao Mao, Bo Zhou, Yuanhao Huang, Zhenhua Zou, Aaron D. denDekker, Jing Xu, Sean Hou, Jie Liu, Yali Dou, Rajesh C. Rao
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 465-480.e6 (2020)
Summary: How ubiquitous transcription factors (TFs) coordinate temporal inputs from broadly expressed epigenetic factors to control cell fate remains poorly understood. Here, we uncover a molecular relationship between p53, an abundant embryonic TF,
Externí odkaz:
https://doaj.org/article/1e32d07bf5fe4e77a971975d984c9031
Autor:
Daniel A. Balikov, Kevin Hu, Chia-Jen Liu, Bryan L. Betz, Arul M. Chinnaiyan, Laxmi V. Devisetty, Sriram Venneti, Scott A. Tomlins, Andi K. Cani, Rajesh C. Rao
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9992 (2021)
Primary Central Nervous System Lymphoma (PCNSL) is a lymphoid malignancy of the brain that occurs in ~1500 patients per year in the US. PCNSL can spread to the vitreous and retina, where it is known as vitreoretinal lymphoma (VRL). While confirmatory
Externí odkaz:
https://doaj.org/article/29dd01da13e849389ce55e06a4527957
Autor:
Andi K. Cani, Marcus A. Toral, Daniel A. Balikov, Bryan L. Betz, Kevin Hu, Chia-Jen Liu, Matthew V. Prifti, Arul M. Chinnaiyan, Scott A. Tomlins, Vinit B. Mahajan, Rajesh C. Rao
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6099 (2021)
Vitreoretinal lymphoma (VRL) is an uncommon eye malignancy, and VRLs of T cell origin are rare. They are difficult to treat, and their molecular underpinnings, including actionable genomic alterations, remain to be elucidated. At present, vitreous fl
Externí odkaz:
https://doaj.org/article/c64d1c95ad6b4baab1564d9aa9ccc88c
Autor:
Hakan Demirci, Rajesh C. Rao, Victor M. Elner, F. Yesim Demirci, Lev Axenov, Bryan Betz, Amir Behdad, Noah Brown
Publikováno v:
Ophthalmology Retina. 7:189-195
Autor:
Hana B. Ruran, Carter R. Petty, Dean Eliott, Rajesh C. Rao, Wanda Phipatanakul, Benjamin K. Young
Social media support groups can provide accessibility to advice and emotional regarding medical topics, such as retinal detachment repair, but this is almost universally provided by laypersons. We sought to determine how topics related to retinal det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2dbd2aa7088ea1e9324fdbea3f9d93
Autor:
Michael Aksu, Jie Liu, Rajesh C. Rao, Bo Zhou, Qiang Li, Yali Dou, Yuanhao Huang, Fengbiao Mao, Jing Xu, Lichao Sun, Brian W. Basinski
Publikováno v:
Stem Cell Reports
Summary p53 alterations occur during culture of pluripotent stem cells (PSCs), but the significance of these events on epigenetic control of PSC fate determination remains poorly understood. Wdr5 deletion in p53-null (DKO) mouse ESCs (mESCs) leads to