Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rajesh Basnet"'
Autor:
Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang, Rongqi Huang, Zhiyuan Li
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Esophageal cancer (EC) is a global canker notorious for causing high mortality due to its relentless incidence rate, convoluted with unyielding recurrence and metastasis. However, these intricacies of EC are associated with an imm
Externí odkaz:
https://doaj.org/article/18ff037bbc2044b898ab952d16040a0f
Autor:
Md Mahmudul Islam, Md Shah Alam, Zhiyong Liu, Mst Sumaia Khatun, Buhari Yusuf, H. M. Adnan Hameed, Xirong Tian, Chiranjibi Chhotaray, Rajesh Basnet, Haftay Abraha, Xiaofan Zhang, Shahzad Akbar Khan, Cuiting Fang, Chunyu Li, Sohel Hasan, Shouyong Tan, Nanshan Zhong, Jinxing Hu, Tianyu Zhang
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
Clofazimine (CFZ) and bedaquiline (BDQ) are currently used for the treatment of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains. In recent years, adding CFZ and BDQ to tuberculosis (TB) drug regimens against MDR Mtb strains has sig
Externí odkaz:
https://doaj.org/article/53aceef45fd5414d90a3e7b3c19004b3
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243063 (2020)
Dietary nutrients have significant effects on the risk of cardiovascular diseases. However, the results were not uniform across different countries. The study aims to determine the relative importance of dietary nutrients associated with coronary art
Externí odkaz:
https://doaj.org/article/cc605cc44ff84d8fb93bcef6f67a15a2
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 5, Pp 767-771 (2018)
The serum and glucocorticoid inducible protein kinase (SGK) family members share similar structure, substrate specificity and function with AKT and signal downstream of the phosphatidylinositol 3-kinase (PI3K) signalling pathway. They regulate a rang
Externí odkaz:
https://doaj.org/article/14e3d8be4e7c4fb0b87237ee11d8942b
Publikováno v:
Current Nanoscience. 18:717-725
Background: The spread of new coronavirus 2019, the causative agent of viral pneumonia documented in Wuhan, brought a recent public health crisis globally. The best solution to overcome this pandemic is developing suitable and effective vaccines and
Publikováno v:
Current Drug Therapy. 17:327-333
Abstract: The discovery and development of the drug/vaccine for Coronavirus Disease 2019 (COVID-19) is the process of developing a preventive vaccine or treatment drug to reduce the severity of COVID-19. Internationally, hundreds of pharmaceutical co
Autor:
Rajesh Basnet, Buddha Bahadur Basnet, Radheshyam Gupta, TilBahadur Basnet, Sandhya Khadka, Md Shan Alam
Publikováno v:
Current Molecular Pharmacology. 17
Background: The mammalian role of the rapamycin (mTOR) pathway is the practical nutrient-sensitive regulation of animal growth and plays a central role in physiology, metabolism, and common diseases. The mTOR is activated in response to nutrients, gr
Autor:
Buddha Bahadur Basnet, Rajesh Basnet
Publikováno v:
Current Signal Transduction Therapy. 16:122-128
The serum and glucocorticoid inducible protein kinase (SGK) family signals downstream of phosphoinositide-3-kinase (PI3K) and is made up of three isoforms: SGK1, 2, and 3. respectively, and their activity is dependent on growth factor activation. Amo
Autor:
Rajesh Basnet, Buddha Bahadur Basnet
Publikováno v:
Current Molecular Pharmacology. 14:527-536
Protein kinase B (AKT) PI3K / AKT / mTOR signaling pathways play a crucial role in modulating cell survival, proliferation, metastasis, metabolism, angiogenesis, and apoptosis. The AKT family consists of three isoforms: AKT1, AKT2, and AKT3. Moreover
Autor:
Radheshyam Gupta, Sandhya Khadka, Bidur Sharma, Buddhi Bal Chidi, Sanjeev Nirala, Rajesh Basnet, Buddha Bahadur Basnet, Til Bahadur Basnet
Publikováno v:
Current Rheumatology Reviews. 17:153-161
Background: Gout, inflammatory arthritis caused by the deposition of monosodium urate crystals into affected joints and other tissues, has become one of the major health problems of today's world. The main risk factor for gout is hyperuricemia, which